# Nature Protocols

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***Nature Protocols***, published by the [Nature Publishing Group](/source/Nature_Publishing_Group), is an on-line [scientific journal](/source/Scientific_journal) publishing methods in a recipe-style format. The journal was launched in June 2006 and the content includes both classical methods and cutting-edge techniques relevant to the study of biological problems. The content on this site is divided into "Nature Protocols" and the "Protocol Exchange".

Initially, all "Nature Protocols" were commissioned by editors, but it is now possible for authors to upload pre-submission enquiries. All Nature Protocols are [peer-reviewed](/source/Peer-review), fully edited and styled prior to publication. New protocols are added to the site on a weekly basis.

## Published protocols

Published protocols are sorted into the following categories:

- [Biochemistry](/source/Biochemistry)
- Cell and tissue culture
- [Cell biology](/source/Cell_biology) and [developmental biology](/source/Developmental_biology) (includes detection of [apoptosis](/source/Apoptosis) and others)
- [Computational biology](/source/Computational_biology) and theoretical biology (includes [bioinformatics](/source/Bioinformatics))
- [Genetic analysis](/source/Genetic_analysis) (includes [classical genetics](/source/Classical_genetics), [reverse genetics](/source/Reverse_genetics), mutation detection and others)
- Genetic modification (includes [transgenes](/source/Transgene), [transfection](/source/Transfection), [transformation (genetics)](/source/Transformation_(genetics)) and other [gene delivery](/source/Gene_delivery) techniques)
- [Genomics](/source/Genomics) and [proteomics](/source/Proteomics) (includes [microarrays](/source/Microarray) and others)
- [Imaging](/source/Medical_imaging) (includes [microscopy](/source/Microscopy), [MRI](/source/Magnetic_resonance_imaging), [SPECT](/source/Single_photon_emission_computed_tomography) and [PET](/source/Positron_emission_tomography))
- Immunological techniques
- Isolation and Purification (includes [cell fractionation](/source/Cell_fractionation) and others)
- [Microbiology](/source/Microbiology) and [virology](/source/Virology)
- [Molecular biology](/source/Molecular_biology) (includes [PCR](/source/Polymerase_chain_reaction), [cloning](/source/Cloning), [Southern blot](/source/Southern_blot) and other DNA and RNA based techniques)
- [Model organisms](/source/Model_organism) (includes [*Drosophila*](/source/Drosophila_melanogaster), [*C. elegans*](/source/Caenorhabditis_elegans), [*Xenopus*](/source/Xenopus_laevis), [zebrafish](/source/Zebrafish), [mouse](/source/Laboratory_mice), [*Arabidopsis*](/source/Arabidopsis_thaliana), [*Aspergillus*](/source/Aspergillus_nidulans), [*Dictyostelium*](/source/Dictyostelium_discoideum) and others )
- [Neuroscience](/source/Neuroscience)
- [Pharmacology](/source/Pharmacology) and [toxicology](/source/Toxicology)
- Plant biology
- [Spectroscopy](/source/Spectroscopy) and structural analysis (includes protein [mass spectrometry](/source/Mass_spectrometry) and [nuclear magnetic resonance](/source/Nuclear_magnetic_resonance))
- Synthetic [chemistry](/source/Chemistry), chemical modifications, [nanotechnology](/source/Nanotechnology)

## Participation

Scientists can participate directly in the Protocol Exchange section of this site. The Protocol Exchange replaced the Protocols Network in December 2010;[1] all content from the Protocols Network was transferred to the Exchange. It is an open-access, online resource that allows researchers to share their detailed experimental know-how. All uploaded protocols are made freely available, assigned DOIs for ease of citation and fully searchable through nature.com. These protocols are not further styled, peer-reviewed or copy edited, but posted live soon after submission. Protocols can be linked to any publications in which they are used. Each Lab Group can establish a dedicated page to collect their lab Protocols. By uploading Protocols to Protocol Exchange, scientists can enable other researchers to more readily reproduce or adapt the methodology they use, as well as increasing the visibility of their protocols and papers.[2][3]

## See also

- [Nature](/source/Nature_(journal))
- [Protocol (natural sciences)](/source/Protocol_(natural_sciences))

## Reference list

1. [An Exchange of Views](http://blogs.nature.com/natprot/2010/12/01/exchange-protocols). Nature Protocols Blog. Dec 1, 2010

1. [Welcome to the Protocol Exchange](http://www.nature.com/protocolexchange/). nature.com

1. [About Protocol Exchange](http://www.nature.com/protocolexchange/about). nature.com

## External links

- [The Nature Protocols website](http://www.nature.com/nprot/index.html)

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Adapted from the Wikipedia article [Nature Protocols](https://en.wikipedia.org/wiki/Nature_Protocols) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Nature_Protocols?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.