# PART1

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/PART1
> Markdown URL: https://mediated.wiki/source/PART1.md
> Source: https://en.wikipedia.org/wiki/PART1
> Source revision: 1334075430
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

In molecular biology, **Prostate androgen-regulated transcript 1** (non-protein coding), also known as **PART1** is a [long non-coding RNA](/source/Long_non-coding_RNA). In humans, the PART-1 gene is located on [chromosome 5q](/source/Chromosome_5)12. It is highly expressed in the human [prostate gland](/source/Prostate_gland). Its expression in [prostate cancer](/source/Prostate_cancer) cells is increased in response to [androgens](/source/Androgens). It has been suggested that this gene may play a role in prostate [carcinogenesis](/source/Carcinogenesis).[1]

## See also

- [Long noncoding RNA](/source/Long_noncoding_RNA)

## References

1. Lin B, White JT, Ferguson C, Bumgarner R, Friedman C, Trask B, etal (2000). "PART-1: a novel human prostate-specific, androgen-regulated gene that maps to chromosome 5q12.". *Cancer Res*. **60** (4): 858–863. [PMID 10706094](https://pubmed.ncbi.nlm.nih.gov/10706094)

---
Adapted from the Wikipedia article [PART1](https://en.wikipedia.org/wiki/PART1) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/PART1?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.