# Bulbus cordis

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Part of the developing heart

Bulbus cordis Heart showing expansion of the atria. Diagrams to illustrate the transformation of the bulbus cordis. Ao. Truncus arteriosus. Au. Atrium. B. Bulbus cordis. RV. Right ventricle. LV. Left ventricle. P. Pulmonary artery. Details Carnegie stage 9 Gives rise to smooth parts of right ventricle, left ventricle Identifiers Latin bulbus cordis Anatomical terminology [edit on Wikidata]

The **bulbus cordis** (the **bulb of the heart**) is a part of the [developing heart](/source/Heart_development) that lies ventral to the [primitive ventricle](/source/Primitive_ventricle) after the [heart](/source/Heart) assumes its S-shaped form. The superior end of the bulbus cordis is also called the **conotruncus**.[1]

## Structure

In the early [tubular heart](/source/Tubular_heart), the bulbus cordis is the major outflow pathway.[2] It receives blood from the [primitive ventricle](/source/Primitive_ventricle), and passes it to the [truncus arteriosus](/source/Truncus_arteriosus).[2][3] After [heart looping](/source/Heart_development), it is located slightly to the left of the ventricle.[3]

### Development

Further information: [Heart development](/source/Heart_development)

The early bulbus cordis is formed by the fifth week of [development](/source/Embryonic_development).[4] The truncus arteriosus is derived from it later.[2]

The adjacent walls of the bulbus cordis and ventricle approximate, fuse, and finally disappear, and the bulbus cordis now communicates freely with the [right ventricle](/source/Right_ventricle), while the junction of the bulbus with the [truncus arteriosus](/source/Truncus_arteriosus_(embryology)) is brought directly ventral to and applied to the [atrial canal](/source/Atrial_canal).

By the upgrowth of the [ventricular septum](/source/Ventricular_septum) the bulbus cordis is separated from the [left ventricle](/source/Left_ventricle), but remains an integral part of the right ventricle, of which it forms the [infundibulum](/source/Infundibulum_(heart)).

Together, the bulbus cordis and the primitive ventricle give rise to the [ventricles](/source/Ventricle_(heart)) of the formed heart.

## Other animals

The bulbus cordis is shared in the development of many animals, including [frogs](/source/Frog)[3] and [fish](/source/Fish).[5]

## Additional images

		- Head of chick embryo of about thirty-eight hours' incubation, viewed from the ventral surface. X 26

		- Diagram to illustrate the simple tubular condition of the heart.

		- Heart of human embryo of about fourteen days.

		- Human embryo about fifteen days old. Brain and heart represented from right side. Digestive tube and yolk sac in median section.

## References

*This article incorporates text in the [public domain](/source/Public_domain) from [page 513](https://archive.org/stream/anatomyofhumanbo1918gray#page/513/mode/2up) of the 20th edition of* [Gray's Anatomy](/source/Gray's_Anatomy) *(1918)*

1. **[^](#cite_ref-1)** Larsen, William J (2001). *Human Embryology* (3rd ed.). Elsevier. p. 160. [ISBN](/source/ISBN_(identifier)) [0-443-06583-7](https://en.wikipedia.org/wiki/Special:BookSources/0-443-06583-7).

1. ^ [***a***](#cite_ref-:0_2-0) [***b***](#cite_ref-:0_2-1) [***c***](#cite_ref-:0_2-2) Carlson, Bruce M. (2014), ["Development of the Heart"](http://www.sciencedirect.com/science/article/pii/B978012801238305460X), *Reference Module in Biomedical Sciences*, Elsevier, [ISBN](/source/ISBN_(identifier)) [978-0-12-801238-3](https://en.wikipedia.org/wiki/Special:BookSources/978-0-12-801238-3), retrieved 2021-01-05{{[citation](https://en.wikipedia.org/wiki/Template:Citation)}}: CS1 maint: work parameter with ISBN ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_work_parameter_with_ISBN))

