# Fluocortolone

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Fluocortolone
> Markdown URL: https://mediated.wiki/source/Fluocortolone.md
> Source: https://en.wikipedia.org/wiki/Fluocortolone
> Source revision: 1330279365
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Short description|Chemical compound}}
{{Distinguish|Fluclorolone|Fluocortin}}
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 461101617
| IUPAC_name = (1''S'',2''R'',8''S'',10''S'',11''S'',13''R'',14''S'',15''S'',17''S'')-8-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0<sup>2,7</sup>.0<sup>11,15</sup>]heptadeca-3,6-dien-5-one
| image = Fluocortolone skeletal.svg
| image_class = skin-invert-image

<!--Clinical data-->
| tradename =  
| Drugs.com = 
| pregnancy_category =  
| legal_status =  
| routes_of_administration = Ointment, suppositories

<!--Pharmacokinetic data-->
| bioavailability =  
| metabolism =  
| excretion =  

<!--Identifiers-->
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 152-97-6
| ATC_prefix = C05
| ATC_suffix = AA08
| ATC_supplemental = {{ATC|D07|AC05}} {{ATC|H02|AB03}}
| PubChem = 9053
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB08971
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 8701
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 65VXC1MH0J
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D04218
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 251634

<!--Chemical data-->
| C=22 | H=29 | F=1 | O=4 
| smiles = O=C\1\C=C/[C@]4(/C(=C/1)[C@@H](F)C[C@@H]2[C@@H]4[C@@H](O)C[C@@]3([C@@H](C(=O)CO)[C@@H](C[C@@H]23)C)C)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C22H29FO4/c1-11-6-14-13-8-16(23)15-7-12(25)4-5-21(15,2)20(13)17(26)9-22(14,3)19(11)18(27)10-24/h4-5,7,11,13-14,16-17,19-20,24,26H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19-,20-,21+,22+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = GAKMQHDJQHZUTJ-ULHLPKEOSA-N
| synonyms = <small>(6''S'',8''S'',9''R'',10''S'',11''S'',13''S'',14''S'',16''R'',17''S'')-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[''a'']phenanthren-3-one</small>
}}

'''Fluocortolone''' is a [glucocorticoid](/source/glucocorticoid)<ref name="pmid6054003">{{cite journal | vauthors = Munro DD, Wilson HT, Rhodes EL | title = Comparison of betamethasone 17-valerate ointment with fluocortolone and fluocortolone caproate ointment | journal = British Medical Journal | volume = 4 | issue = 5574 | pages = 275–6 | date = November 1967 | pmid = 6054003 | pmc = 1748932 | doi = 10.1136/bmj.4.5574.275 }}</ref> used in the treatment of several conditions, including [hemorrhoid](/source/hemorrhoid)s.

It is similar to [fluocortin](/source/fluocortin), but with one less [carbonyl group](/source/carbonyl_group).

==See also==
* [Corticosteroids](/source/Corticosteroids)

==References==
{{Reflist}}

{{Glucocorticoids}}
{{Vasoprotectives}}
{{Glucocorticoidics}}

Category:Glucocorticoids
Category:Organofluorides

{{systemic-hormonal-drug-stub}}
{{cardiovascular-drug-stub}}
{{dermatologic-drug-stub}}

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Adapted from the Wikipedia article [Fluocortolone](https://en.wikipedia.org/wiki/Fluocortolone) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Fluocortolone?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.