# FXYD6

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> Source: https://en.wikipedia.org/wiki/FXYD6
> Source revision: 910922905
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{{infobox protein
|Name=FXYD domain containing ion transport regulator 6
|caption=
|image=
|width=
|HGNCid=4030
|Symbol=FXYD6
|AltSymbols=
|EntrezGene=53826
|OMIM=606683
|RefSeq=NM_022003
|UniProt=Q9H0Q3
|PDB=
|ECnumber=
|Chromosome=11
|Arm=q
|Band=23.3
|LocusSupplementaryData=
}}
'''FXYD6''' (pronounced fix-id six), or FXYD domain-containing ion transport regulator 6, is a [gene](/source/gene) which is located at the 11q23.3 ([chromosome 11](/source/chromosome_11) locus 23.3).  The FXYD6 protein contains 95 [amino acids](/source/amino_acids), and can be found in all human tissues except blood.

This gene belongs to the [FXYD family](/source/FXYD_family) of [ion transport regulator](/source/ion_transport_regulator)s <ref>[http://www.sanger.ac.uk/cgi-bin/Pfam/getacc?PF02038 ATP1G1/PLM/MAT8 family in PFAM]{{Dead link|date=August 2019 |bot=InternetArchiveBot |fix-attempted=yes }}</ref>

==Pathology==
According to recent research, mutations in the FXYD6 gene, or in sequences close by this gene, can predispose to the [schizophrenia](/source/schizophrenia) which is known to be strongly heritable.<ref>[http://www.schizophreniaforum.org/new/detail.asp?id=1326  Getting Crowded on Chromosome 11q22—Make Way for Phosphohippolin] {{webarchive |url=https://web.archive.org/web/20070430235133/http://www.schizophreniaforum.org/new/detail.asp?id=1326 |date=April 30, 2007 }}</ref><ref>{{cite journal |vauthors=Choudhury K, McQuillin A, Puri V |title=A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia |journal=Am. J. Hum. Genet. |volume=80 |issue=4 |pages=664–72 |year=2007 |pmid=17357072 |doi=10.1086/513475 |pmc=1852702|display-authors=etal}}</ref>

==References==
{{reflist}}

== External links ==
*[https://www.genecards.org/cgi-bin/carddisp.pl?gene=FXYD6 GeneCards page about the gene]

Category:Genes on human chromosome 11
Category:Transmembrane proteins

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Adapted from the Wikipedia article [FXYD6](https://en.wikipedia.org/wiki/FXYD6) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/FXYD6?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.