# Colorogenic

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{{one source |date=April 2024}}
'''Colorogenic''' or '''colourogenic''' describes a property of chemical compounds which are initially not [colored](/source/Color) (i.e. they show negligible [absorbance](/source/absorbance) of visible light), but become colored through a chemical reaction, often through an intermolecular covalent reaction that either covalently binds the now colored compound to a target molecule, or through a reaction which leads to a colored non-covalently bound product. Colorogenic reagents are often used for qualitative testing for the presence of chemical [functional groups](/source/functional_groups). Colorogenic labeling reagents are sometimes used in [analytical chemistry](/source/analytical_chemistry) procedures, for example in [HPLC](/source/High-performance_liquid_chromatography) or [CE](/source/capillary_electrophoresis) to derivative target compounds (e.g. labeling the [primary amines](/source/primary_amine) of [polypeptides](/source/polypeptides)), however the enhanced sensitivity from the analogous [fluorogenic](/source/fluorogenic) reagents, leads colorogenic reagents to be less frequently used in quantitative applications.<ref name="Fanali Haddad Poole Riekkola 2017 p. ">{{cite book | last=Fanali | first=Salvatore | last2=Haddad | first2=Paul R. | last3=Poole | first3=Colin | last4=Riekkola | first4=Marja-Liisa | title=Liquid chromatography. Volume 2, Applications | publication-place=Amsterdam, Netherlands | date=2017 | isbn=978-0-12-809344-3 | oclc=992119225 | language=en | page=}}</ref>

==Examples==
* [Ninhydrin](/source/Ninhydrin)
* [Ellman's reagent](/source/Ellman's_reagent)
* [PNPP](/source/para-Nitrophenylphosphate)

==See also==
* [Fluorogenic](/source/Fluorogenic)

==References==
{{reflist}}

Category:Analytical chemistry

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Adapted from the Wikipedia article [Colorogenic](https://en.wikipedia.org/wiki/Colorogenic) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Colorogenic?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.