# Karsil

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**Karsil** (also called **erlüjixiancaoan**) is an [acylanilide](/source/Acylanilide) herbicide, similar to [propanil](/source/Propanil). It is potent against annual [grasses](/source/Grass) and broadleaved [weeds](/source/Weed) in [celery](/source/Celery), and a strong inhibitor of [photosynthesis](/source/Photosynthesis).[2] It is approved for use in [China](/source/China).[1]

When degraded by bacteria, karsil becomes [3,4-dichloroaniline](/source/3,4-dichloroaniline) and 3,3',4,4,'-tetrachloroazobenzene.[2] Karsil is theorised to form hydrogen bonds with the protein of an enzyme involved in the oxidation of water, creating its herbicidal potential, similar to [diuron](/source/Diuron) and [atrazine](/source/Atrazine).[3]

Karsil has been manufactured by Niagara Chemical Division.[4] If ingested, [activated charcoal](/source/Activated_charcoal) absorbs it.[5] Karsil is ten times as active as [atrazine](/source/Atrazine) at the [chloroplast](/source/Chloroplast) level.[6]

## References

1. ["erlujixiancaoan data sheet"](http://bcpcpesticidecompendium.org/erlujixiancaoan.html). *bcpcpesticidecompendium.org*

1. Sharabi, Nagim El-Din & Bordeleau, Lucien M. (September 1969). "Biochemical Decomposition of the Herbicide N-(3,4-Dichlorophenyl)-2-Methylpentanamide and Related Compounds". *Applied Microbiology*. **18** (3): 369–375. [doi:10.1128/am.18.3.369-375.1969](https://doi.org/10.1128/am.18.3.369-375.1969). [PMC 377987](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC377987). [PMID 5373674](https://pubmed.ncbi.nlm.nih.gov/5373674)

1. van Overbeek, J. (1962). "Physiological Responses of Plants to Herbicides". *Weeds*. **10** (3): 170–174. [doi:10.2307/4040775](https://doi.org/10.2307/4040775). [JSTOR 4040775](https://www.jstor.org/stable/4040775)

1. Wallnöfer, P. R.; Safe, S.; Hutzinger, O. (1 July 1972). "Die hydroxylation des herbizids karsil (N-(3,4-Dichlorophenyl)-2-methylpentanamid) durch Rhizopusjaponicus". *Chemosphere*. **1** (4): 155–158. [doi:10.1016/0045-6535(72)90019-7](https://doi.org/10.1016/0045-6535(72)90019-7)

1. ["Analytical reference standards and supplemental data for pesticides and other organic compounds"](https://nepis.epa.gov/Exe/ZyPURL.cgi?Dockey=9101PT4X.txt). *nepis.epa.gov*. January 1981.

1. Masatoshi, Ghobara; Duke, Stephen O.; Takematsu, Tetsuo (August 26, 1987). ["MT-5950, a New Anilide Herbicide, Inhibits PSII at a Site that Slightly Overlaps the Triazine Binding Site"](https://www.jstage.jst.go.jp/article/bbb1961/52/2/52_2_465/_pdf). *Agric. Biol. Chem.*. Retrieved 15 March 2025.

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