# Cuffitis

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Cuffitis
> Markdown URL: https://mediated.wiki/source/Cuffitis.md
> Source: https://en.wikipedia.org/wiki/Cuffitis
> Source revision: 1321661730
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

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| caption         = Different regions of Ileal pouch-anal anastomosis
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| field           = [General surgery](/source/General_surgery)
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'''Cuffitis''' is inflammation at the anal transition zone or "cuff" created as a result of [ileal pouch-anal anastomosis](/source/Ileo-anal_pouch) (IPAA).<ref name=":0">{{Cite web|url=https://my.clevelandclinic.org/services/digestive_diseases/diseases-conditions/hic-pouchitis|title=Pouchitis: Causes, Symptoms & Treatment {{!}} Cleveland Clinic|website=my.clevelandclinic.org|access-date=2016-12-12}}</ref> It is considered a variant form of [ulcerative colitis](/source/ulcerative_colitis) that occurs in the rectal cuff.<ref name=":1">{{Cite journal|last=Shen|first=Bo|date=2016-12-12|title=Diagnosis and Management of Postoperative Ileal Pouch Disorders|journal=Clinics in Colon and Rectal Surgery|volume=23|issue=4|pages=259–268|doi=10.1055/s-0030-1268252|issn=1531-0043|pmc=3134805|pmid=22131896}}</ref> Cuffitis is a common complication of IPAA, particularly when a stapled [anastomosis](/source/Surgical_anastomosis) without [mucosectomy](/source/mucosectomy) procedure has been used.<ref name=":1" />

== Signs and symptoms ==
Symptoms of cuffitis mimic those of [pouchitis](/source/pouchitis).<ref name=":1" /> In addition, patients with cuffitis often present with small volume bloody bowel movements.<ref name=":1" /> Often, cuffitis can produce the appearance of bright red blood on tissue.<ref name=":0" />

=== Complications ===
Surgery-associated [ischemia](/source/ischemia) may contribute inflammation at the anal transitional zone.<ref name=":1" />

Patients whose cuffitis is refractory to mesalamine and/or corticosteroids should be evaluated for other disease in the cuff area, such as [fistula](/source/Anal_fistula) or anastomotic leaks.<ref name=":1" /> Cuffitis that is refractory to medication can also be a sign of [Crohn's disease](/source/Crohn's_disease) of the pouch.<ref name=":1" />

Chronic cuffitis can also contribute to the development of anastomotic [stricture](/source/Stricture_(medicine)).<ref name=":1" />

Cuffitis that is refractory, Crohn's-related, or is associated with surgical complications can contribute to pouch failure.<ref name=":1" />

== Diagnosis ==
Definitive diagnose of cuffitis is obtained by [endoscopy](/source/endoscopy).<ref name=":1" />

== Treatment ==
Cuffitis is treated with [mesalamine](/source/Mesalazine) suppositories or topical application of [lidocaine](/source/lidocaine) or [corticosteroid](/source/corticosteroid) medications.<ref name=":1" /> [Systemic medications](/source/Systemic_administration) are rarely used.<ref name=":1" />

== References ==
{{Reflist}}

Category:Gastrointestinal tract disorders
Category:Complications of surgical and medical care
Category:Inflammations

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Adapted from the Wikipedia article [Cuffitis](https://en.wikipedia.org/wiki/Cuffitis) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Cuffitis?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.