# DnaE

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/DnaE
> Markdown URL: https://mediated.wiki/source/DnaE.md
> Source: https://en.wikipedia.org/wiki/DnaE
> Source revision: 1040895937
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Infobox nonhuman protein
| Name = DNA pol III alpha subunit aka DNA Enus
| image = 
| width = 
| caption = 
| Organism = ''[Escherichia coli](/source/Escherichia_coli)''<br/>(str. K-12 substr. MG1655)
| TaxID = 511145
| Symbol = dnaE
| AltSymbols = 
| EntrezGene = 944877
| PDB = 2HNH 
| RefSeqmRNA = 
| RefSeqProtein =NP_414726.1
| UniProt = P10443
| ECnumber = 2.7.7.7
| Chromosome = genome
| EntrezChromosome = NC_000913.2
| GenLoc_start = 204603
| GenLoc_end = 209129
}}
{{Infobox protein family
| Symbol = DNA_pol3_alpha
| Name = Bacterial DNA polymerase III alpha subunit
| image = 
| width = 
| caption = crystal structure of the catalytic alpha subunit of e. coli replicative dna polymerase iii
| Pfam = PF07733
| Pfam_clan =  
| InterPro = IPR011708
| SMART = 
| PROSITE = 
| MEROPS = 
| SCOP = 
| TCDB = 
| OPM family = 
| OPM protein = 
| CAZy = 
| CDD = 
}}

'''DnaE''', the [gene product](/source/gene_product) of '''''dnaE''''', is the catalytic α subunit of [DNA polymerase III](/source/DNA_polymerase_III), acting as a DNA [polymerase](/source/DNA_polymerase). This [enzyme](/source/enzyme) is only found in [prokaryotes](/source/prokaryotes).<ref>{{cite journal | vauthors = Wu H, Hu Z, Liu XQ | title = Protein trans-splicing by a split intein encoded in a split DnaE gene of Synechocystis sp. PCC6803 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 16 | pages = 9226–31 | date = August 1998 | pmid = 9689062 | pmc = 21320 | doi = 10.1073/pnas.95.16.9226 | doi-access = free }}</ref>

== References ==
{{reflist}}

{{DNA replication}}

Category:Bacterial proteins
Category:DNA replication

{{molecular-biology-stub}}

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Adapted from the Wikipedia article [DnaE](https://en.wikipedia.org/wiki/DnaE) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/DnaE?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.