# Cartwheel pattern

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Cartwheel pattern. This is a case of dermatofibrosarcoma protuberans from skin and soft tissue in the abdominal area. HE stain.

A **cartwheel pattern** is a [histopathologic architectural pattern](/source/Histopathologic_architecture). Microscopically, cartwheel arrangements appear to have center points that radiate cells or [connective tissue](/source/Connective_tissue) outward. Cartwheel patterns may be irregular and, at lower magnification, can cause tissue to appear tangled into clumps.[1]

[Skin tumors](/source/Skin_tumor) that can be classified as "storiform," having spindle cells with elongated nuclei radiating from a center point, are mainly:[2]

- [Fibrous histiocytoma](/source/Fibrous_histiocytoma) (dermatofibroma)

- Soft tissue [perineurioma](https://en.wikipedia.org/w/index.php?title=Perineurioma&action=edit&redlink=1)

- [Dermatofibrosarcoma protuberans](/source/Dermatofibrosarcoma_protuberans)

## References

1. **[^](#cite_ref-stone_1-0)** Stone, John H.; Zen, Yoh; Deshpande, Vikram (2012). "IgG4-Related Disease". *The New England Journal of Medicine*. **366**: 539–551. [doi](/source/Doi_(identifier)):[10.1056/NEJMra1104650](https://doi.org/10.1056%2FNEJMra1104650).

1. **[^](#cite_ref-ChoiRo2018_2-0)** Choi, Joon Hyuk; Ro, Jae Y. (2018). ["Cutaneous Spindle Cell Neoplasms: Pattern-Based Diagnostic Approach"](https://doi.org/10.5858%2Farpa.2018-0112-RA). *Archives of Pathology & Laboratory Medicine*. **142** (8): 958–972. [doi](/source/Doi_(identifier)):[10.5858/arpa.2018-0112-RA](https://doi.org/10.5858%2Farpa.2018-0112-RA). [ISSN](/source/ISSN_(identifier)) [0003-9985](https://search.worldcat.org/issn/0003-9985). [PMID](/source/PMID_(identifier)) [30040457](https://pubmed.ncbi.nlm.nih.gov/30040457).

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