# CUBRIC

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{{Short description|Brain imaging centre in Cardiff, Wales}}
{{For|the Serbian surname|Čubrić}}
{{Use dmy dates|date=December 2024}}
{{Infobox university
| name = Cardiff University Brain Research Imaging Centre
| native_name = 
| other_name = CUBRIC
| image = CUBRIC Building.png
| image_size = 250
| image_alt = The CUBRIC building at sunset
| caption = 
| motto = 
| motto_lang = 
| top_free_label = Cost of Construction
| top_free = £44,000,000 <ref name=CUBRIC>{{Cite web|title=Cardiff University Brain Research Imaging Centre (CUBRIC) {{!}} Cardiff University|url=https://www.cardiff.ac.uk/campus-developments/projects/cubric|access-date=2020-07-29|website=cardiff.ac.uk|language=en}}</ref>
| motto_eng = 
| former_names = 
| top_free_label1 = Architect
| top_free1 = [IBI Group](/source/IBI_Group)<ref name=CUBRIC/>
| top_free_label2 = Contractor
| top_free2 = [BAM Construction](/source/Royal_BAM_Group)<ref name=CUBRIC/>
| established = 2006
| closed = 
| type = Brain Imaging Centre
| parent = [Cardiff University](/source/Cardiff_University)
| affiliation = 
| address = Maindy Road, Cardiff
| city = [Cardiff](/source/Cardiff), [Wales](/source/Wales)
| postalcode = CF24 4HQ
| country = [United Kingdom](/source/United_Kingdom)
| coordinates = {{coord|51|29|34|N|3|11|4|W}}
| dean = 
| rector = 
| principal = 
| director = Prof. Derek Jones <ref name=CUBRIC/>
| head_label = 
| head = 
| academic_staff = <!-- or |faculty= -->
| students = <!-- or |enrollment= -->
| undergrad = 
| postgrad = 
| doctoral = 
| alumni = 
| symbol = 
| website = {{URL|https://www.cardiff.ac.uk/cardiff-university-brain-research-imaging-centre|CUBRIC - Cardiff University}}
| logo = 
| footnotes = 
| embedded = 
}}

The '''Cardiff University Brain Research Imaging Centre''' ('''CUBRIC''') is a brain imaging centre, part of [Cardiff University](/source/Cardiff_University)'s Science and Innovation Campus in [Cardiff](/source/Cardiff), [Wales](/source/Wales), United Kingdom.<ref name=IBI>{{cite web|url=http://www.ibigroup.com/2016/06/08/hrh-the-queen-opens-innovative-cubric-building/|title=Her Majesty The Queen Opens Innovative CUBRIC Building|date=8 June 2016|publisher=IBI Group|accessdate=24 July 2017}}</ref> When it expanded in 2016, it was considered the most advanced brain imaging centre in Europe.<ref name=BBC>{{cite web|url=https://www.bbc.com/news/uk-wales-32483208|title=Cardiff University's Cubric brain image centre milestone|date=30 April 2015|publisher=[BBC](/source/BBC)|work=BBC News Wales|accessdate=24 July 2017}}</ref><ref>{{Cite web|title=£44m brain imaging centre opens in Cardiff {{!}} Wellcome|url=https://wellcome.ac.uk/news/%C2%A344m-brain-imaging-centre-opens-cardiff|access-date=2020-07-29|website=wellcome.ac.uk}}</ref>

