# Methanol toxicity

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Medical condition (poisoning)

Medical condition

Methanol toxicity Other names Methanol poisoning, methanol overdose Molecular structure of methanol Specialty Emergency medicine, toxicology Symptoms Decreased level of consciousness, ataxia, vomiting, abdominal pain, specific smell on the breath[1][2] Complications Blindness, kidney failure, death[1] Causes Methanol (such as found in windshield washer fluid)[1][2] Diagnostic method Blood acidosis, increased osmol gap, methanol blood level[1][2] Differential diagnosis Infections, exposure to other toxic alcohols, serotonin syndrome, diabetic ketoacidosis[2] Prevention Consuming safe alcoholic beverages Treatment Antidote, hemodialysis[2] Medication Fomepizole, ethanol[2] Prognosis Good with early treatment[1] Frequency 1,700 cases per year (US)[3]

**Methanol toxicity** (also **methanol poisoning**) is [poisoning](/source/Poisoning) from [methanol](/source/Methanol), characteristically via ingestion.[1] Symptoms may include an [altered/decreased level of consciousness](/source/Altered_level_of_consciousness), poor or no coordination, [vomiting](/source/Vomiting), [abdominal pain](/source/Abdominal_pain), and a specific smell on the breath.[1][2] [Decreased vision](/source/Decreased_vision) may start as early as twelve hours after exposure.[2] Long-term outcomes may include blindness and [kidney failure](/source/Kidney_failure).[1] Ingestion of as little as 3.16 grams of methanol can cause irreversible [optic nerve damage](/source/Toxic_and_nutritional_optic_neuropathy), and the oral [LD50](/source/LD50) for humans is estimated to be 56.2 grams of pure methanol.[4]

Methanol poisoning most commonly occurs following the drinking of tainted [alcoholic beverages](/source/Alcoholic_beverage) made with [windshield washer fluid](/source/Windshield_washer_fluid).[2] This may be accidental or as part of an [attempted suicide](/source/Suicide). [Toxicity](/source/Toxicity) may also rarely occur through extensive skin exposure or breathing in fumes.[1] When the body breaks down methanol it results in the creation of metabolite byproducts such as [formaldehyde](/source/Formaldehyde), [formic acid](/source/Formic_acid), and [formate](/source/Formate) which cause much of the toxicity.[2] The diagnosis may be suspected when there is [acidosis](/source/Acidosis) or an increased [osmol gap](/source/Osmol_gap) and confirmed by directly measuring blood levels.[1][2] Other conditions that can produce similar symptoms include [infections](/source/Infections), exposure to other [toxic alcohols](/source/Toxic_alcohol), [serotonin syndrome](/source/Serotonin_syndrome), and [diabetic ketoacidosis](/source/Diabetic_ketoacidosis).[2]

Early treatment increases the chance of a good outcome. Treatment consists of stabilizing the person and using an [antidote](/source/Antidote). The preferred antidote is [fomepizole](/source/Fomepizole), with [ethanol](/source/Ethanol) used if this is not available. [Hemodialysis](/source/Hemodialysis) may also be used in those where there is [organ](/source/Organ_(anatomy)) damage or a high degree of [acidosis](/source/Acidosis). Other treatments may include [sodium bicarbonate](/source/Sodium_bicarbonate), [folate](/source/Folate), and [thiamine](/source/Thiamine).[2]

Oral methanol toxicity is more common in the [developing world](/source/Developing_world).[2] In 2013 more than 1700 cases occurred in the United States. Those affected are usually adults and males.[3] Toxicity to methanol has been described as early as 1856.[5]

## Signs and symptoms

The initial symptoms of methanol intoxication include [central nervous system depression](/source/Central_nervous_system_depression), headache, dizziness, nausea, lack of coordination, and confusion. Sufficiently large doses cause unconsciousness and death. The initial symptoms of methanol exposure are usually less severe than the symptoms from the ingestion of a similar quantity of ethanol.[6] Once the initial symptoms have passed, a second set of symptoms arises, from 10 to as many as 30 hours after the initial exposure, that may include blurring, [photophobia](/source/Photophobia), snowstorm vision or complete loss of vision, [acidosis](/source/Acidosis), and [putaminal](/source/Putamen) hemorrhages, an uncommon but serious complication.[7][8] These symptoms result from the accumulation of toxic levels of [formate](/source/Formate) in the blood, and may progress to death by [respiratory failure](/source/Respiratory_failure). Physical examination may show [tachypnea](/source/Tachypnea), and eye examination may show dilated [pupils](/source/Pupil) with [hyperemia](/source/Hyperemia) of the optic disc and [retinal](/source/Retina) [edema](/source/Edema).

