# COMMD1
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{{Short description|Protein-coding gene in humans}}
{{Infobox_gene}}
'''COMM domain-containing protein 1''' is a [protein](/source/protein) that is encoded by the ''COMMD1'' [gene](/source/gene) in humans. It was originally regarded as Murr1 before being differentiated and renamed by Dr. Ezra Burstein's Lab[{{cite journal | vauthors = Nabetani A, Hatada I, Morisaki H, Oshimura M, Mukai T | title = Mouse U2af1-rs1 is a neomorphic imprinted gene | journal = Mol Cell Biol | volume = 17 | issue = 2 | pages = 789–98 |date=Feb 1997 | pmid = 9001233 | pmc = 231805 | doi = 10.1128/mcb.17.2.789}}][{{cite journal | vauthors = van De Sluis B, Rothuizen J, Pearson PL, van Oost BA, Wijmenga C | title = Identification of a new copper metabolism gene by positional cloning in a purebred dog population | journal = Hum Mol Genet | volume = 11 | issue = 2 | pages = 165–73 |date=Jan 2002 | pmid = 11809725 | doi =10.1093/hmg/11.2.165 | doi-access = free }}][{{cite web | title = Entrez Gene: COMMD1 copper metabolism (Murr1) domain containing 1| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=150684}}]
==References==
{{reflist}}
==External links==
* {{UCSC gene info|COMMD1}}
==Further reading==
{{refbegin | 2}}
*{{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}}
*{{cite journal | vauthors=Harrington JJ, Sherf B, Rundlett S |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 |s2cid=25064683 |display-authors=etal}}
*{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
*{{cite journal | vauthors=Müller T, van de Sluis B, Zhernakova A |title=The canine copper toxicosis gene MURR1 does not cause non-Wilsonian hepatic copper toxicosis. |journal=J. Hepatol. |volume=38 |issue= 2 |pages= 164–8 |year= 2003 |pmid= 12547404 |doi=10.1016/S0168-8278(02)00356-2 |display-authors=etal}}
*{{cite journal | vauthors=Tao TY, Liu F, Klomp L |title=The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein. |journal=J. Biol. Chem. |volume=278 |issue= 43 |pages= 41593–6 |year= 2004 |pmid= 12968035 |doi= 10.1074/jbc.C300391200 |display-authors=etal|doi-access=free }}
*{{cite journal | vauthors=Klomp AE, van de Sluis B, Klomp LW, Wijmenga C |title=The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis. |journal=J. Hepatol. |volume=39 |issue= 5 |pages= 703–9 |year= 2004 |pmid= 14568250 |doi=10.1016/S0168-8278(03)00380-5 }}
*{{cite journal | vauthors=Biasio W, Chang T, McIntosh CJ, McDonald FJ |title=Identification of Murr1 as a regulator of the human delta epithelial sodium channel. |journal=J. Biol. Chem. |volume=279 |issue= 7 |pages= 5429–34 |year= 2004 |pmid= 14645214 |doi= 10.1074/jbc.M311155200 |doi-access= free }}
*{{cite journal | vauthors=Ganesh L, Burstein E, Guha-Niyogi A |title=The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. |journal=Nature |volume=426 |issue= 6968 |pages= 853–7 |year= 2004 |pmid= 14685242 |doi= 10.1038/nature02171 |display-authors=etal|hdl=2027.42/62709 |s2cid=4344050 |hdl-access=free }}
*{{cite journal | vauthors=Burstein E, Ganesh L, Dick RD |title=A novel role for XIAP in copper homeostasis through regulation of MURR1. |journal=EMBO J. |volume=23 |issue= 1 |pages= 244–54 |year= 2004 |pmid= 14685266 |doi= 10.1038/sj.emboj.7600031 | pmc=1271669 |display-authors=etal}}
*{{cite journal | vauthors=Stuehler B, Reichert J, Stremmel W, Schaefer M |title=Analysis of the human homologue of the canine copper toxicosis gene MURR1 in Wilson disease patients. |journal=J. Mol. Med. |volume=82 |issue= 9 |pages= 629–34 |year= 2005 |pmid= 15205742 |doi= 10.1007/s00109-004-0557-9 |s2cid=8184776 }}
*{{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal | vauthors=Burstein E, Hoberg JE, Wilkinson AS |title=COMMD proteins, a novel family of structural and functional homologs of MURR1. |journal=J. Biol. Chem. |volume=280 |issue= 23 |pages= 22222–32 |year= 2005 |pmid= 15799966 |doi= 10.1074/jbc.M501928200 |display-authors=etal|doi-access=free }}
*{{cite journal | vauthors=Coronado VA, Bonneville JA, Nazer H |title=COMMD1 (MURR1) as a candidate in patients with copper storage disease of undefined etiology. |journal=Clin. Genet. |volume=68 |issue= 6 |pages= 548–51 |year= 2006 |pmid= 16283886 |doi= 10.1111/j.1399-0004.2005.00524.x |s2cid=27815621 |display-authors=etal}}
*{{cite journal | vauthors=Zhang Z, Joh K, Yatsuki H |title=Comparative analyses of genomic imprinting and CpG island-methylation in mouse Murr1 and human MURR1 loci revealed a putative imprinting control region in mice. |journal=Gene |volume=366 |issue= 1 |pages= 77–86 |year= 2006 |pmid= 16305817 |doi= 10.1016/j.gene.2005.08.020 |display-authors=etal}}
*{{cite journal | vauthors=de Bie P, van de Sluis B, Burstein E |title=Characterization of COMMD protein-protein interactions in NF-kappaB signalling. |journal=Biochem. J. |volume=398 |issue= 1 |pages= 63–71 |year= 2006 |pmid= 16573520 |doi= 10.1042/BJ20051664 | pmc=1525016 |display-authors=etal}}
*{{cite journal | vauthors=Sommerhalter M, Zhang Y, Rosenzweig AC |title=Solution structure of the COMMD1 N-terminal domain. |journal=J. Mol. Biol. |volume=365 |issue= 3 |pages= 715–21 |year= 2007 |pmid= 17097678 |doi= 10.1016/j.jmb.2006.10.030 | pmc=2706016 }}
*{{cite journal | vauthors=Maine GN, Mao X, Komarck CM, Burstein E |title=COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. |journal=EMBO J. |volume=26 |issue= 2 |pages= 436–47 |year= 2007 |pmid= 17183367 |doi= 10.1038/sj.emboj.7601489 | pmc=1783443 }}
{{refend}}
{{PDB Gallery|geneid=150684}}
{{gene-2-stub}}
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Adapted from the Wikipedia article [COMMD1](https://en.wikipedia.org/wiki/COMMD1) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/COMMD1?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.