# Expression Atlas > Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Expression_Atlas > Markdown URL: https://mediated.wiki/source/Expression_Atlas.md > Source: https://en.wikipedia.org/wiki/Expression_Atlas > Source revision: 1257718226 > License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) {{Short description|Gene expression database}} {{infobox biodatabase |logo = |title = '''Expression Atlas''' |description = Gene expression across species and conditions |scope = Microarray Data and other Gene Expression |organism = Human, Mouse, Rat, Fruit-fly, Chicken, Roundworm, Wild boar, Zebrafish, Cow and others. |center = [EMBL-EBI](/source/EMBL-EBI) |pmid = 31665515 |released = March 2020 |url = {{URL|www.ebi.ac.uk/gxa/home}} |download = |webapp = Advanced search, bulk retrieval/download |versioning = |frequency = [https://www.ebi.ac.uk/gxa/release-notes.html 3 to 4 times a year] |curation = Manual curation of every study. |bookmark = |version = }} The '''Expression Atlas''' is a [database](/source/biological_database) maintained by the [European Bioinformatics Institute](/source/European_Bioinformatics_Institute) that provides information on [gene expression](/source/gene_expression) patterns from [RNA-Seq](/source/RNA-Seq) and [Microarray](/source/DNA_microarray) studies, and protein expression from [Proteomics](/source/Proteomics) studies.{{cite journal | vauthors = Papatheodorou I, Moreno P, Manning J, Fuentes AM, George N, Fexova S, Fonseca NA, Füllgrabe A, Green M, Huang N, Huerta L, Iqbal H, Jianu M, Mohammed S, Zhao L, Jarnuczak AF, Jupp S, Marioni J, Meyer K, Petryszak R, Prada Medina CA, Talavera-López C, Teichmann S, Vizcaino JA, Brazma A | display-authors = 6 | title = Expression Atlas update: from tissues to single cells | journal = Nucleic Acids Research | volume = 48 | issue = D1 | pages = D77–D83 | date = Jan 2020 | pmid = 31665515 | doi = 10.1093/nar/gkz947 | pmc = 7145605 | doi-access = free }} The Expression Atlas allows searches by [gene](/source/gene), [splice variant](/source/Alternative_splicing), protein attribute, disease, treatment or organism part (cell types/tissues). Individual genes or gene sets can be searched for. All datasets in Expression Atlas have its metadata manually curated and its data analysed through standardised analysis pipelines. There are two components to the Expression Atlas, the Baseline Atlas and the Differential Atlas: == Baseline Atlas == The Baseline Atlas provides information about which [gene product](/source/gene_product)s are present (and at what abundance) under "normal" conditions. This component of the Expression Atlas consists of [RNA-seq](/source/RNA-Seq) experiments from ArrayExpress repositories. It aims to answer questions such as: * Which genes are specifically expressed in kidney? * What is the expression pattern for gene [SAA4](/source/SAA4) in normal tissues? == Differential Atlas == The Differential Atlas allows users to identify genes that are up- or down-regulated in different experimental conditions. == See also == * [Human Protein Atlas](/source/Human_Protein_Atlas) * [The Cancer Genome Atlas](/source/The_Cancer_Genome_Atlas) == References == {{reflist}} == Further reading == {{refbegin}} * {{cite journal | vauthors = Petryszak R, Burdett T, Fiorelli B, Fonseca NA, Gonzalez-Porta M, Hastings E, Huber W, Jupp S, Keays M, Kryvych N, McMurry J, Marioni JC, Malone J, Megy K, Rustici G, Tang AY, Taubert J, Williams E, Mannion O, Parkinson HE, Brazma A | display-authors = 6 | title = Expression Atlas update--a database of gene and transcript expression from microarray- and sequencing-based functional genomics experiments | journal = Nucleic Acids Research | volume = 42 | issue = Database issue | pages = D926-32 | date = January 2014 | pmid = 24304889 | doi = 10.1093/nar/gkt1270 | publisher = Oxford University Press (OUP) | pmc = 3964963 | doi-access = free }} * {{cite journal | vauthors = Kapushesky M, Adamusiak T, Burdett T, Culhane A, Farne A, Filippov A, Holloway E, Klebanov A, Kryvych N, Kurbatova N, Kurnosov P, Malone J, Melnichuk O, Petryszak R, Pultsin N, Rustici G, Tikhonov A, Travillian RS, Williams E, Zorin A, Parkinson H, Brazma A | display-authors = 6 | title = Gene Expression Atlas update--a value-added database of microarray and sequencing-based functional genomics experiments | journal = Nucleic Acids Research | volume = 40 | issue = Database issue | pages = D1077-81 | date = January 2012 | pmid = 22064864 | doi = 10.1093/nar/gkr913 | publisher = Oxford University Press (OUP) | pmc = 3245177 | doi-access = free }} {{refend}} == External links == * {{cite web | title = About Expression Atlas | url = http://www.ebi.ac.uk/gxa/about.html | publisher = European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI) }} Category:Genetics databases Category:Genomics Category:Open science Category:Science and technology in Cambridgeshire Category:South Cambridgeshire District --- Adapted from the Wikipedia article [Expression Atlas](https://en.wikipedia.org/wiki/Expression_Atlas) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Expression_Atlas?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.