# Parahormonal Activity > Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Parahormonal_Activity > Markdown URL: https://mediated.wiki/source/Parahormonal_Activity.md > Source: https://en.wikipedia.org/wiki/Parahormonal_Activity > Source revision: 1357298443 > License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) Not to be confused with [Paranormal Activity](/source/Paranormal_Activity). 11th episode of the 37th season of The Simpsons "Parahormonal Activity" The Simpsons episode Episode no. Season 37 Episode 11 Directed by Chris Clements Written by Loni Steele Sosthand Production code 37ABF03 Original air date December 14, 2025 (2025-12-14) Guest appearances Lindsay Lohan as Maggie Simpson Jon Lovitz as Artie Ziff Megan Mullally as Sarah Wiggum Episode features Couch gag The Simpson family celebrates Marge's 39th birthday on the couch with flash forwards of subsequent birthdays until her 43rd birthday. She considers changing her hairstyle but declines because she is afraid. Episode chronology ← Previous "Guess Who's Coming to Skinner" Next → "¡The Fall Guy-Yi-Yi!" The Simpsons season 37 List of episodes "**Parahormonal Activity**" is the eleventh episode of the [thirty-seventh season](/source/The_Simpsons_season_37) of the American animated television series *[The Simpsons](/source/The_Simpsons)*, and the 801st episode overall. It aired in the United States on [Fox](/source/Fox_Broadcasting_Company) on December 14, 2025. The episode was written by Loni Steele Sosthand and directed by [Chris Clements](/source/Chris_Clements_(animation_director)). In this episode, the Simpson family experiences hormonal changes as they grow older. It features guest appearances by actor [Jon Lovitz](/source/Jon_Lovitz) as his recurring character [Artie Ziff](/source/Artie_Ziff), [Megan Mullally](/source/Megan_Mullally) as Sarah Wiggum, and [Lindsay Lohan](/source/Lindsay_Lohan) as the future version of [Maggie Simpson](/source/Maggie_Simpson). The episode received mixed reviews, with praise for Lohan's performance as Maggie. The episode was dedicated to the memory of [Frank Gehry](/source/Frank_Gehry) who guest starred as himself in "[The Seven-Beer Snitch](/source/The_Seven-Beer_Snitch)" and died nine days before the episode premiered. ## Plot Four years into the future, [Bart](/source/Bart_Simpson) and [Lisa](/source/Lisa_Simpson) are dealing with teenage hormones, with Lisa complaining about her acne, and they are always low on food because Bart eats it all. When Bart wants to drive the car, [Marge](/source/Marge_Simpson) forbids it after [Maggie](/source/Maggie_Simpson) mentions that Bart is an irresponsible driver. Driving Lisa to school, Marge tries to encourage Lisa, who has lost confidence in performing, to sing "[Escape (The Piña Colada Song)](/source/Escape_(The_Pi%C3%B1a_Colada_Song))" with her, and embarrasses Lisa by giving her a package in case she gets her first [period](/source/Menstruation). At [Luann](/source/Luann_Van_Houten)'s house, Marge's friends discuss experiencing [perimenopause](/source/Perimenopause). They describe their symptoms before they try [Botox](/source/Botox), but Marge declines. That night, Marge starts having symptoms. She notices Bart's [manga](/source/Manga) depicts a robot with large breasts which horrifies her, but [Homer](/source/Homer_Simpson) says it is better than adult films. When Marge realizes what is happening to her, she fears she is becoming old and becomes irritable hearing her children complain, so Homer takes charge to calm everyone down. After Marge encounters [Artie Ziff](/source/Artie_Ziff) who no longer finds her attractive, she desperately has Luann give her Botox, but Lisa catches her and angrily calls her a hypocrite. When