# MvirDB

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{{Short description|Biological database}}
{{Infobox biodatabase
|title=MvirDB|logo=
|description=A database of toxins, virulence factors and antibiotic resistance genes|scope=Toxins, Virulence Factors and Antibiotic resistance genes|organism=[Bacteria](/source/Bacteria)|center=|laboratory=|author=|pmid=17090593|released=|standard=|format=|url={{URL|http://mvirdb.llnl.gov/}}|download=|webservice=|sql=|sparql=|webapp=|standalone=|license=|versioning=|frequency=|curation=|bookmark=yes|version=
}}
In [molecular biology](/source/molecular_biology), '''MvirDB''' was a publicly available [database](/source/Biological_database) that stored information on [toxin](/source/toxin)s, [virulence factor](/source/virulence_factor)s and [antibiotic resistance](/source/Antimicrobial_resistance) genes.<ref name=":0">{{Cite journal|last1=Zhou|first1=C. E.|last2=Smith|first2=J.|last3=Lam|first3=M.|last4=Zemla|first4=A.|last5=Dyer|first5=M. D.|last6=Slezak|first6=T.|date=2007-01-03|title=MvirDB--a microbial database of protein toxins, virulence factors and antibiotic resistance genes for bio-defence applications |journal=Nucleic Acids Research|volume=35|issue=Database|pages=D391–D394|doi=10.1093/nar/gkl791|pmid=17090593|issn=0305-1048|pmc=1669772}}</ref> Sources that this database used for [DNA](/source/DNA) and [protein](/source/protein) information included: Tox-Prot,<ref>{{Cite journal|last1=Jungo|first1=Florence|last2=Bairoch|first2=Amos|date=March 2005|title=Tox-Prot, the toxin protein annotation program of the Swiss-Prot protein knowledgebase |journal=Toxicon|volume=45|issue=3|pages=293–301|doi=10.1016/j.toxicon.2004.10.018|pmid=15683867|bibcode=2005Txcn...45..293J |issn=0041-0101}}</ref> SCORPION,<ref>{{Cite journal|last1=Srinivasan|first1=K.N.|last2=Gopalakrishnakone|first2=P.|last3=Tan|first3=P.T.|last4=Chew|first4=K.C.|last5=Cheng|first5=B.|last6=Kini|first6=R.M.|last7=Koh|first7=J.L.Y.|last8=Seah|first8=S.H.|last9=Brusic|first9=V.|date=January 2002|title=SCORPION, a molecular database of scorpion toxins |journal=Toxicon|volume=40|issue=1|pages=23–31|doi=10.1016/s0041-0101(01)00182-9|pmid=11602275|bibcode=2002Txcn...40...23S |issn=0041-0101 |url=http://scholarbank.nus.edu.sg/handle/10635/33891 }}</ref> the PRINTS Virulence Factors,<ref>{{Cite journal|date=2008|title=Author Index Vol. 15, No. 1, 2008 |journal=Journal of Molecular Microbiology and Biotechnology|volume=15|issue=1|pages=65|doi=10.1159/000121450|issn=1464-1801|doi-access=free}}</ref><ref>{{Citation|last1=Attwood|first1=Teresa K.|title=The PRINTS protein fingerprint database: functional and evolutionary applications|date=2005-04-15|doi=10.1002/047001153x.g306301|encyclopedia=Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics|publisher=John Wiley & Sons, Ltd|isbn=047001153X|last2=Bradley|first2=Paul M.|last3=Gaulton|first3=Anna|last4=Maudling|first4=Neil|last5=Mitchell|first5=Alexander L.|last6=Moulton|first6=Georgina}}</ref> [VFDB](/source/VFDB),<ref>{{Cite journal|last=Chen|first=L.|date=2004-12-17|title=VFDB: a reference database for bacterial virulence factors |journal=Nucleic Acids Research|volume=33|issue=Database issue|pages=D325–D328|doi=10.1093/nar/gki008|pmid=15608208|issn=1362-4962|pmc=539962}}</ref> TVFac, Islander,<ref>{{Cite journal|last=Mantri|first=Y.|date=2004-01-01|title=Islander: a database of integrative islands in prokaryotic genomes, the associated integrases and their DNA site specificities |journal=Nucleic Acids Research|volume=32|issue=90001|pages=55D–58|doi=10.1093/nar/gkh059|pmid=14681358|pmc=308793|issn=1362-4962}}</ref> ARGO<ref>{{Cite journal|last1=Scaria|first1=Joy|last2=Chandramouli|first2=Umamaheswaran|last3=Verma|first3=Sanjay Kumar|date=2005-02-01|title=Antibiotic Resistance Genes Online (ARGO): A Database on vancomycin and b-lactam resistance genes |journal=Bioinformation|volume=1|issue=1|pages=5–7|doi=10.6026/97320630001005|pmid=17597841|pmc=1891619|issn=0973-8894|doi-access=free}}</ref> and VIDA.<ref>{{Cite journal|last1=Yeats|first1=C.|last2=Lees|first2=J.|last3=Reid|first3=A.|last4=Kellam|first4=P.|last5=Martin|first5=N.|last6=Liu|first6=X.|last7=Orengo|first7=C.|date=2007-12-23|title=Gene3D: comprehensive structural and functional annotation of genomes |journal=Nucleic Acids Research|volume=36|issue=Database|pages=D414–D418|pmc=2238970| doi=10.1093/nar/gkm1019|pmid=18032434|issn=0305-1048|doi-access=free}}</ref> The database provided a [BLAST](/source/BLAST_(biotechnology)) tool that allowed the user to query their sequence against all [DNA](/source/DNA) and [protein](/source/protein) sequences in MvirDB. Information on [virulence factor](/source/virulence_factor)s could be obtained from the usage of the provided browser tool. Once the browser tool was used, the results were returned as a readable table that was organized by ascending E-Values, each of which were hyperlinked to their related page. MvirDB was implemented in an [Oracle 10g](/source/Oracle_Database) relational database.<ref name=":0" /> MvirDB appears to have been inactive for some time, and is therefore not current. The last available [https://Web.archive.org/web/20170802134700/http://mvirdb.llnl.gov snapshot] was made on August 2, 2017.

== See also ==

* [Antimicrobial Resistance databases](/source/List_of_biological_databases)

== References ==
{{Reflist}}

Category:Antimicrobial resistance organizations
Category:Biological databases

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Adapted from the Wikipedia article [MvirDB](https://en.wikipedia.org/wiki/MvirDB) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/MvirDB?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.