## Cause

Ingestion of as little as 4–15 mL of methanol has reportedly caused irreversible [optic nerve damage](/source/Toxic_and_nutritional_optic_neuropathy), and the oral [LD50](/source/LD50) for humans is estimated to be 56.2 grams of pure methanol.[4] The toxicity is attenuated (not removed) when methanol is ingested with ethanol (such as in the case of tainted drinks), increasing the doses required for symptoms and death.[4][9] The [reference dose](/source/Reference_dose) for methanol is 0.5 mg/kg/day.[10]

[Methanol](/source/Methanol) is not produced in toxic amounts by fermentation of agricultural products or by subsequent distillation.[11] However, in modern times, in order to comply with regulations reducing the methanol amount is sometimes desired.[12] This can be achieved with the use of a [molecular sieve](/source/Molecular_sieve).[13]

### Surrogate alcohol

See also: [Surrogate alcohol](/source/Surrogate_alcohol)

Because of its similarities in both appearance and odor to [ethanol](/source/Ethanol) (the alcohol in beverages) or [isopropyl alcohol](/source/Isopropyl_alcohol), it is difficult to differentiate between the three.[14] As a result, ethanol is sometimes [denatured](/source/Denatured_alcohol) (adulterated), and made poisonous, by the addition of methanol. The result is known as methylated spirit, "meths" ([British](/source/British_English) use) or "metho" ([Australian](/source/Australian_English) slang).[15]

Despite its poisonous content, denatured alcohol is sometimes consumed as a [surrogate alcohol](/source/Surrogate_alcohol).[16][17][18]

## Mechanism

Methanol is [toxic](/source/Toxic) by two mechanisms. First, methanol (whether it enters the body by [ingestion](/source/Ingestion), [inhalation](/source/Inhalation), or [absorption](/source/Absorption_(chemistry)) through the skin) can be fatal due to its [CNS depressant](/source/CNS_depressant) properties in the same manner as [ethanol poisoning](/source/Alcohol_intoxication#Acute_alcohol_poisoning). Second, in a process of [toxication](/source/Toxication), it is [metabolized](/source/Metabolism) to [formic acid](/source/Formic_acid) (which is present as the formate ion) via [formaldehyde](/source/Formaldehyde) in a process initiated by the [enzyme](/source/Enzyme) [alcohol dehydrogenase](/source/Alcohol_dehydrogenase) in the [liver](/source/Liver).[19] Methanol is converted to formaldehyde via alcohol dehydrogenase and formaldehyde is converted to formic acid (formate) via [aldehyde dehydrogenase](/source/Aldehyde_dehydrogenase). The conversion to formate via ALDH proceeds completely, with no detectable formaldehyde remaining.[20] Formate is toxic because it inhibits mitochondrial [cytochrome c oxidase](/source/Cytochrome_c_oxidase), causing [hypoxia](/source/Hypoxia_(medical)) at the cellular level, and [metabolic acidosis](/source/Metabolic_acidosis), among a variety of other metabolic disturbances.[21]

## Treatment

Methanol poisoning can be treated with [fomepizole](/source/Fomepizole) or ethanol.[19][22][23] Both drugs act to reduce the action of [alcohol dehydrogenase](/source/Alcohol_dehydrogenase) on methanol by means of [competitive inhibition](/source/Competitive_inhibition). [Ethanol](/source/Ethanol), the active ingredient in alcoholic beverages, acts as a competitive inhibitor by more effectively binding and saturating the alcohol dehydrogenase enzyme in the liver, thus blocking the binding of methanol. Methanol is excreted by the [kidneys](/source/Kidney) without being converted into the toxic metabolites formaldehyde and formic acid. Alcohol dehydrogenase instead enzymatically converts ethanol to [acetaldehyde](/source/Acetaldehyde).[19][24] Additional treatment may include [sodium bicarbonate](/source/Sodium_bicarbonate) for metabolic acidosis, and [hemodialysis](/source/Hemodialysis) or [hemodiafiltration](/source/Hemodiafiltration) to remove methanol and formate from the blood.[19] [Folinic acid](/source/Folinic_acid) or [folic acid](/source/Folic_acid) is also administered to enhance the metabolism of formate.[19]

