# Cedrol

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Cedrol
> Markdown URL: https://mediated.wiki/source/Cedrol.md
> Source: https://en.wikipedia.org/wiki/Cedrol
> Source revision: 1305720139
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Chembox
| ImageFile = Cedrol skeletal.svg
| ImageSize = 
| ImageAlt = 
| IUPACName = 8α-Cedran-8β-ol
| SystematicName = (3''R'',3a''S'',6''R'',7''R'',8a''S'')-3,6,8,8-Tetramethyloctahydro-1''H''-3a,7-methanoazulen-6-ol
| OtherNames = 
|Section1={{Chembox Identifiers
| CASNo = 77-53-2
| CASNo_Ref = {{cascite|correct|CAS}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 63ZM9703BO
| PubChem = 65575
| ChemSpiderID = 59018
| ChEMBL = 1974890
| SMILES = O[C@@]2(CC[C@]31[C@@H](CC[C@H]1C)C([C@H]2C3)(C)C)C
| StdInChI = 1S/C15H26O/c1-10-5-6-11-13(2,3)12-9-15(10,11)8-7-14(12,4)16/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m1/s1
| StdInChIKey = SVURIXNDRWRAFU-OGMFBOKVSA-N
}}
|Section2={{Chembox Properties
| C=15 | H=26 | O=1
| Appearance =
| Density = 1.01 g/mL
| MeltingPtC = 86 to 87
| MeltingPt_ref = <ref>{{Merck12th|id=1961}}</ref>
| BoilingPtC = 273
| BoilingPt_ref = <ref>{{Aldrich|id=22135|name=(+)-Cedrol|accessdate=25 May 2011}}</ref>
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = 
 }}
}}
'''Cedrol''' is a [sesquiterpene](/source/sesquiterpene) [alcohol](/source/alcohol_(chemistry)) found in the [essential oil](/source/essential_oil) of [conifer](/source/conifer)s ([cedar oil](/source/cedar_oil)), especially in the genera ''[Cupressus](/source/Cupressus)'' (cypress) and ''[Juniperus](/source/Juniperus)'' (juniper). It has also been identified in ''[Origanum onites](/source/Origanum_onites)'', a plant related to [oregano](/source/oregano).<ref>{{cite book|editor=Connolly, JD |editor2=Hill, RA|title=Dictionary of Terpenoids |volume=1 Mono- and sesquiterpenoids|year=1991|publisher=Chapman&Hall|isbn=0-412-25770-X|at=SQ02555}}</ref> Its main uses are in the chemistry of [aroma compounds](/source/aroma_compounds).<ref>{{cite book|author=Breitmeier, E|title=Terpenes: flavors, fragrances, pharmaca, pheromones|year=2006|publisher=Wiley-VCH|isbn=3-527-31786-4|pages=46–47}}</ref> It makes up about 19% of cedarwood oil Texas and 15.8% of cedarwood oil Virginia.<ref>{{cite web|url=https://swiftcraftymonkey.blogspot.com/2012/02/essential-oils-cedarwood-science-of.html|title=Point of Interest!|author=Susan Barclay-Nichols|work=swiftcraftymonkey.blogspot.com}}</ref>

Cedrol has not been proven to be toxic in humans. It has been shown to have antioxidant and antiinflammatory along with other beneficial effects. In skin sensitization tests 2/20 people showed negative effects, and on the second test there was no sensitivity found. This compound and ones similar have been found to have antiseptic, anti-inflammatory, antispasmodic, tonic, astringent, diuretic, sedative, insecticidal, and antifungal activities ''[in vitro](/source/in_vitro)''.<ref>{{Cite journal |pmid = 25343299|year = 2014|last1 = Jeong|first1 = H. U.|last2 = Kwon|first2 = S. S.|last3 = Kong|first3 = T. Y.|last4 = Kim|first4 = J. H.|last5 = Lee|first5 = H. S.|title = Inhibitory effects of cedrol, β-cedrene, and thujopsene on cytochrome P450 enzyme activities in human liver microsomes|journal = Journal of Toxicology and Environmental Health. Part A|volume = 77|issue = 22–24|pages = 1522–32|doi = 10.1080/15287394.2014.955906}}</ref> These compounds are used globally in traditional medicine and cosmetics.<ref name="Cedrol toxicity">{{cite web  | url = https://www.nlm.nih.gov/toxnet/index.html | title = Cedrol | work = TOXNET: Toxicology Data Network}}</ref> Results of a 2015 study suggest that cedrol strongly attracts pregnant female mosquitoes after they have fed, which can be used to create cedrol-baited traps.<ref>{{cite journal | url=http://www.sciguru.org/newsitem/18734/cedrol-naturally-occurring-bait-malaria-spreading-pregnant-mosquitoes | title=Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex |author1=Lindh, Jenny |author2=Okal, Michael | journal=Malaria Journal |date=March 2015  | volume=14 | issue=119 | pages=119 | doi=10.1186/s12936-015-0636-0| pmid=25885703 | pmc=4404675 | doi-access=free }}</ref>

== See also ==
* [Cedrene](/source/Cedrene), another component of cedar oil

== References ==
{{reflist}}

Category:Sesquiterpenes

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Adapted from the Wikipedia article [Cedrol](https://en.wikipedia.org/wiki/Cedrol) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Cedrol?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.