# Netrin G1

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{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Netrin-G1''' is a [protein](/source/protein) that in humans is encoded by the ''NTNG1'' [gene](/source/gene).<ref name="pmid10964959">{{cite journal | vauthors = Nakashiba T, Ikeda T, Nishimura S, Tashiro K, Honjo T, Culotti JG, Itohara S | title = Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins | journal = J Neurosci | volume = 20 | issue = 17 | pages = 6540–50 |date=Sep 2000 | pmid = 10964959 | doi =  10.1523/JNEUROSCI.20-17-06540.2000| pmc = 6772945 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NTNG1 netrin G1| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=22854}}</ref>

Netrin G1 (NTNG1) belongs to a conserved family of [proteins](/source/proteins) that act as [axon](/source/axon) guidance cues during [vertebrate](/source/vertebrate) nervous system development (Nakashiba et al., 2000).[supplied by OMIM]<ref name="entrez" />

==References==
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==Further reading==
{{refbegin | 2}}
*{{cite journal   |vauthors=Nagase T, Ishikawa K, Suyama M, etal |title=Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=6 |issue= 1 |pages= 63–70 |year= 1999 |pmid= 10231032 |doi=10.1093/dnares/6.1.63  |doi-access=free }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
*{{cite journal   |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003  | pmc=403697 }}
*{{cite journal  | vauthors=Lin JC, Ho WH, Gurney A, Rosenthal A |title=The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons |journal=Nat. Neurosci. |volume=6 |issue= 12 |pages= 1270–6 |year= 2004 |pmid= 14595443 |doi= 10.1038/nn1148 |s2cid=28353131 }}
*{{cite journal  | vauthors=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504  | pmc=2286551 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal   |vauthors=Fukasawa M, Aoki M, Yamada K, etal |title=Case-control association study of human netrin G1 gene in Japanese schizophrenia |journal=J. Med. Dent. Sci. |volume=51 |issue= 2 |pages= 121–8 |year= 2004 |pmid= 15508520 }}
*{{cite journal   |vauthors=Aoki-Suzuki M, Yamada K, Meerabux J, etal |title=A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia |journal=Biol. Psychiatry |volume=57 |issue= 4 |pages= 382–93 |year= 2005 |pmid= 15705354 |doi= 10.1016/j.biopsych.2004.11.022 |s2cid=19932857 }}
*{{cite journal   |vauthors=Borg I, Freude K, Kübart S, etal |title=Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome |journal=European Journal of Human Genetics |volume=13 |issue= 8 |pages= 921–7 |year= 2005 |pmid= 15870826 |doi= 10.1038/sj.ejhg.5201429 |doi-access= free }}
*{{cite journal   |vauthors=Meerabux JM, Ohba H, Fukasawa M, etal |title=Human netrin-G1 isoforms show evidence of differential expression |journal=Genomics |volume=86 |issue= 1 |pages= 112–6 |year= 2006 |pmid= 15901489 |doi= 10.1016/j.ygeno.2005.04.004 }}
*{{cite journal   |vauthors=Archer HL, Evans JC, Millar DS, etal |title=NTNG1 Mutations are a Rare Cause of Rett Syndrome |journal=American Journal of Medical Genetics |volume=140 |issue= 7 |pages= 691–4 |year= 2006 |pmid= 16502428 |doi= 10.1002/ajmg.a.31133  | pmc=2577736 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |bibcode=2006Natur.441..315G |doi-access= free }}
*{{cite journal   |vauthors=Nectoux J, Girard B, Bahi-Buisson N, etal |title=Netrin G1 mutations are an uncommon cause of atypical Rett syndrome with or without epilepsy |journal=Pediatr. Neurol. |volume=37 |issue= 4 |pages= 270–4 |year= 2007 |pmid= 17903671 |doi= 10.1016/j.pediatrneurol.2007.06.002 }}
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Category:Netrins

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Adapted from the Wikipedia article [Netrin G1](https://en.wikipedia.org/wiki/Netrin_G1) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Netrin_G1?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.