# Merrill Chase

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American immunologist (1905–2004)

Merrill Chase Portrait of Merrill Chase in the 1960s Born (1905-09-17)September 17, 1905 Providence, Rhode Island, U.S. Died January 5, 2004(2004-01-05) (aged 98) Alma mater Brown University Known for T cell, B cell Scientific career Fields Immunologist

**Merrill W. Chase** (September 17, 1905 – January 5, 2004) was an [immunologist](/source/Immunologist) working at [Rockefeller University](/source/Rockefeller_University) in New York City who is credited with discovering cell-mediated immunology in the early 1940s. While working with Dr. [Karl Landsteiner](/source/Karl_Landsteiner), Dr. Chase discovered that white blood cells, and not antibodies alone, were important instruments of the immune system. His findings laid the groundwork for later research that discovered the role of [B cells](/source/B_cells), [T cells](/source/T_cells) and other types of [white blood cells](/source/White_blood_cells).[1] Recognizing that other scientists were discovering multiple functions of the immune system, he established an independent Immunology laboratory at Rockefeller.[2]

## References

1. **[^](#cite_ref-1)** ["Merrill W. Chase, Scientist Who Advanced Immunology, Dies at 98"](https://www.nytimes.com/2004/01/22/nyregion/22CHAS.html), by Anahad O'Connor, January 22, 2004 *[New York Times](/source/New_York_Times)*, p. C15. Retrieved 24 June 2007

1. **[^](#cite_ref-2)** [Merrill W. Chase 1905–2004](http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/chase-merrill.pdf) [Archived](https://web.archive.org/web/20160321004920/http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/chase-merrill.pdf) 2016-03-21 at the [Wayback Machine](/source/Wayback_Machine)

- Chase, M W (1989). "Early days in cellular immunology". *Allergy and Asthma Proceedings*. **9** (6): 683–7. [doi](/source/Doi_(identifier)):[10.2500/108854188778965438](https://doi.org/10.2500%2F108854188778965438). [PMID](/source/PMID_(identifier)) [3066695](https://pubmed.ncbi.nlm.nih.gov/3066695).

- Chase, M W (1985). "Immunology and experimental dermatology". *Annu. Rev. Immunol*. **3**: 1–29. [doi](/source/Doi_(identifier)):[10.1146/annurev.iy.03.040185.000245](https://doi.org/10.1146%2Fannurev.iy.03.040185.000245). [PMID](/source/PMID_(identifier)) [3904768](https://pubmed.ncbi.nlm.nih.gov/3904768).

- Battisto, J R (1982). "Immunological tolerance to self and non-self. Opening remarks and appreciation". *Ann. N. Y. Acad. Sci*. **392** (1): ix–xi. [Bibcode](/source/Bibcode_(identifier)):[1982NYASA.392D...9B](https://ui.adsabs.harvard.edu/abs/1982NYASA.392D...9B). [doi](/source/Doi_(identifier)):[10.1111/j.1749-6632.1982.tb36092.x](https://doi.org/10.1111%2Fj.1749-6632.1982.tb36092.x). [PMID](/source/PMID_(identifier)) [6753688](https://pubmed.ncbi.nlm.nih.gov/6753688). [S2CID](/source/S2CID_(identifier)) [85233786](https://api.semanticscholar.org/CorpusID:85233786).

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