# HS6ST2

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/HS6ST2
> Markdown URL: https://mediated.wiki/source/HS6ST2.md
> Source: https://en.wikipedia.org/wiki/HS6ST2
> Source revision: 1079538797
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}

'''Heparan sulfate 6-O-sulfotransferase 2''' is a [protein](/source/protein) that in humans is encoded by the HS6ST2 [gene](/source/gene).
<ref name="entrez">
{{cite web
| title = Entrez Gene: Heparan sulfate 6-O-sulfotransferase 2
| url = https://www.ncbi.nlm.nih.gov/gene/90161
| access-date = 2016-07-11
}}</ref>

==Function==

[Heparan sulfate](/source/Heparan_sulfate) proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various [ligands](/source/Ligand) to influence [cell growth](/source/cell_growth), differentiation, adhesion, and migration. 

This gene encodes a member of the heparan sulfate (HS) [sulfotransferase](/source/sulfotransferase) gene family, which catalyze the transfer of [sulfate](/source/sulfate) to HS. Different family members and [isoforms](/source/isoforms) are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene.

== References ==

{{reflist}}

== Further reading ==

{{refbegin | 2}}
*{{cite journal |vauthors=Habuchi H, Miyake G, Nogami K, Kuroiwa A, Matsuda Y, Kusche-Gullberg M, Habuchi O, Tanaka M, Kimata K |title=Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties |journal=Biochem. J. |volume=371 |issue=Pt 1 |pages=131–42 |year=2003 |pmid=12492399 |pmc=1223259 |doi=10.1042/BJ20021259 }}

{{refend}}

{{NLM content}}

{{gene-X-stub}}

---
Adapted from the Wikipedia article [HS6ST2](https://en.wikipedia.org/wiki/HS6ST2) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/HS6ST2?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.