==Building==

=== Construction ===
CUBRIC was established in the [Cathays Park](/source/Cathays_Park) campus of Cardiff University in 2006, and moved to a new building in the Maindy Park campus in June 2016.<ref name=IBI/><ref name=Evans>{{cite web|url=http://www.walesonline.co.uk/news/wales-news/work-begins-cardiff-universitys-new-8010029|title=Work begins on Cardiff University's new £44m brain imaging centre|first=Gareth|last=Evans|date=28 October 2014|work=WalesOnline|publisher=Media Wales|accessdate=24 July 2017}}</ref><ref>{{cite web|url=http://www.cardiff.ac.uk/news/view/97663-major-milestone-for-new-44m-brain-imaging-centre|title=Major milestone for new £44m brain imaging centre|date=30 April 2015|publisher=Cardiff University|website=cardiff.ac.uk|accessdate=24 July 2017}}</ref> The new building was constructed on old railway land, with the railway aiding in the delivery of the larger scanners.<ref name=":0">{{Cite news|date=2016-06-07|title=Queen opens top brain imaging centre|language=en-GB|work=BBC News|url=https://www.bbc.com/news/uk-wales-south-east-wales-36444736|access-date=2020-07-29}}</ref><ref>{{Cite web|last=Psychology|first=Cardiff University|date=2 November 2015|title=CUBRIC 7 tesla Magnet Delivery, 31st October 2015|url=https://www.youtube.com/watch?v=eLaGIa9iERA|url-status=live|archive-url=https://web.archive.org/web/20190919002626/https://www.youtube.com/watch?v=eLaGIa9iERA |archive-date=2019-09-19 |access-date=29 July 2020|website=YouTube}}</ref> It cost £44,000,000, partially funded by Cardiff University, and partially by the [Welsh Government](/source/Welsh_Government).<ref name=":0" />  It was officially opened by [Queen Elizabeth II](/source/Elizabeth_II) on 7 June 2016.<ref name=":0" />

=== Awards ===
The new building was awarded the title of Life Science Research Building 2017 by the UK Science Park Association. It also received the "Project of the Year" and "Design Through Innovation" awards from the [Royal Institution of Chartered Surveyors](/source/Royal_Institution_of_Chartered_Surveyors),<ref>{{cite web|date=22 June 2017|title=Cardiff University Awarded for World Class Research Building|url=http://www.ibigroup.com/2017/06/22/ibi-group-and-cardiff-university-collect-awards-for-world-class-research-building/|accessdate=24 July 2017|publisher=IBI Group}}</ref> who praised it for its "precise and beautifully detailed multi-sensory design".<ref>{{Cite news|date=2017-04-28|title=Uni brain scan centre wins design award|language=en-GB|work=BBC News|url=https://www.bbc.com/news/uk-wales-39742821|access-date=2020-07-29}}</ref> It was also a contender for the [National Eisteddfod of Wales](/source/National_Eisteddfod_of_Wales) Gold Medal for Architecture in 2017.<ref>{{Cite web|last=Braidwood|first=Ella|title=Winner of Wales's best building announced|url=https://www.architectsjournal.co.uk/news/winner-of-waless-best-building-announced/10022284.article|access-date=2020-07-29|website=Architects Journal|language=en}}</ref> It has been designed to create a relaxing environment volunteers, with large windows and timber structures.<ref name=":0" /><ref>{{Cite web|title=Levolux gets the all clear in Cardiff|url=https://specificationonline.co.uk/articles/2016-08-04/levolux/levolux-gets-the-all-clear-in-cardiff-|access-date=2020-07-29|website=specificationonline.co.uk|language=en}}</ref>

==Research==

Cardiff University's School of Psychology created CUBRIC to facilitate interdisciplinary brain research, using multiple [neuroimaging](/source/neuroimaging) machines and laboratory techniques. The centre houses:

* 4 machines for [magnetic resonance imaging](/source/magnetic_resonance_imaging) (MRI)<ref name="IBI" /><ref name="Freeman" />
* [magnetoencephalography](/source/magnetoencephalography) (MEG)<ref name="Freeman" />
* [electroencephalography](/source/electroencephalography) (EEG) research<ref name="Freeman" />
* 5 [electrical brain stimulation](/source/electrical_brain_stimulation) (EBS) laboratories<ref name="IBI" />
* 10 cognitive method laboratories<ref name="IBI" />
* the first [connectome](/source/connectome) scanner outside the [United States](/source/United_States), a Siemens 3-tesla Connectom system.<ref name="BBC" /><ref>{{cite web|url=https://www.theguardian.com/higher-education-network/2017/mar/30/buildings-that-inspire-category-award-winner-and-runners-up|title=Buildings that inspire category: award winner and runners up|date=30 March 2017|accessdate=27 July 2017|work=The Guardian}}</ref>

