# Khusimol

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**Khusimol** is a [sesquiterpene](/source/Sesquiterpene) found in oil of [vetiver](/source/Vetiver). It contains a tricyclic hydrocarbon core, with a hydroxy methyl group, two [methyl groups](/source/Methyl_group) and a methylene group.[1] It constitutes the biggest part of oil of vetiver, around 15%.[2] The substance was initially discovered by D. C. Umarani in 1966 and separatated by using distillation and column chromatography.[2]

## References

1. Umarani, D.C.; Gore, K.G.; Chakravarti, K.K. (January 1966). "Terpenoids XC, Khusimol A New Sesquiterpene Alcohol". *Tetrahedron Letters*. **7** (12): 1255–1261. [doi:10.1016/S0040-4039(01)99704-7](https://doi.org/10.1016/S0040-4039(01)99704-7)

1. Rao, Renee C.; Gal, Claudine Serradeil-Le; Granger, Isabelle; Gleye, Jacqueline; Augereau, Jean-Michel; Bessibes, Cecile (October 1994). "Khusimol, a Non-Peptide Ligand for Vasopressin V1a Receptors". *Journal of Natural Products*. **57** (10): 1329–1335. [doi:10.1021/np50112a001](https://doi.org/10.1021/np50112a001). [PMID 7807119](https://pubmed.ncbi.nlm.nih.gov/7807119)

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