# Inhalation

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{{short description|Flow of the respiratory current into an organism}}
{{More citations needed|date=March 2020}}
{{redirect|Inhale|the 2013 Marsheaux album|Inhale (album)}}
thumb|Diagram showing inhalation
'''Inhalation''' (or '''inspiration''') happens when air or other gases enter the lungs.

== Inhalation of air ==
Inhalation of air, as part of the cycle of [breathing](/source/breathing), is a vital process for all human life. The process is autonomic (though there are exceptions in some disease states) and does not need conscious [control](/source/Control_of_ventilation) or effort. However, breathing can be consciously controlled or interrupted (within limits).

Breathing allows oxygen (which humans and a lot of other species need for survival) to enter the lungs, from where it can be absorbed into the bloodstream.

== Other substances – accidental ==
Examples of accidental inhalation includes inhalation of water (e.g. in drowning), smoke, food, vomitus and less common foreign substances<ref>{{Cite journal|last2=Lauriello|first2=M|last3=Bellussi|first3=L|last4=Passali|first4=GC|last5=Passali|first5=FM|last6=Gregori|first6=D|date=2010|title=Foreign body inhalation in children: an update|pmc=2881610|journal=Acta Otorhinolaryngol Ital|pmid=20559470|last1=Passàli|first1=D|volume=30|issue=1|pages=27–32}}</ref> (e.g. tooth fragments, coins, batteries, small toy parts, needles).

== Other substances – deliberate ==

=== Recreational use ===
[Nitrous oxide](/source/Nitrous_oxide) ("laughing gas") has been [used recreationally since 1899](/source/Recreational_use_of_nitrous_oxide) for its ability to induce [euphoria](/source/euphoria), [hallucinogenic](/source/hallucinogenic) states and [relaxation](/source/Relaxation_(psychology)), and is legal in some countries.

[Helium](/source/Helium) can be inhaled to give the voice a reedy, duck-like quality, but this can be dangerous as the gas is an [asphyxiant](/source/asphyxiant_gas) and displaces the oxygen needed for normal respiration.<ref name="Grass">{{Cite journal| title = Suicidal asphyxiation with helium: Report of three cases Suizid mit Helium Gas: Bericht über drei Fälle| journal = Wiener Klinische Wochenschrift| volume = 119|issue =9–10|date = 2007|doi = 10.1007/s00508-007-0785-4|author = Grassberger, Martin|author2 = Krauskopf, Astrid |pages = 323–325 |language=de, en| pmid = 17571238|s2cid = 22894287}}</ref> 

Various illegal gaseous, vapourised  or aerosolized [recreational drugs](/source/recreational_drugs) exist, and are classed as [inhalant](/source/inhalant)s.

=== Medical use ===

==== Diagnostic ====

Various specialized investigations use the inhalation of known substances for diagnostic purposes. Examples include [pulmonary function testing](/source/pulmonary_function_testing) (e.g. [nitrogen washout](/source/nitrogen_washout) test, [diffusion capacity](/source/Diffusing_capacity) testing ([carbon monoxide](/source/carbon_monoxide), [helium](/source/helium), [methane](/source/methane))) and [diagnostic radiology](/source/diagnostic_radiology) (e.g. [radioactive xenon isotopes](/source/Isotopes_of_xenon)).

==== Therapeutic ====

Gases and other drugs used in anaesthesia include oxygen, nitrous oxide, helium, xenon, [volatile anaesthetic agents](/source/Inhalational_anaesthetic). Medication for [asthma](/source/asthma), croup, cystic fibrosis and some other conditions.

== Mechanism ==
Inhalation begins with the contraction of the muscles attached to the rib cage; this causes an expansion in the chest cavity.  Then takes place the onset of contraction of the [thoracic diaphragm](/source/thoracic_diaphragm), which results in expansion of the [intrapleural space](/source/intrapleural_space) and an increase in negative pressure according to [Boyle's law](/source/Boyle's_law).  This negative pressure generates airflow because of the pressure difference between the atmosphere and alveolus. 