A range of [cognitive neuroscience](/source/cognitive_neuroscience) studies are being carried out at CUBRIC, covering areas such as sleep research and curiosity research.<ref name="CardiffUniversity">{{cite web|url=https://www.cardiff.ac.uk/cardiff-university-brain-research-imaging-centre/research/themes/cognitive-neuroscience|title=Cognitive Neuroscience at CUBRIC|last=Cardiff University}}</ref> The centre aims to investigate neurological aspects of conditions such as [epilepsy](/source/epilepsy), [Alzheimer's disease](/source/Alzheimer's_disease), [schizophrenia](/source/schizophrenia),<ref name="Freeman">{{cite web|url=http://medicalphysicsweb.org/cws/article/opinion/51473|title=CUBRIC: a focus on brain research|date=13 November 2012|first=Tami|last=Freeman|website=medicalphysicsweb.org|publisher=IOP Publishing|accessdate=24 July 2017|archive-url=https://web.archive.org/web/20171229130424/http://medicalphysicsweb.org/cws/article/opinion/51473#|archive-date=2017-12-29|url-status=dead}}</ref><ref>{{Cite web|title=Advanced MRI scans could help predict people at risk of schizophrenia|url=https://medicalxpress.com/news/2015-05-advanced-mri-scans-people-schizophrenia.html|access-date=2020-07-29|website=medicalxpress.com|language=en}}</ref> [multiple sclerosis](/source/multiple_sclerosis), and [dementia](/source/dementia).<ref name="Evans" /> One of the centre's first major research projects in the new building involved the study of [Huntington's disease](/source/Huntington's_disease).<ref name="HD">{{cite news|url=http://sites.cardiff.ac.uk/cubric/cubric-enters-its-first-multi-center-phase-1-clinical-trial-for-treatment-of-huntingtons-disease/|title=CUBRIC enters its first multi-center Phase 1 Clinical Trial for treatment of Huntington’s Disease|date=18 May 2017|accessdate=26 July 2017|publisher=Cardiff University|website=sites.cardiff.ac.uk/cubric}}</ref>

The connectome scanner generates a map of the [axon](/source/axon)s in [white matter](/source/white_matter), connections of the brain, by measuring the nearby movement of water molecules to {{convert|1/1000|mm|in}} precision.<ref name=BBC/><ref>{{cite web|url=http://www.9news.com.au/world/2017/07/05/15/17/worlds-most-detailed-scan-of-the-human-brain-shows-how-information-travels|title=World's most detailed scan of the human brain shows how information travels|date=5 July 2017|accessdate=27 July 2017|publisher=Nine Digital|website=9news.com.au}}</ref><ref>{{cite web|url=http://www.news-medical.net/news/20160905/Neuroimaging-an-insight-into-psychiatric-causes-An-interview-with-Dr-Craig-Buckley.aspx|title=Neuroimaging: an insight into psychiatric causes? An interview with Dr Craig Buckley|first=April|last=Cashin-Garbutt|date=5 September 2016|accessdate=27 July 2017|publisher=AZO Network|website=News-medical.net}}</ref> Anomalous structures and changes to the brain's function, called [biomarker](/source/biomarker)s,<ref name=HD/> can be identified through comparison to scans of healthy brains.<ref name="Scott">{{cite AV media|url=https://www.youtube.com/watch?v=diPiSHxfGyE|people=Scott, Tom; Jones, Derek|date=24 July 2017|title=Connectome Scanning: Looking at the Brain's Wiring|medium=video|accessdate=24 July 2017|publisher=YouTube}}</ref><ref>{{Cite news|last=Walsh|first=Fergus|date=2017-07-03|title=What the brain's wiring looks like|language=en-GB|work=BBC News|url=https://www.bbc.com/news/health-40488545|access-date=2020-07-29}}</ref>

==References==
{{Reflist}}

==External links==
* {{Official|https://www.cardiff.ac.uk/cardiff-university-brain-research-imaging-centre}}
* [https://www.youtube.com/watch?v=xSeJjY9NGCc Tour of CUBRIC Building]
* [https://www.youtube.com/watch?v=diPiSHxfGyE Simple Explanation of Connectome Scanning]
* [https://www.youtube.com/watch?v=eLaGIa9iERA Delivery of 7T MRI Scanner]

{{Cardiff University}}

Category:Cardiff University
Category:Magnetoencephalography
Category:Medical imaging in the United Kingdom
Category:Medical imaging research institutes
Category:Medical research institutes in the United Kingdom
Category:Neuroimaging
Category:Neuroscience research centres in the United Kingdom

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Adapted from the Wikipedia article [CUBRIC](https://en.wikipedia.org/wiki/CUBRIC) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/CUBRIC?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.