# Oncocyte

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{{Short description|Epithelial cell with excess mitochondria}}
[[File:Cytopathology of Warthin's tumor.jpg|thumb|270px|[Cytopathology](/source/Cytopathology) of [Warthin's tumor](/source/Warthin's_tumor), with typical cellular features (and a relatively uncommon binucleated cell).<ref>Image by Mikael Häggström, MD. References for entries:<br>- {{cite journal| author=Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A| title=Cytomorphological findings in diagnosis of Warthin tumor | journal=Turk J Med Sci | year= 2020 | volume= 50 | issue= 1 | pages= 148–154 | pmid=31769640 | doi=10.3906/sag-1901-215  | doi-access=free| pmc=7080357 }}<br>Binucleation:<br>- {{cite web|url=http://repository-tnmgrmu.ac.in/464/1/200300307malliga.pdf|title=A correlative cytological and histopathological study on lesions of salivary gland|date=2006-10-18|author=Dr.S. Malliga}}<br>- Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b.</ref> [Pap stain](/source/Pap_stain). The relatively large size of the oncocytes is seen when comparing to the [lymphocyte](/source/lymphocyte).]]
[[File:Histopathology of apocrine metaplasia of breast, annotated.png|thumb|290px|[Micrograph](/source/Micrograph) showing [apocrine](/source/apocrine)-type [metaplasia](/source/metaplasia) of the breast with typical oncocytes.<ref>Image by Mikael Häggström, MD. Reference for findings: {{cite web|url=https://www.pathologyoutlines.com/topic/breastapocrinemetaplasia.html|title=Apocrine metaplasia|author=Carlos C. Diez Freire, M.D., Shahla Masood, M.D.|website=Pathology Outlines}} Last author update: 28 May 2020.</ref> [H&E stain](/source/H%26E_stain).]]
[[Image:Renal_oncocytoma2.jpg|right|thumb|'''Oncocytes''' (left of image), as seen in a [renal oncocytoma](/source/renal_oncocytoma). [H&E stain](/source/H%26E_stain).]]
An '''oncocyte''' is an [epithelial](/source/epithelial) [cell](/source/Cell_(biology)) characterized by an excessive number of [mitochondria](/source/mitochondria), resulting in an abundant [acidophil](/source/acidophil)ic, granular [cytoplasm](/source/cytoplasm). Oncocytes can be [benign](/source/benign) or [malignant](/source/malignant).

==Other names==
Also known as:
*''[Hürthle cell](/source/H%C3%BCrthle_cell)'' ([thyroid gland](/source/thyroid_gland) only)
*''[Oxyphilic cell](/source/Oxyphil_cell_(pathology))'' 
*''Askanazy cell''
*''[Apocrine](/source/Apocrine)-type [metaplasia](/source/metaplasia)'' (breast gland only).
*''Oncocytic cell''

==Etymology==
Derived from the Greek root '''onco-''', which means '''mass, bulk'''.

==See also==
*[Hurthle cell carcinoma](/source/Hurthle_cell_carcinoma), a variant of [follicular thyroid carcinoma](/source/follicular_thyroid_carcinoma).
*[Oncocytoma](/source/Oncocytoma), a tumour composed of oncocytes, may be found as a less common salivary gland neoplasm also known as oxyphilic adenoma.
*[Renal oncocytoma](/source/Renal_oncocytoma), a kidney tumour composed of oncocytes.

==References==
{{Reflist}}

==External links==
*[http://www.wordinfo.info/words/index/info/view_unit/1474 Wordinfo - words containing onco-, onocho-, -onchus]

Category:Epithelial cells
Category:Mitochondria
Category:Oncology

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