# NeXtProt

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/NeXtProt
> Markdown URL: https://mediated.wiki/source/NeXtProt.md
> Source: https://en.wikipedia.org/wiki/NeXtProt
> Source revision: 1240686542
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Multiple issues|
{{coi|date=July 2018}}
{{primary|date=July 2018}}
{{notability|date=July 2018}}
}}
{{infobox biodatabase
|title = neXtProt
|logo = right
|description = '''neXtProt''': exploring the universe of human proteins
|scope = Protein annotation
|organism = [Human](/source/Human)
|center = [Swiss Institute of Bioinformatics](/source/Swiss_Institute_of_Bioinformatics)
|laboratory = CALIPHO 
|author =
|citation = Gaudet, ''et al.'' (2016)<ref>{{cite journal|last1=Gaudet|first1=P|last2=Michel|first2=PA|last3=Zahn-Zabal|first3=M|last4=Britan|first4=A|last5=Cusin|first5=I|last6=Domagalski|first6=M|last7=Duek|first7=PD|last8=Gateau|first8=A|last9=Gleizes|first9=A|last10=Hinard|first10=V|last11=de Laval|first11=VR|last12=Lin|first12=J|last13=Nikitin|first13=F|last14=Schaeffer|first14=M|last15=Teixeira|first15=D|last16=Lane|first16=L|last17=Bairoch|first17=A|title=The neXtProt knowledgebase on human proteins: 2017 update.|journal=Nucleic Acids Research|date=29 November 2016|pmid=27899619|doi=10.1093/nar/gkw1062|volume=45|issue=D1|pmc=5210547|pages=D177–D182}}</ref> 
|pmid = 
|released = 
|standard = 
|format = 
|url = {{URL|www.nextprot.org}}
|download = 
|webservice =
|sql =
|sparql = 
|webapp = Search, [BLAST](/source/BLAST_(biotechnology)), SNORQL
|standalone = 
|news = 
|license = [Creative Commons](/source/Creative_Commons) Attribution 4.0
|versioning = Yes
|frequency = Data: 3 times per year
|curation = Yes - manual and automatic
|bookmark = Yes - individual protein entries views and searches
|version =
}}

'''neXtProt''' is an on-line knowledge platform on human [proteins](/source/proteins).
It strives to be a comprehensive resource that provides a variety of
types of information on human proteins, such as their function, 
subcellular location, expression, interactions and role in diseases.
The major part of the information in neXtProt
<ref name=Lane2002>{{cite journal |author=Lane Lydie|title=neXtProt: a knowledge platform for human proteins |journal=Nucleic Acids Research |volume=40 |pages=D76–D83 |year=2012 |pmid=22139911  |doi=10.1093/nar/gkr1179 |issue=Database issue |pmc=3245017}}</ref>
is obtained from the [UniProt](/source/UniProt) Swiss-Prot [database](/source/database) but it is complemented by data originating from high-throughput studies with an emphasis on [proteomics](/source/proteomics). neXtProt offers also an advanced search capacity based on the [SPARQL](/source/SPARQL) technology as well as an API that allows to programmatically extract the data stored in the resource. It is developed by the CALIPHO group<ref>[http://www.isb-sib.ch/bairoch-amos-lane-lydie/bairoch-amos-lane-lydie-sub CALIPHO group], on the web site of the SIB</ref> directed by [Amos Bairoch](/source/Amos_Bairoch) and Lydie Lane of the [Swiss Institute of Bioinformatics](/source/Swiss_Institute_of_Bioinformatics) (SIB).

==References==
{{reflist}}

==External links==
*[https://www.nextprot.org/ neXtProt] - Exploring the universe of human proteins
*[https://www.uniprot.org/ UniProt] - The Universal protein resource
*[https://www.sib.swiss/ SIB] - The Swiss Institute of Bioinformatics
*[https://github.com/calipho-sib GitHub directory for neXtProt code]

{{Biology-footer}}

<!-- Categories -->
Category:Protein databases
Category:Human biology

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Adapted from the Wikipedia article [NeXtProt](https://en.wikipedia.org/wiki/NeXtProt) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/NeXtProt?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.
