# Dimaprit

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Dimaprit
> Markdown URL: https://mediated.wiki/source/Dimaprit.md
> Source: https://en.wikipedia.org/wiki/Dimaprit
> Source revision: 1311013388
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 360226931
| ImageFile = Dimaprit.svg
| ImageSize = 222
| PIN = 3-(Dimethylamino)propyl carbamimidothioate
| OtherNames = 3-dimethylaminopropyl sulfanylmethanimidamide

| Section1 = {{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 65119-89-3
| PubChem = 3077
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 12344
| IUPHAR_ligand = 1248
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = ZZQ699148P
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = C17930
| SMILES = CN(C)CCCSC(=N)N
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 2968
| InChI = 1/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8)
| InChIKey = OLHQOJYVQUNWPL-UHFFFAOYAQ
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = OLHQOJYVQUNWPL-UHFFFAOYSA-N
  }}

| Section2 = {{Chembox Properties
| Formula = C<sub>6</sub>H<sub>15</sub>N<sub>3</sub>S
| MolarMass = 161.2684 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
  }}

| Section3 = {{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
  }}
}}

'''Dimaprit''' is a [histamine](/source/histamine) analog working as a selective [H<sub>2</sub> histamine receptor](/source/Histamine_H2_receptor) [agonist](/source/agonist).<ref>{{cite book|editor1-last=Kartzung|editor1-first=Betram G.|editor2-last=Trevor|editor2-first=Anthony J.|title=Basic and Clinical Pharmacology|date=2014|publisher=McGraw-Hill Education|location=New York|isbn=978-0071825054|page=364|edition=13th}}</ref><ref>{{cite journal|last1=Kohno|first1=S|last2=Ogawa|first2=K|last3=Nabe|first3=T|last4=Yamamura|first4=H|last5=Ohata|first5=K|title=Dimaprit, a Histamine H<sub>2</sub>-agonist, Inhibits Anaphylactic Histamine Release from Mast Cells and the Decreased Release is Restored by Thioperamide (H<sub>3</sub>-antagonist), but not by Cimetidine (H<sub>2</sub>-antagonist)|journal=Japanese Journal of Pharmacology|date=May 1993|volume=62|issue=1|pages=75–9|pmid=7688057|doi=10.1254/jjp.62.75|doi-access=free}}<!--|access-date=7 January 2016--></ref><ref>{{cite journal|last1=Nakamura|first1=T|last2=Ueno|first2=Y|last3=Goda|first3=Y|last4=Nakamura|first4=A|last5=Shinjo|first5=K|last6=Nagahisa|first6=A|title=Efficacy of a Selective Histamine H<sub>2</sub> Receptor Agonist, Dimaprit, in Experimental Models of Endotoxin Shock and Hepatitis in Mice|journal=European Journal of Pharmacology|date=March 1997|volume=322|issue=1|pages=83–89|doi=10.1016/S0014-2999(96)00987-9|pmid=9088875}}<!--|access-date=7 January 2016--></ref>

==References==
{{reflist}}

{{Histaminergics}}

Category:Biogenic amines
Category:Amidines
Category:Thioethers
Category:Imidothiocarbamates
Category:Dimethylamino compounds
Category:Propylthio compounds

---
Adapted from the Wikipedia article [Dimaprit](https://en.wikipedia.org/wiki/Dimaprit) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Dimaprit?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.