1. ^ [***a***](#cite_ref-:1_3-0) [***b***](#cite_ref-:1_3-1) [***c***](#cite_ref-:1_3-2) De Iuliis, Gerardo; Pulerà, Dino (2011-01-01), De Iuliis, Gerardo; Pulerà, Dino (eds.), ["Chapter 6 – The Frog"](http://www.sciencedirect.com/science/article/pii/B9780123750600000061), *The Dissection of Vertebrates* (2nd ed.), Boston: Academic Press, pp. 127–145, [ISBN](/source/ISBN_(identifier)) [978-0-12-375060-0](https://en.wikipedia.org/wiki/Special:BookSources/978-0-12-375060-0), retrieved 2021-01-05{{[citation](https://en.wikipedia.org/wiki/Template:Citation)}}: CS1 maint: work parameter with ISBN ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_work_parameter_with_ISBN))

1. **[^](#cite_ref-4)** Belmont, John W. (2015), Moody, Sally A. (ed.), ["Chapter 33 – Genetic and Developmental Basis of Congenital Cardiovascular Malformations"](http://www.sciencedirect.com/science/article/pii/B9780124059450000338), *Principles of Developmental Genetics* (2nd ed.), Oxford: Academic Press, pp. 607–633, [ISBN](/source/ISBN_(identifier)) [978-0-12-405945-0](https://en.wikipedia.org/wiki/Special:BookSources/978-0-12-405945-0), retrieved 2021-01-05{{[citation](https://en.wikipedia.org/wiki/Template:Citation)}}: CS1 maint: work parameter with ISBN ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_work_parameter_with_ISBN))

1. **[^](#cite_ref-5)** Zaccone, G.; Marino, F.; Zaccone, D. (2011), ["Design and Physiology of the Heart | Intracardiac Neurons and Neurotransmitters in Fish"](http://www.sciencedirect.com/science/article/pii/B9780123745538002276), in Farrell, Anthony P. (ed.), *Encyclopedia of Fish Physiology*, San Diego: Academic Press, pp. 1067–1072, [ISBN](/source/ISBN_(identifier)) [978-0-08-092323-9](https://en.wikipedia.org/wiki/Special:BookSources/978-0-08-092323-9), retrieved 2021-01-05

## External links

- [Embryology at Temple](/source/Temple_University) *[Heart98/heart97b/sld023](https://web.archive.org/web/20120728034701/http://isc.temple.edu/marino/embryology/Heart98/heart97b/sld023.htm)*

- *[cardev-017](https://syllabus.med.unc.edu/courseware/embryo_images/unit-cardev/cardev_htms/cardev017.htm)*—Embryo Images at [University of North Carolina](/source/University_of_North_Carolina_at_Chapel_Hill)

- [MedEd at Loyola](/source/Loyola_University_Chicago) *[GrossAnatomy/thorax0/Heart_Development/AtrioVent.html](http://www.meddean.luc.edu/Lumen/MedEd/GrossAnatomy/thorax0/Heart_Development/AtrioVent.html)*

- Kirby, Margaret L. (2007). [*Cardiac development*](https://books.google.com/books?id=fjhCQ-QbtbsC). [Oxford University Press](/source/Oxford_University_Press). p. 119. [ISBN](/source/ISBN_(identifier)) [978-0-19-517819-7](https://en.wikipedia.org/wiki/Special:BookSources/978-0-19-517819-7). Retrieved 20 April 2011.

v t e Development of the circulatory system Heart Tubular heart Truncus arteriosus Bulbus cordis Primitive ventricle Primitive atrium Sinus venosus Chamber formation Atrioventricular Primary interventricular foramen Endocardial cushions Septum intermedium Atrioventricular canal Atrial Septum primum Foramen secundum Primary interatrial foramen Septum secundum Foramen ovale Other Aorticopulmonary septum Protein signalling in heart development Vessels Arteries Dorsal aorta Aortic arches Aortic sac Veins Anterior cardinal vein Posterior cardinal vein Common cardinal veins Lymph vessels Lymph sacs Other Vascular remodelling in the embryo Extraembryonic hemangiogenesis Blood islands Chorion Connecting stalk Yolk sac Placenta Fetal circulation umbilical cord: Umbilical vein → Ductus venosus → Inferior vena cava → Heart → Pulmonary artery → Ductus arteriosus → Aorta → Umbilical artery yolk sac: Vitelline veins Vitelline arteries

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Adapted from the Wikipedia article [Bulbus cordis](https://en.wikipedia.org/wiki/Bulbus_cordis) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Bulbus_cordis?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.