## History

See also: [List of methanol poisoning incidents](/source/List_of_methanol_poisoning_incidents)

There are cases of methanol resistance, such as that of [Michael Malloy](/source/Michael_Malloy), whom a group of acquaintances tried and failed to poison with methanol in the early 1930s.[25]

In December 2016, [78 people died in Irkutsk, Russia](/source/2016_Irkutsk_mass_methanol_poisoning), from methanol poisoning after ingesting a [counterfeit](/source/Counterfeit) body [lotion](/source/Lotion) that was primarily methanol rather than ethanol as labeled. The body lotion, before the event, had been used as a cheap substitute for [vodka](/source/Vodka) by the impoverished people in the region despite warnings on the lotion's bottles that it was not safe for drinking and long-standing problems with alcohol poisoning across the country.[26]

During the [COVID-19 pandemic](/source/COVID-19_pandemic), Iranian media reported that nearly 300 people had died and over a thousand became ill due to methanol poisoning in the belief that drinking methanol could help with the disease.[27] In the United States, the [Food and Drug Administration](/source/Food_and_Drug_Administration) discovered that several brands of [hand sanitizer](/source/Hand_sanitizer) manufactured in Mexico during the pandemic contained methanol, and urged the public to avoid using the affected products.[28]

In June 2025, 57 people were poisoned by tainted alcoholic beverages in [Jordan](/source/Jordan). Nine people died from the incident. Jordanian Authorities arrested 12 individuals that are linked to the factory which manufactured the contaminated alcoholic beverages. All 12 were charged with murder and attempted murder.[29][30]

## See also

- [Ethylene glycol poisoning](/source/Ethylene_glycol_poisoning)

## References

1. ^ [***a***](#cite_ref-Kr2012_1-0) [***b***](#cite_ref-Kr2012_1-1) [***c***](#cite_ref-Kr2012_1-2) [***d***](#cite_ref-Kr2012_1-3) [***e***](#cite_ref-Kr2012_1-4) [***f***](#cite_ref-Kr2012_1-5) [***g***](#cite_ref-Kr2012_1-6) [***h***](#cite_ref-Kr2012_1-7) [***i***](#cite_ref-Kr2012_1-8) [***j***](#cite_ref-Kr2012_1-9) Kruse JA (October 2012). "Methanol and ethylene glycol intoxication". *Critical Care Clinics*. **28** (4): 661–711. [doi](/source/Doi_(identifier)):[10.1016/j.ccc.2012.07.002](https://doi.org/10.1016%2Fj.ccc.2012.07.002). [PMID](/source/PMID_(identifier)) [22998995](https://pubmed.ncbi.nlm.nih.gov/22998995).

1. ^ [***a***](#cite_ref-EM2016_2-0) [***b***](#cite_ref-EM2016_2-1) [***c***](#cite_ref-EM2016_2-2) [***d***](#cite_ref-EM2016_2-3) [***e***](#cite_ref-EM2016_2-4) [***f***](#cite_ref-EM2016_2-5) [***g***](#cite_ref-EM2016_2-6) [***h***](#cite_ref-EM2016_2-7) [***i***](#cite_ref-EM2016_2-8) [***j***](#cite_ref-EM2016_2-9) [***k***](#cite_ref-EM2016_2-10) [***l***](#cite_ref-EM2016_2-11) [***m***](#cite_ref-EM2016_2-12) [***n***](#cite_ref-EM2016_2-13) Beauchamp GA, Valento M (September 2016). "Toxic Alcohol Ingestion: Prompt Recognition And Management In The Emergency Department". *Emergency Medicine Practice*. **18** (9): 1–20. [PMID](/source/PMID_(identifier)) [27538060](https://pubmed.ncbi.nlm.nih.gov/27538060).

1. ^ [***a***](#cite_ref-Fer2016_3-0) [***b***](#cite_ref-Fer2016_3-1) Ferri FF (2016). [*Ferri's Clinical Advisor 2017: 5 Books in 1*](https://books.google.com/books?id=rRhCDAAAQBAJ&pg=PA794). Elsevier Health Sciences. p. 794. [ISBN](/source/ISBN_(identifier)) [978-0-323-44838-3](https://en.wikipedia.org/wiki/Special:BookSources/978-0-323-44838-3). [Archived](https://web.archive.org/web/20170908221935/https://books.google.com/books?id=rRhCDAAAQBAJ&pg=PA794) from the original on 2017-09-08.

