# MethBase

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/MethBase
> Markdown URL: https://mediated.wiki/source/MethBase.md
> Source: https://en.wikipedia.org/wiki/MethBase
> Source revision: 1314247379
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{onesource|date=May 2017}}
{{infobox biodatabase
|title = MethBase
|logo =File:Database.png
|description = Database for single [cytosine](/source/cytosine) resolution [DNA methylation](/source/DNA_methylation) data and associated annotations.
|scope =
|organism =Human<br/>Chimpanzee<br/>Gorilla<br/>Rhesus Macaque<br/>Mouse<br/>Arabidopsis
|center = 
|laboratory = Andrew D. Smith
|author = 
|citation = Qiang Song et al. (2013) <ref name="pmid24324667"/>
|released = 2013
|standard = 
|format = Trackhub on the [UCSC Genome Browser](/source/UCSC_Genome_Browser)
|url = http://smithlabresearch.org/software/methbase/
}}'''MethBase''' is a database of [DNA methylation](/source/DNA_methylation) data derived from [next-generation sequencing](/source/next-generation_sequencing) data.<ref name="pmid24324667">{{cite journal |last=Song|first=Qiang|author2=Decato Benjamin E |author3=Hong Elizabeth |author4=Zhou Meng |author5=Fang Fang |author6= Qu Jianghan |author7= Garvin Tyler |author8=Kessler Michael |author9= Zhou Jun |author10= Smith Andrew D |date=Dec 2013|title=A Reference Methylome Database and Analysis Pipeline to Facilitate Integrative and Comparative Epigenomics|journal = PLOS ONE|volume=8|issue=12|article-number=e81148| pmid = 24324667|doi = 10.1371/journal.pone.0081148| pmc = 3855694  |bibcode=2013PLoSO...881148S|doi-access=free}}</ref> MethBase provides a visualization of publicly available [bisulfite sequencing](/source/bisulfite_sequencing) and [reduced representation bisulfite sequencing](/source/reduced_representation_bisulfite_sequencing) experiments through the [UCSC Genome Browser](/source/UCSC_Genome_Browser).  MethBase contents include single-[CpG site](/source/CpG_site) resolution methylation levels for each CpG site in the [genome](/source/genome) of interest, annotation of regions of hypomethylation often associated with [gene promoters](/source/Promoter_(genetics)), and annotation of [allele](/source/allele)-specific methylation associated with [genomic imprinting](/source/genomic_imprinting).

==See also==
* [DNA methylation](/source/DNA_methylation)
* [MethDB](/source/MethDB)
* [NGSmethDB](/source/NGSmethDB)

==References==
<references/>

==External links==
* http://smithlabresearch.org/software/methbase

Category:Genetics databases
Category:Epigenetics
Category:DNA
Category:DNA sequencing

{{Biodatabase-stub}}

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Adapted from the Wikipedia article [MethBase](https://en.wikipedia.org/wiki/MethBase) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/MethBase?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.