Marge finds [adult films](/source/Pornographic_film) on Bart's tablet, she fears he will become someone who objectifies women. As a result, she bans electronic screens from the house. Marge gets [estrogen](/source/Estrogen) cream to handle her symptoms. Homer buys a smart refrigerator to quickly buy food when they run out. Impressed, Marge tries to have sex with Homer. When he is unable to perform, [Dr. Hibbert](/source/Dr._Hibbert) gives him [erectile dysfunction](/source/Erectile_dysfunction) medication which makes him aggressive. Later, the Simpsons prepare to attend [Ned Flanders](/source/Ned_Flanders)' wedding to a woman named Pam with Bart as the videographer and Lisa as the wedding singer. Marge and Lisa continue to argue and Marge says she is struggling with her changes. Lisa counters that she is handling her changes well because she dealt with her first period by herself. When Bart stops Homer from using the smart refrigerator's screen, Marge checks it to find that Bart used it to watch adult films, and destroys it. Due to Marge and Homer's irrational behavior, they have no choice but to let Bart drive. They forget the flowers that Maggie was going to throw as part of her flower girl job, so Marge has her improvise with potato chips at the wedding. At the wedding reception, an aggressive Homer takes Marge's estrogen to calm himself down, but becomes too emotional as a result and ends up giving a heartfelt toast to Ned, discarding the scathing roast he had planned earlier. Filming the reception, Bart sees a girl he likes and awkwardly talks to her, which relieves Marge's fears for him. She apologizes to Lisa and says she does not have to perform. However, when Marge experiences a [hot flash](/source/Hot_flash) because Homer used all the estrogen, Lisa sings and plays "Escape (The Piña Colada Song)" on a [Fender Esquire](/source/Fender_Esquire) on stage for her. ## Production [Jon Lovitz](/source/Jon_Lovitz) guest starred as Artie Ziff. This is the sixth future-themed *Simpsons* episode. [Lindsay Lohan](/source/Lindsay_Lohan) guest starred as the future [Maggie Simpson](/source/Maggie_Simpson).[1] [Jon Lovitz](/source/Jon_Lovitz) returned as a guest star to voice [Artie Ziff](/source/Artie_Ziff).[2] ## Release The episode aired simultaneously in the United States in all time zones at 8:31 PM ET/5:31 PM PT following a special episode of the television series *[Universal Basic Guys](/source/Universal_Basic_Guys)*.[2][3] ## Reception ### Critical response Marcus Gibson of *Bubbleblabber* gave the episode an 8.5 out of 10. He liked the episode's examination of common life problems through the lens of the show's characters. He also highlighted Lindsay Lohan's performance as Maggie.[4] Mike Celestino of *Laughing Place* wanted the episode to be funnier but liked the scene of Bart driving. He generally disliked flash-forward episodes because he did not like seeing the Simpson family at older ages.[5] Marisa Roffman of *Give Me My Remote* also highlighted Lohan's performance and the commentary about women's health research. She also liked that Flanders found love again.[6] Nick Valdez of *[Comicbook.com](/source/Comicbook.com)* ranked the episode number 8 on his list, "Every Episode of The Simpsons Season 37, Ranked Worst to Best." He said, "It's not exactly the best episode we've seen about the future, as it doesn't focus on Bart and Lisa's future, but it fits perfectly with the show's current identity. Each character feels like a natural extension of themselves, and there are plenty of funny sequences, like when Marge destroys her refrigerator. It's an entertaining episode that reveals a point in the timeline with a lot of potential for future storylines, so hopefully it's the first of many more."