1. ^ [***a***](#cite_ref-Moon_4-0) [***b***](#cite_ref-Moon_4-1) [***c***](#cite_ref-Moon_4-2) Moon, C. S. (2017). ["Estimations of the lethal and exposure doses for representative methanol symptoms in humans"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625597). *Annals of Occupational and Environmental Medicine*. **29** 44. [doi](/source/Doi_(identifier)):[10.1186/s40557-017-0197-5](https://doi.org/10.1186%2Fs40557-017-0197-5). [PMC](/source/PMC_(identifier)) [5625597](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625597). [PMID](/source/PMID_(identifier)) [29026612](https://pubmed.ncbi.nlm.nih.gov/29026612).

1. **[^](#cite_ref-5)** Clary JJ (2013). [*The Toxicology of Methanol*](https://books.google.com/books?id=xSs8oDQV4uYC&pg=PT44). John Wiley & Sons. p. 3.4.1. [ISBN](/source/ISBN_(identifier)) [978-1-118-35310-3](https://en.wikipedia.org/wiki/Special:BookSources/978-1-118-35310-3). [Archived](https://web.archive.org/web/20170908221935/https://books.google.com/books?id=xSs8oDQV4uYC&pg=PT44) from the original on 2017-09-08.

1. **[^](#cite_ref-ershdb_6-0)** National Institute for Occupational Safety and Health (22 August 2008). ["The Emergency Response Safety and Health Database: Methanol"](https://www.cdc.gov/niosh/ershdb/EmergencyResponseCard_29750029.html). [Archived](https://web.archive.org/web/20090423005724/http://www.cdc.gov/niosh/ershdb/EmergencyResponseCard_29750029.html) from the original on 23 April 2009. Retrieved 17 March 2009.

1. **[^](#cite_ref-7)** Jafarizadeh, A., Homaie, M., Abdollahi, M., & Niyousha, M. (2023). Time course study of optical coherence tomography angiography in patients with methanol-induced optic neuropathy. BMC ophthalmology, 23(1), 178. [https://doi.org/10.1186/s12886-023-02937-x](https://doi.org/10.1186/s12886-023-02937-x)

1. **[^](#cite_ref-8)** Permpalung N, Cheungpasitporn W, Chongnarungsin D, Hodgdon TM (Oct 2013). ["Bilateral putaminal hemorrhages: serious complication of methanol intoxication"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842708). *N Am J Med Sci*. **5** (10): 623–4. [doi](/source/Doi_(identifier)):[10.4103/1947-2714.120804](https://doi.org/10.4103%2F1947-2714.120804). [PMC](/source/PMC_(identifier)) [3842708](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842708). [PMID](/source/PMID_(identifier)) [24350079](https://pubmed.ncbi.nlm.nih.gov/24350079).

1. **[^](#cite_ref-9)** Peterson, Charles D. (1981). ["Oral ethanol doses in patients with methanol poisoning"](https://academic.oup.com/ajhp/article-abstract/38/7/1024/5200360). *American Journal of Health-System Pharmacy*. **38** (7): 1024–1027. [doi](/source/Doi_(identifier)):[10.1093/ajhp/38.7.1024](https://doi.org/10.1093%2Fajhp%2F38.7.1024).

1. **[^](#cite_ref-10)** [Methanol (CASRN 67-56-1)](http://www.epa.gov/iris/subst/0305.htm) [Archived](https://web.archive.org/web/20121205004930/http://www.epa.gov/iris/subst/0305.htm) 2012-12-05 at the [Wayback Machine](/source/Wayback_Machine)

1. **[^](#cite_ref-11)** ["Distillation: Some Purity Considerations"](http://www.moonshine-still.com/page7.htm). *Moonshine Still*. Retrieved 5 May 2015.

