# Filtration coefficient

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Net filtration pressure in glomerulus of the kidney

In physiology, **filtration coefficient** (**Kf**) is the product of a biological membrane's permeability to water and the surface area of the membrane. Typical units of Kf are mL/min/mmHg. The rate of filtration across the membrane is, by definition, the product of Kf and the net filtration pressure across the membrane.[1][2][3] Kf is frequently applied to the glomerular capillaries, which filter water into Bowman's capsule to form urine. Typically, in an adult human, the net filtration pressure is 10mmHg and Kf 12.5mL/min/mmHg, giving a glomerular filtration rate (GFR) of 125mL/min. A decrease in Kf due to reduced number of glomeruli or reduced permeability will reduce the GFR at a given filtration pressure[3]

## References

1. **[^](#cite_ref-1)** ["Filtration coefficient - definition of filtration coefficient by Medical dictionary"](http://medical-dictionary.thefreedictionary.com/filtration+coefficient). *TheFreeDictionary.com*. Retrieved 27 December 2016.

1. **[^](#cite_ref-2)** ["Glomerular filtration rate"](http://www.ld99.com/reference/old/text/2878909-442.html). Retrieved 27 December 2016.

1. ^ [***a***](#cite_ref-book1_3-0) [***b***](#cite_ref-book1_3-1) E. Hall, John (2011). *Guyton and Hall Textbook of Medical Physiology/12th ed*. United States of America. p. 181. [ISBN](/source/ISBN_(identifier)) [978-1-4160-4574-8](https://en.wikipedia.org/wiki/Special:BookSources/978-1-4160-4574-8).{{[cite book](https://en.wikipedia.org/wiki/Template:Cite_book)}}: CS1 maint: location missing publisher ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_location_missing_publisher))

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