The inflow of air into the lungs occurs via the [respiratory airways](/source/respiratory_airways). In health, these airways [begin with the nose](/source/Obligate_nasal_breathing).<ref name=cc>{{cite web
|url=https://health.clevelandclinic.org/breathe-mouth-nose/
|title=Should You Breathe Through Your Mouth or Your Nose?
|access-date=2020-06-28
|last=Turowski
|first=Jason
|date=2016-04-29
|publisher=[Cleveland Clinic](/source/Cleveland_Clinic)
}}</ref><ref name="guardian">{{cite web|title=Your Nose, the Guardian of Your Lungs|url=https://www.bmc.org/otolaryngology-head-neck-surgery/resources/your-nose-guardian-your-lungs|access-date=2020-06-29|publisher=[Boston Medical Center](/source/Boston_Medical_Center)}}</ref> It is possible to begin with the mouth, which is the backup breathing system. However, chronic [mouth breathing](/source/mouth_breathing) leads to, or is a sign of, illness, and there is no mucus in the mouth to trap unwanted substances unlike the nostrils.<ref name=harmful>{{cite web
|url=https://www.nbcnews.com/healthmain/mouth-breathing-gross-harmful-your-health-1C6437430
|title='Mouth-breathing' gross, harmful to your health
|access-date=2020-06-28
|last=Dahl
|first=Melissa
|date=2011-01-11
|publisher=NBC News
}}</ref><ref name="role">{{cite web
|url=https://www.journal-imab-bg.org/issues-2018/issue1/JofIMAB-2018-24-1p1878-1882.pdf
|title=THE ROLE OF MOUTH BREATHING ON DENTITION DEVELOPMENT AND FORMATION
|access-date=2020-05-31
|last=Valcheva
|first=Zornitsa
|date=January 2018
|publisher=Journal of IMAB
}}</ref><ref name="nesnpr">{{cite web
|url=https://www.npr.org/transcripts/862963172
|title=How The 'Lost Art' Of Breathing Can Impact Sleep And Resilience
|access-date=2020-06-23
|last=Gross
|first=Terry
|date=2020-05-27
|publisher=[National Public Radio (NPR)](/source/NPR)/[Fresh Air](/source/Fresh_Air)
}}</ref> They end in the microscopic dead-end sacs ([alveoli](/source/Pulmonary_alveolus)) always opened, though the diameters of the various sections can be changed by the [sympathetic](/source/Sympathetic_nervous_system) and [parasympathetic nervous system](/source/parasympathetic_nervous_system)s. The alveolar air pressure is therefore always close to atmospheric air pressure (about 100&nbsp;[kPa](/source/Pascal_(unit)) at sea level) at rest, with the pressure gradients that cause air to move in and out of the lungs during breathing rarely exceeding 2–3&nbsp;kPa.<ref name="Chrisvan L 1995">{{cite journal |last1=Koen |first1=Chrisvan L. |last2=Koeslag |first2=Johan H. | title=On the stability of subatmospheric intrapleural and intracranial pressures |journal= News in Physiological Sciences | date=1995 |volume=10 |issue=4 |pages=176–178 |doi=10.1152/physiologyonline.1995.10.4.176}}</ref><ref name="Williams & Wilkins">{{cite book |last1=West |first1=J.B. |title=Respiratory physiology: the essentials. |location=Baltimore |publisher=Williams & Wilkins |date=1985| pages= 21–30, 84–84, 98–101 }}</ref>

Other muscles that can be involved in inhalation include:<ref>{{cite book| title= Essentials of Human Physiology| first= Thomas M. |last= Nosek| chapter=Section 4/4ch2/s4ch2_10 |chapter-url=http://humanphysiology.tuars.com/program/section4/4ch2/s4ch2_10.htm |archive-url=https://web.archive.org/web/20160324124828/http://humanphysiology.tuars.com/program/section4/4ch2/s4ch2_10.htm|archive-date=2016-03-24}}</ref>
* [External intercostal muscles](/source/External_intercostal_muscles)
* [Scalene muscles](/source/Scalene_muscles)
* [Sternocleidomastoid muscle](/source/Sternocleidomastoid_muscle)
* [Trapezius muscle](/source/Trapezius_muscle)

==Hyperinflation==
{{For-multi|another similar term|Dynamic hyperinflation|the Economics term|Hyperinflation}}

