# Metaphedrine

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Metaphedrine
> Markdown URL: https://mediated.wiki/source/Metaphedrine.md
> Source: https://en.wikipedia.org/wiki/Metaphedrine
> Source revision: 1352646952
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Short description|Designer drug}}
{{cs1 config|name-list-style=vanc|display-authors=6}}
{{Drugbox
| IUPAC_name = N-methyl-1-(3-methylphenyl)propan-2-amine
| image = 3-Methylmethamphetamine.svg
| image_class = skin-invert-image

<!--Clinical data-->
| tradename =

<!-- Legal status -->
| legal_DE = 
| legal_UK = 
| legal_US = [Schedule I (isomer of Etilamfetamime)](/source/List_of_Schedule_I_drugs_(US))

<!--Identifiers-->
| CAS_number = 861007-68-3
| PubChem = 24257262
| ChemSpiderID = 23900070
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ANT66P7LWF
| synonyms = 3-Methyl-''N''-methylamphetamine; 3-MMA; 3MMA; 3-Me-MA; Metaphedrine

<!--Chemical data-->
| C=11 | H=17 | N=1 
| smiles = CC1=CC(=CC=C1)CC(C)NC
| StdInChI = 1S/C11H17N/c1-9-5-4-6-11(7-9)8-10(2)12-3/h4-7,10,12H,8H2,1-3H3
| StdInChIKey = CXVNKBVJDKMLOH-UHFFFAOYSA-N
}}

'''Metaphedrine''',<ref>{{Cite web |date=March 4, 2026 |title=Metaphedrine - FDA Global Substance Registration System |url=https://precision.fda.gov/ginas/app/ui/substances/ANT66P7LWF |archive-url=https://web.archive.org/web/20260419052050/https://precision.fda.gov/ginas/app/ui/home |archive-date=April 19, 2026 |access-date=2026-04-19 |website=[Food and Drug Administration](/source/Food_and_Drug_Administration)}}</ref> or '''3-methylmethamphetamine''' ('''3-MMA'''), is a [methamphetamine](/source/methamphetamine) derivative which has been sold as a [designer drug](/source/designer_drug), with the substance first encountered online in 2020 and reported in [Sweden](/source/Sweden) in 2021.<ref>{{cite book | vauthors = ((European Monitoring Centre for Drugs and Drug Addiction.)) | title = New psychoactive substances: 25 years of early warning and response in Europe. An update from the EU Early Warning System | date = June 2022 | doi = 10.2810/882318 | url = https://www.emcdda.europa.eu/system/files/publications/14637/20222218_PDF_TD0522113ENN_002.pdf | publisher = European Monitoring Centre for Drugs and Drug Addiction | isbn = 978-92-9497-737-3 | doi-broken-date = 12 July 2025 }}</ref><ref name="Aipsin">{{cite web | title=3-MMA (3-Метилметамфетамин) | website=АИПСИН | url=https://aipsin.com/newsubstance/634/ | language=ru | access-date=1 January 2026}}</ref> It is a [potent](/source/potency_(pharmacology)) [monoamine reuptake inhibitor](/source/monoamine_reuptake_inhibitor)<ref name="Stalberga_2025">{{cite journal | vauthors = Stalberga D, Kronstrand R, Schranz B, van Zijl N, Karlman S, Aref S, Rautio T, Vikingsson S, Persson M, Gréen H | title = Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5HT2A receptor. | journal = Authorea | date = 2025 | doi = 10.22541/au.176253891.19158813/v1 }}</ref> and is thought to have [psychostimulant](/source/psychostimulant) effects.<ref name="Aipsin" /> The drug was not active as a [serotonin](/source/serotonin) [5-HT<sub>2A</sub> receptor](/source/5-HT2A_receptor) [agonist](/source/agonist).<ref name="Stalberga_2025" />

== See also ==
* [Substituted amphetamine](/source/Substituted_amphetamine)
* [3-Chloromethamphetamine](/source/3-Chloromethamphetamine)
* [3-Methoxymethamphetamine](/source/3-Methoxymethamphetamine)
* [3-Methylamphetamine](/source/3-Methylamphetamine)
* [3-Methylmethcathinone](/source/3-Methylmethcathinone)
* [3-Me-PVP](/source/3-Me-PVP)
* [4-Methylmethamphetamine](/source/4-Methylmethamphetamine)
* [Fenfluramine](/source/Fenfluramine)
* [3,4-Dimethylamphetamine](/source/Xylopropamine)

== References ==
{{Reflist}}

==External links==
* [https://isomerdesign.com/pihkal/explore/2947 3-Me-MA - Isomer Design]

{{Stimulants}}
{{Monoamine releasing agents}}
{{Phenethylamines}}

Category:Designer drugs
Category:Methamphetamines
Category:Methyl compounds
Category:Serotonin-norepinephrine-dopamine releasing agents
Category:Stimulants

{{Psychoactive-stub}}

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Adapted from the Wikipedia article [Metaphedrine](https://en.wikipedia.org/wiki/Metaphedrine) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Metaphedrine?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.