[7] ### Awards and nominations Writer Loni Steele Sosthand was nominated for the [Writers Guild of America Award for Television: Animation](/source/Writers_Guild_of_America_Award_for_Television%3A_Animation) at the [78th Writers Guild of America Awards](/source/78th_Writers_Guild_of_America_Awards) for her script for this episode.[8] ## References 1. **[^](#cite_ref-1)** Aslanian, Emily (December 12, 2025). ["Lindsay Lohan Guest Stars on 'The Simpsons' as Future Maggie (VIDEO)"](https://www.tvinsider.com/1233766/the-simpsons-exclusive-clip-maggie-lindsay-lohan/). *[TV Insider](/source/TV_Insider)*. Retrieved December 15, 2025. 1. ^ [***a***](#cite_ref-TFC_2-0) [***b***](#cite_ref-TFC_2-1) ["(SI-3703) "Parahormonal Activity""](http://www.thefutoncritic.com/listings/20251119fox14/). *[The Futon Critic](/source/The_Futon_Critic)*. Retrieved December 14, 2025. 1. **[^](#cite_ref-3)** ["(UBG-213) "Two Marks""](http://www.thefutoncritic.com/listings/20251119fox12/). *[The Futon Critic](/source/The_Futon_Critic)*. Retrieved December 14, 2025. 1. **[^](#cite_ref-4)** Gibson, Marcus (December 15, 2025). ["Review: The Simpsons "Parahormonal Activity""](https://www.bubbleblabber.com/2025/12/review-the-simpsons-parahormonal-activity/). *Bubbleblabber*. Retrieved December 15, 2025. 1. **[^](#cite_ref-5)** Celestino, Mike (December 14, 2025). ["TV Recap / Review: Marge Has a Middle-Age Meltdown in "The Simpsons" - "Parahormonal Activity""](https://www.laughingplace.com/entertainment/simpsons-s37e11-parahormonal-activity-recap-review/). *Laughing Place*. Retrieved December 14, 2025. 1. **[^](#cite_ref-6)** Roffman, Marisa (December 15, 2025). ["About Last Night…THE SIMPSONS and BOB'S BURGERS"](https://www.givememyremote.com/remote/2025/12/15/about-last-night-the-simpsons-and-bobs-burgers-7/). *Give Me My Remote*. Retrieved December 15, 2025. 1. **[^](#cite_ref-7)** Valdez, Nick (February 18, 2026). ["Every The Simpsons Season 37 Episode, Ranked Worst to Best"](https://comicbook.com/tv-shows/list/every-the-simpsons-season-37-episode-ranked-worst-to-best/). *[Comicbook.com](/source/Comicbook.com)*. Retrieved March 14, 2026. 1. **[^](#cite_ref-8)** Hipes, Patrick (January 27, 2026). ["'Sinners', 'One Battle After Another', 'Hamnet', 'Marty Supreme' Among WGA Awards Film Nominees; 'Pluribus' Tops TV"](https://deadline.com/2026/01/2026-wga-awards-nominations-list-1236697144/). *[Deadline Hollywood](/source/Deadline_Hollywood)*. Retrieved February 6, 2026. ## External links Wikiquote has quotations related to ***["Parahormonal Activity"](https://en.wikiquote.org/wiki/The_Simpsons/Season_37#Parahormonal_Activity)***. - [The Simpsons portal](https://en.wikipedia.org/wiki/Portal:The_Simpsons) - ["Parahormonal Activity"](https://www.imdb.com/title/tt36431493/) at [IMDb](/source/IMDb_(identifier)) v t e The Simpsons episodes Seasons 1–20 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Season 21–present 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 Season 37 "Thrifty Ways to Thieve Your Mother" "Keep Chalm and Gary On" "Treehouse of Horror XXXVI" "Men Behaving Manly" "Bad Boys... for Life?" "Bart 'N' Frink" "Sashes to Sashes" "The Day of the Jack-up" "Aunt Misbehavin'" "Guess Who's Coming to Skinner" "Parahormonal Activity" "¡The Fall Guy-Yi-Yi!" "Seperance" "Irrational Treasure" "Homer? A Cracker Bro?" "Extreme Makeover: Homer Edition" See also Treehouse of Horror list The Simpsons episode guides "The Simpsons Guy" Category --- Adapted from the Wikipedia article [Parahormonal Activity](https://en.wikipedia.org/wiki/Parahormonal_Activity) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Parahormonal_Activity?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.