# GABAergic

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{{short description|Affecting GABA systems in the brain}}
In [molecular biology](/source/molecular_biology) and physiology, something is '''GABAergic''' or '''GABAnergic''' if it pertains to or affects the neurotransmitter [gamma-aminobutyric acid](/source/%CE%93-Aminobutyric_acid) (GABA). For example, a [synapse](/source/synapse) is GABAergic if it uses GABA as its [neurotransmitter](/source/neurotransmitter), and a GABAergic [neuron](/source/neuron) produces GABA. A substance is GABAergic if it produces its effects via interactions with the [GABA system](/source/GABA_system), such as by stimulating or [blocking](/source/Ganglionic_blocker) neurotransmission.

A GABAergic or GABAnergic agent is any chemical that modifies the effects of GABA in the body or brain. Some different classes of GABAergic drugs include [agonists](/source/GABA_receptor_agonist), [antagonists](/source/GABA_receptor_antagonist), modulators, reuptake inhibitors and enzymes.<ref name="Froestl2011">{{cite journal|last1=Froestl|first1=Wolfgang|title=An historical perspective on GABAergic drugs|journal=[Future Medicinal Chemistry](/source/Future_Medicinal_Chemistry)|volume=3|issue=2|year=2011|pages=163–175|issn=1756-8919|doi=10.4155/fmc.10.285|pmid=21428811}}</ref>

==See also==
* [Adenosinergic](/source/Adenosinergic)
* [Adrenergic](/source/Adrenergic)
* [Cannabinoidergic](/source/Cannabinoidergic)
* [Cholinergic](/source/Cholinergic)
* [Dopaminergic](/source/Dopaminergic)
* [Glutamatergic](/source/Glutamatergic)
* [Glycinergic](/source/Glycinergic)
* [Histaminergic](/source/Histaminergic)
* [Melatonergic](/source/Melatonergic)
* [Monoaminergic](/source/Monoaminergic)
* [Neurotransmission](/source/Monoaminergic)
* [Opioidergic](/source/Opioidergic)
* [Serotonergic](/source/Serotonin)

==References==
{{Reflist}}

{{GABA receptor modulators}}
{{GABAA receptor positive allosteric modulators}}
{{GABA metabolism and transport modulators}}
{{Neuromodulation}}

Category:Neurotransmitters

{{nervous-system-drug-stub}}

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Adapted from the Wikipedia article [GABAergic](https://en.wikipedia.org/wiki/GABAergic) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/GABAergic?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.