1. **[^](#cite_ref-12)** Blumenthal, P; Steger, MC; Einfalt, D; Rieke-Zapp, J; Quintanilla Bellucci, A; Sommerfeld, K; Schwarz, S; Lachenmeier, DW (28 April 2021). ["Methanol Mitigation during Manufacturing of Fruit Spirits with Special Consideration of Novel Coffee Cherry Spirits"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125215). *Molecules*. **26** (9): 2585. [doi](/source/Doi_(identifier)):[10.3390/molecules26092585](https://doi.org/10.3390%2Fmolecules26092585). [PMC](/source/PMC_(identifier)) [8125215](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125215). [PMID](/source/PMID_(identifier)) [33925245](https://pubmed.ncbi.nlm.nih.gov/33925245).

1. **[^](#cite_ref-13)** Hui-Ling Ma; Xiu-Ping Yang; Ying Zuo (15 April 2006). ["Study on Method of Decreasing Methanol in Apple Pomace Spirit"](http://www.spkx.net.cn/EN/abstract/abstract15544.shtml). *Food Science*. **27** (4): 138–142.

1. **[^](#cite_ref-14)** Wade, Leroy G. ["Physical properties of alcohols"](https://www.britannica.com/science/alcohol/Physical-properties-of-alcohols). *Britannica*. Retrieved 2024-08-18.

1. **[^](#cite_ref-15)** ["Resources - Promote and practice"](https://healthinfonet.ecu.edu.au/key-resources/resources/27191/?title=Metho++methylated+spirits+++It+s+not+a+drink+&contenttypeid=1&contentid=27191_1).

1. **[^](#cite_ref-16)** Isachenkov V (19 December 2016). ["Alcohol poisoning death toll in Russian city rises to 49"](https://www.apnews.com/c0c419587e7d44ec8a6c6ac2685b8f2a/Alcohol-poisoning-death-toll-in-Russian-city-rises-to-48). *[Associated Press](/source/Associated_Press)*. [Archived](https://web.archive.org/web/20161220183656/https://www.apnews.com/c0c419587e7d44ec8a6c6ac2685b8f2a/Alcohol-poisoning-death-toll-in-Russian-city-rises-to-48) from the original on 20 December 2016. Retrieved 19 December 2016.

1. **[^](#cite_ref-17)** Blum D (2010). *The Poisoner's Handbook: murder and the birth of forensic medicine in Jazz Age New York*. New York: Penguin Books. p. 231. [ISBN](/source/ISBN_(identifier)) [978-0-14-311882-4](https://en.wikipedia.org/wiki/Special:BookSources/978-0-14-311882-4).

1. **[^](#cite_ref-18)** ["Methanol poisoning cases from tainted alcohol in Jordan rise to 57, death toll stays at 9"](https://en.royanews.tv/news/60866). *Roya News*. 1 July 2025.

1. ^ [***a***](#cite_ref-Schep_19-0) [***b***](#cite_ref-Schep_19-1) [***c***](#cite_ref-Schep_19-2) [***d***](#cite_ref-Schep_19-3) [***e***](#cite_ref-Schep_19-4) Schep LJ, Slaughter RJ, Vale JA, Beasley DM (2009). ["A seaman with blindness and confusion"](http://www.bmj.com/cgi/content/full/339/sep30_1/b3929). *[BMJ](/source/BMJ)*. **339** b3929. [doi](/source/Doi_(identifier)):[10.1136/bmj.b3929](https://doi.org/10.1136%2Fbmj.b3929). [PMID](/source/PMID_(identifier)) [19793790](https://pubmed.ncbi.nlm.nih.gov/19793790). [S2CID](/source/S2CID_(identifier)) [6367081](https://api.semanticscholar.org/CorpusID:6367081). [Archived](https://web.archive.org/web/20091008081309/http://www.bmj.com/cgi/content/full/339/sep30_1/b3929) from the original on 2009-10-08.

1. **[^](#cite_ref-noCHOH_20-0)** McMartin KE, Martin-Amat G, Noker PE, Tephly TR (1979). "Lack of a role for formaldehyde in methanol poisoning in the monkey". *Biochem. Pharmacol*. **28** (5): 645–9. [doi](/source/Doi_(identifier)):[10.1016/0006-2952(79)90149-7](https://doi.org/10.1016%2F0006-2952%2879%2990149-7). [PMID](/source/PMID_(identifier)) [109089](https://pubmed.ncbi.nlm.nih.gov/109089).

