# LIN9

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/LIN9
> Markdown URL: https://mediated.wiki/source/LIN9.md
> Source: https://en.wikipedia.org/wiki/LIN9
> Source revision: 1301325350
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Lin-9 homolog''' is a [protein](/source/protein) that is encoded by the ''LIN9'' [gene](/source/gene) in humans.<ref name="pmid15538385">{{cite journal | vauthors = Gagrica S, Hauser S, Kolfschoten I, Osterloh L, Agami R, Gaubatz S | title = Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein | journal = The EMBO Journal | volume = 23 | issue = 23 | pages = 4627–38 | date = Nov 2004 | pmid = 15538385 | pmc = 533054 | doi = 10.1038/sj.emboj.7600470 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: LIN9 lin-9 homolog (C. elegans)| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=286826}}</ref>

== Interactions ==

LIN9 has been shown to [interact](/source/Protein-protein_interaction) with the [retinoblastoma protein](/source/retinoblastoma_protein).<ref name="pmid15538385"/>

== References ==
{{reflist}}

== Further reading ==
{{refbegin | 2}}
* {{cite journal | vauthors = Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA | title = Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 99 | issue = 26 | pages = 16899–903 | date = Dec 2002 | pmid = 12477932 | pmc = 139241 | doi = 10.1073/pnas.242603899 | bibcode = 2002PNAS...9916899M | doi-access = free }}
* {{cite journal | vauthors = Korenjak M, Taylor-Harding B, Binné UK, Satterlee JS, Stevaux O, Aasland R, White-Cooper H, Dyson N, Brehm A | title = Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes | journal = Cell | volume = 119 | issue = 2 | pages = 181–93 | date = Oct 2004 | pmid = 15479636 | doi = 10.1016/j.cell.2004.09.034 | doi-access = free }}
* {{cite journal | vauthors = Sandoval R, Xue J, Tian X, Barrett K, Pilkinton M, Ucker DS, Raychaudhuri P, Kineman RD, Luque RM, Baida G, Zou X, Valli VE, Cook JL, Kiyokawa H, Colamonici OR | title = A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes | journal = Experimental Cell Research | volume = 312 | issue = 13 | pages = 2465–75 | date = Aug 2006 | pmid = 16730350 | doi = 10.1016/j.yexcr.2006.04.002 }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = Nov 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}
* {{cite journal | vauthors = Pilkinton M, Sandoval R, Song J, Ness SA, Colamonici OR | title = Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1 | journal = The Journal of Biological Chemistry | volume = 282 | issue = 1 | pages = 168–75 | date = Jan 2007 | pmid = 17098733 | doi = 10.1074/jbc.M609924200 | doi-access = free }}
* {{cite journal | vauthors = Osterloh L, von Eyss B, Schmit F, Rein L, Hübner D, Samans B, Hauser S, Gaubatz S | title = The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis | journal = The EMBO Journal | volume = 26 | issue = 1 | pages = 144–57 | date = Jan 2007 | pmid = 17159899 | pmc = 1782375 | doi = 10.1038/sj.emboj.7601478 }}
* {{cite journal | vauthors = Pilkinton M, Sandoval R, Colamonici OR | title = Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex | journal = Oncogene | volume = 26 | issue = 54 | pages = 7535–43 | date = Nov 2007 | pmid = 17563750 | doi = 10.1038/sj.onc.1210562 | doi-access = free }}
{{refend}}

{{gene-1-stub}}

---
Adapted from the Wikipedia article [LIN9](https://en.wikipedia.org/wiki/LIN9) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/LIN9?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.