# CLaCS
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{{Short description|Treatment for leg vein lesions}}
{{more citations needed|date=May 2014}}
'''CLaCS''' ('''Cryo-Laser and Cryo-Sclerotherapy''') is a treatment for leg vein lesions by combining transdermal [laser](/source/laser) effect and injection [sclerotherapy](/source/sclerotherapy), all under skin cooling (Cryo - cold air blown onto the skin at -20C).[{{Cite web |title=Cryo-laser and cryo-sclerotherapy guided by augmented reality for telangiectasias, feeder, and small varicose vein treatment–The CLaCS technique white paper report |url=https://scholar.google.com/citations?view_op=view_citation&hl=pt-BR&user=N96fCRUAAAAJ&citation_for_view=N96fCRUAAAAJ:BrmTIyaxlBUC |access-date=2024-07-10 |website=scholar.google.com}} ][{{Cite journal |last1=Miyake |first1=Roberto Kasuo |last2=Chi |first2=Yung-Wei |last3=Franklin |first3=Ian J. |last4=Gianesini |first4=Sergio |date= 2020|title=State of the art on cryo-laser cryo-sclerotherapy in lower limb venous aesthetic treatment |journal=Journal of Vascular Surgery. Venous and Lymphatic Disorders |volume=8 |issue=5 |pages=893–895 |doi=10.1016/j.jvsv.2020.01.003 |issn=2213-3348 |pmid=32179040|doi-access=free }}][{{Cite journal|last1=Miyake|first1=Hiroshi|last2=Miyake|first2=Kasuo|last3=Duarte|first3=Flávio|last4=Kikuchi|first4=Rodrigo|date=2008|title=Pequenas Varizes e Telangiectasias|trans-title=Small Varicose Veins and Telangiectasias|journal=Doenças Vasculares Periféricas|language=pt|edition=4|location=Rio de Janeiro, RJ|publisher=Guanabara Koogan S.A.|volume=2|pages=1769–1795|isbn=9788527714600}}] The laser causes a selective [photothermolysis](/source/Laser_hair_removal) damaging the vein wall. The vein's lumen gets smaller. On a second procedure, sclerosing agent is injected where the vein is still open. This combination can be used treat veins that could be treated by phleboectomy or foam [sclerotherapy](/source/sclerotherapy) - more invasive options. To improve results, CLaCS can be guided by [Augmented Reality](/source/Augmented_reality)[{{Cite news |title=Reality, only better, December 8th |url=https://www.economist.com/letters-to-the-editor-the-inbox/2007/12/19/reality-only-better-december-8th |access-date=2024-07-10 |newspaper=The Economist |issn=0013-0613}}
] ([near-infrared vein finder](/source/near-infrared_vein_finder)).[{{cite journal|title= Vein imaging: a new method of near infrared imaging, where a processed image is projected onto the skin for the enhancement of vein treatment|date=2014-01-24 |pmid=16918565 | doi=10.1111/j.1524-4725.2006.32226.x |volume=32 |issue=8 |journal=Dermatol Surg |pages=1031–8 | last1 = Miyake | first1 = RK | last2 = Zeman | first2 = HD | last3 = Duarte | first3 = FH | last4 = Kikuchi | first4 = R | last5 = Ramacciotti | first5 = E | last6 = Lovhoiden | first6 = G | last7 = Vrancken | first7 = C|s2cid=8872471 }}]
'''CLaCS''' was created by Dr. Roberto Kasuo Miyake (also knowns as Kasuo Miyake), in 1999, to adhere to patients' requests for treatment that did not require hospitalizations.