# CNTNAP4

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> Source: https://en.wikipedia.org/wiki/CNTNAP4
> Source revision: 1300690367
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{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Contactin-associated protein-like 4''' is a [protein](/source/protein) that in humans is encoded by the ''CNTNAP4'' [gene](/source/gene).<ref name="pmid12093160">{{cite journal | vauthors = Spiegel I, Salomon D, Erne B, Schaeren-Wiemers N, Peles E | title = Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains | journal = Mol Cell Neurosci | volume = 20 | issue = 2 | pages = 283–97 |date=Jul 2002 | pmid = 12093160 | doi =10.1006/mcne.2002.1110  | s2cid = 25024421 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CNTNAP4 contactin associated protein-like 4| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=85445}}</ref>

This [gene product](/source/gene_product) belongs to the [neurexin](/source/neurexin) family, members of which function in the vertebrate [nervous system](/source/nervous_system) as [cell adhesion](/source/cell_adhesion) molecules and receptors. This protein, like other neurexin proteins, contains [epidermal growth factor](/source/epidermal_growth_factor) repeats and [laminin](/source/laminin) G domains. In addition, it includes an F5/8 type C domain, discoidin/[neuropilin](/source/neuropilin)- and [fibrinogen](/source/fibrinogen)-like domains, and thrombospondin N-terminal-like domains. [Alternative splicing](/source/Alternative_splicing) results in two transcript variants encoding different [isoforms](/source/isoforms).<ref name="entrez" />

==References==
{{reflist}}

==External links==
* {{UCSC gene info|CNTNAP4}}

==Further reading==
{{refbegin | 2}}
*{{cite journal  | vauthors=Kim JM, Lee KH, Jeon YJ |title=Identification of genes related to Parkinson's disease using expressed sequence tags |journal=DNA Res. |volume=13 |issue= 6 |pages= 275–86 |year= 2007 |pmid= 17213182 |doi= 10.1093/dnares/dsl016 |display-authors=etal|doi-access=free }}
*{{cite journal  | vauthors=Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406  | pmc=1356129 |display-authors=etal}}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
*{{cite journal  | vauthors=Nakayama M, Kikuno R, Ohara O |title=Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs |journal=Genome Res. |volume=12 |issue= 11 |pages= 1773–84 |year= 2003 |pmid= 12421765 |doi= 10.1101/gr.406902  | pmc=187542 }}
*{{cite journal  | vauthors=Nagase T, Kikuno R, Hattori A |title=Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=7 |issue= 6 |pages= 347–55 |year= 2001 |pmid= 11214970 |doi=10.1093/dnares/7.6.347  |display-authors=etal|doi-access=free }}
*{{cite journal  | vauthors=Auffray C, Behar G, Bois F |title=[IMAGE: molecular integration of the analysis of the human genome and its expression] |journal=Comptes Rendus de l'Académie des Sciences, Série III |volume=318 |issue= 2 |pages= 263–72 |year= 1995 |pmid= 7757816 |display-authors=etal}}
{{refend}}

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Adapted from the Wikipedia article [CNTNAP4](https://en.wikipedia.org/wiki/CNTNAP4) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/CNTNAP4?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.