''Hyperinflation'' or ''hyperaeration'' is where the lung volume is abnormally increased, with increased filling of the alveoli. This results in an increased [radiolucency](/source/radiodensity) on X-ray, a reduction in lung markings and depression of the diaphragm. It may occur in partial obstruction of a large airway, as in e.g. [congenital lobar emphysema](/source/congenital_lobar_emphysema), bronchial [atresia](/source/atresia) and mucus plugs in [asthma](/source/asthma).<ref>{{cite web|url=http://www.medcyclopaedia.com/library/topics/volume_vii/h/hyperinflation.aspx|archive-url=https://archive.today/20111208222639/http://www.medcyclopaedia.com/library/topics/volume_vii/h/hyperinflation.aspx|url-status=dead|archive-date=2011-12-08|title=Hyperinflation|publisher=[GE](/source/General_Electric)|work=Medcyclopaedia}}</ref>

==Yoga==
Yogis such as [B. K. S. Iyengar](/source/B._K._S._Iyengar) advocate both [inhaling and exhaling through the nose](/source/Obligate_nasal_breathing) in the practice of [yoga](/source/yoga), rather than inhaling through the nose and [exhaling through the mouth](/source/Mouth_breathing).<ref name=yj>{{cite web
|url=https://www.yogajournal.com/practice/take-a-breath
|title=Q&A: Is Mouth Breathing OK in Yoga?
|access-date=2020-06-26
|date=2017-04-12
|publisher=[Yoga Journal](/source/Yoga_Journal)
}}</ref><ref name=dummies>{{cite web
|url=https://www.dummies.com/health/exercise/yoga/yogic-breathing-tips-for-breathing-through-your-nose-most-of-the-time/
|title=Yogic Breathing: Tips for Breathing through Your Nose (Most of the Time)
|access-date=2020-06-26
|last=Payne
|first=Larry
|publisher=[Yoga For Dummies, 3rd Edition](/source/For_Dummies)
}}</ref><ref name=guide>{{cite web
|url=https://www.himalayaninstitute.org/wisdom-library/yogic-breathing-study-guide/
|title=Yogic Breathing: A Study Guide
|access-date=2020-06-26
|last=Himalayan Institute Core Faculty
|first=Himalayan Institute Core Faculty
|date=2017-07-13
|publisher=[Himalayan Institute of Yoga Science and Philosophy](/source/Himalayan_Institute_of_Yoga_Science_and_Philosophy)
}}</ref> They tell their students that the "nose is for breathing, the mouth is for eating."<ref name=dummies/><ref name=sparks>{{cite book
|url=https://books.google.com/books?id=QPk_nshsngoC&q=%22the+nose+is+for+breathing%2C+the+mouth+is+for+eating%22+yoga&pg=RA1-PA11
|title=Yoga Sparks
|access-date=2020-05-31
|last=Krucoff
|first=Carol
|date=2013
|publisher=New Harbinger Publications
|isbn=9781608827022
}}</ref><ref name=run>{{cite book
|url=https://books.google.com/books?id=fEm6XnTajm0C&q=%22the+nose+is+for+breathing%2C+the+mouth+is+for+eating%22+yoga&pg=PA108
|title=Eat and Run
|access-date=2020-05-31
|last=Jurek
|first=Scott
|date=2012
|publisher=Houghton Mifflin
|isbn=978-0547569659
}}</ref><ref name=yj/>

==See also==
{{Wiktionary|inhalation|sniffing}}
* [Exhalation](/source/Exhalation)
* [Inhalant](/source/Inhalant) – psychoactive drugs consumed through inhalation
* [List of terms of lung size and activity](/source/List_of_terms_of_lung_size_and_activity)
* [Mouth breathing](/source/Mouth_breathing)
* [Obligate nasal breathing](/source/Obligate_nasal_breathing)
* [Respiratory system](/source/Respiratory_system)
* [Smoking](/source/Smoking) - a specific inhalation route
* [Breathing](/source/Breathing)
* [Work of breathing](/source/Work_of_breathing)

==Further reading==
* {{Cite book|title=[Breath: The New Science of a Lost Art](/source/Breath%3A_The_New_Science_of_a_Lost_Art)
|last=Nestor|first=James|publisher=Riverhead Books |year=2020|isbn= 978-0735213616 }}

==References==
{{reflist}}

{{Dosage forms}}
{{Respiratory physiology}}

Category:Respiration
Category:Respiratory physiology

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Adapted from the Wikipedia article [Inhalation](https://en.wikipedia.org/wiki/Inhalation) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Inhalation?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.