1. **[^](#cite_ref-21)** Liesivuori J, Savolainen H (September 1991). "Methanol and formic acid toxicity: biochemical mechanisms". *Pharmacol. Toxicol*. **69** (3): 157–63. [doi](/source/Doi_(identifier)):[10.1111/j.1600-0773.1991.tb01290.x](https://doi.org/10.1111%2Fj.1600-0773.1991.tb01290.x). [PMID](/source/PMID_(identifier)) [1665561](https://pubmed.ncbi.nlm.nih.gov/1665561).

1. **[^](#cite_ref-22)** Casavant MJ (January 2001). ["Fomepizole in the treatment of poisoning"](http://pediatrics.aappublications.org/cgi/content/full/107/1/170). *Pediatrics*. **107** (1): 170. [doi](/source/Doi_(identifier)):[10.1542/peds.107.1.170](https://doi.org/10.1542%2Fpeds.107.1.170). [PMID](/source/PMID_(identifier)) [11134450](https://pubmed.ncbi.nlm.nih.gov/11134450). [Archived](https://web.archive.org/web/20050629084540/http://pediatrics.aappublications.org/cgi/content/full/107/1/170) from the original on 2005-06-29.

1. **[^](#cite_ref-Brent_23-0)** Brent J (May 2009). "Fomepizole for ethylene glycol and methanol poisoning". *The New England Journal of Medicine*. **360** (21): 2216–2223. [doi](/source/Doi_(identifier)):[10.1056/NEJMct0806112](https://doi.org/10.1056%2FNEJMct0806112). [PMID](/source/PMID_(identifier)) [19458366](https://pubmed.ncbi.nlm.nih.gov/19458366).

1. **[^](#cite_ref-24)** Voet D, Voet JG, Pratt CW (2008). *Fundamentals of Biochemistry: Life at the Molecular Level* (5th ed.). Hoboken, NJ: Wiley.

1. **[^](#cite_ref-25)** Blum D (2010). *The Poisoner's Handbook: murder and the birth of forensic medicine in Jazz Age New York*. New York: Penguin Books. p. 231. [ISBN](/source/ISBN_(identifier)) [978-0-14-311882-4](https://en.wikipedia.org/wiki/Special:BookSources/978-0-14-311882-4).

1. **[^](#cite_ref-26)** Isachenkov V (19 December 2016). ["Alcohol poisoning death toll in Russian city rises to 49"](https://www.apnews.com/c0c419587e7d44ec8a6c6ac2685b8f2a/Alcohol-poisoning-death-toll-in-Russian-city-rises-to-48). *[Associated Press](/source/Associated_Press)*. [Archived](https://web.archive.org/web/20161220183656/https://www.apnews.com/c0c419587e7d44ec8a6c6ac2685b8f2a/Alcohol-poisoning-death-toll-in-Russian-city-rises-to-48) from the original on 20 December 2016. Retrieved 19 December 2016.

1. **[^](#cite_ref-27)** Karimi, Nasser; Gambrell, Jon (27 March 2020). ["In Iran, false belief a poison fights virus kills hundreds"](https://web.archive.org/web/20200327084828/https://apnews.com/6e04783f95139b5f87a5febe28d72015). *Associated Press*. Archived from [the original](https://apnews.com/6e04783f95139b5f87a5febe28d72015) on 27 March 2020. Retrieved 27 March 2020.

1. **[^](#cite_ref-28)** ["FDA Updates on Hand Sanitizers with Methanol"](https://web.archive.org/web/20200706175026/https://www.fda.gov/drugs/drug-safety-and-availability/fda-updates-hand-sanitizers-methanol). *U.S. Food and Drug Administration*. Archived from [the original](https://www.fda.gov/drugs/drug-safety-and-availability/fda-updates-hand-sanitizers-methanol) on July 6, 2020. Retrieved 28 July 2020.

1. **[^](#cite_ref-29)** ["Methanol poisoning cases from tainted alcohol in Jordan rise to 57, death toll stays at 9"](https://en.royanews.tv/news/60866). *Roya News*. 1 July 2025.

1. **[^](#cite_ref-30)** ["Twelve charged with murder in Jordan's contaminated alcohol case"](https://en.royanews.tv/news/60872). *Roya News*. 1 July 2025.

## External links

Classification D ICD-10: T51.1 ICD-9-CM: E980.9

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Adapted from the Wikipedia article [Methanol toxicity](https://en.wikipedia.org/wiki/Methanol_toxicity) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Methanol_toxicity?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.