# Brandon Colby

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{{short description|American physician}}

{{Multiple issues|
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'''Brandon Ross Colby''' is an American physician in [Beverly Hills, California](/source/Beverly_Hills%2C_California)<ref name=DCA>{{cite web |url=https://search.dca.ca.gov/details/8002/A/92750/105fd2e896b553d2d2ccf357bb58da23 |title=Licensing details for: A 92750 |last= |first= |date= |website=California Department of Consumer Affairs |publisher= |access-date=July 16, 2024 |quote=}}</ref> and [physician](/source/physician) specializing in [predictive medicine](/source/predictive_medicine) and [genetic testing](/source/genetic_testing). He is [author](/source/author) of ''Outsmart Your Genes'', a book about genetics published in 2011, and he is the founder and CEO of [direct-to-consumer genetic testing](/source/direct-to-consumer_genetic_testing) service Sequencing.<ref>{{cite web | last=Rabbitt | first=Meghan | title=Tips to Outsmart Genetic Health Risks | website=Prevention | date=February 24, 2021 | url=https://www.prevention.com/health/a35369807/genetics-and-health/ | access-date=July 17, 2024}}</ref>

== Early life and education ==
Colby was born with [epidermolysis bullosa simplex](/source/epidermolysis_bullosa_simplex) (EB), a rare [genetic disease](/source/genetic_disease) that causes heat-sensitivity of the skin, leading to blisters on the hands and feet when skin temperature rises. Because of his condition he had an interest in genetics early in life.<!--<ref name=Annuity>{{cite web|url=http://www.annuitydigest.com/blog/tom/doctor-brandon-colby-predictive-medicine-power-prevention-and-planning-long-retirement |title=Interview with Brandon Colby |publisher=Annuitydigest.com |date= |access-date=2011-06-01}}</ref>-->

Colby holds a degree in genetics from the [University of Michigan](/source/University_of_Michigan), a 2004 [Medical Doctorate](/source/Doctor_of_Medicine) from [Mount Sinai School of Medicine](/source/Mount_Sinai_School_of_Medicine),<ref name=DCA/> and a 2007 [Master of Business Administration](/source/Master_of_Business_Administration) from [Stanford University's Graduate School of Business](/source/Stanford_University_Graduate_School_of_Business).<ref name="Stanford">{{cite web |author-first=Dana |author-last=Mauriello | title=Brandon Colby, MBA '07: Charting the Course for a Predictive Medicine Venture | website=Stanford Graduate School of Business | date=November 2, 2017 | url=https://www.gsb.stanford.edu/experience/news-history/brandon-colby-mba-07-charting-course-predictive-medicine-venture | access-date=July 17, 2024}}</ref><ref>{{Cite web |title=Outsmart Your Genes {{!}} Dr. Brandon Colby MD |url=https://sequencing.com/education-center/outsmart-your-genes |access-date=2023-02-26 |website=Sequencing.com |language=en}}</ref><!--<ref>Staff, Eternity Medicine.[http://www.eternitymedicine.com/index.php/doctors/doctor_detail/62 Dr. Brandon Colby at Eternity Medicine] {{webarchive |url=https://web.archive.org/web/20130629183710/http://www.eternitymedicine.com/index.php/doctors/doctor_detail/62 |date=June 29, 2013 }}</ref>-->

== Career ==

Colby founded [Existence Genetics](/source/Existence_Genetics) in 2005 during his second year at Stanford.<ref name="Stanford"/> The business declared [bankruptcy](/source/Chapter_7%2C_Title_11%2C_United_States_Code) on November 21, 2012.<!--<ref>Staff, business-bankruptcies.com. [http://business-bankruptcies.com/cases/existence-genetics-llc Existence Genetics, LLC bankruptcy information] Accessed June 3, 2013</ref>--> Existence Genetics was a genetic analysis and genetic reporting company that provided the healthcare industry and health & wellness organizations with information about their clients' genes.<ref>{{cite web|author=Steve Parker |url=http://www.genomeweb.com/dxpgx/existence-genetics-ramps-widespread-test-service-launch-eyes-whole-genome-sequen |title=Existence Genetics Ramps up for Widespread Test Service Launch, Eyes Whole-Genome Sequencing |publisher=GenomeWeb |date= 8 October 2010|access-date=2011-06-01}}</ref>

Colby was also medical director of Existence Health, a medical practice founded in 2010 and based in Los Angeles that provided [predictive medicine](/source/predictive_medicine) services to its patients based upon a person's genes.<!--<ref name=Annuity/>-->

=== Sequencing ===

Colby founded Sequencing (sequencing.com), which launched in September 2016. It hosts genomic sequencing data for individuals and for researchers, an [API](/source/Application_programming_interface) through which third parties can interface with the data, and an [app store](/source/app_store). The app store allows purchase of further genetic data interpretation, such as results for [Alzheimer's disease](/source/Alzheimer's_disease).<ref>{{cite web | last=Richards| first=Sarah Elizabeth| title=Now You Can Genetically Test Your Child For Disease Risks. Should You? | website=Smithsonian Magazine | date=February 5, 2018 | url=https://www.smithsonianmag.com/science-nature/now-you-can-genetically-test-your-child-should-you-180968012/ | access-date=July 17, 2024}}</ref> Genomics Personalized Health provides genomic sequencing, EncrypGen provides secure data transfer with [blockchain](/source/blockchain), and Sequencing hosts genomic data and offers interpretation of results.<ref>    {{cite web |url=https://news.marketersmedia.com/encrypgen-inc-add-new-alliances-sequencing-com-genomics-personalized-health/293670 |title=EncrypGen, Inc. Add New Alliances: Sequencing.com & Genomics Personalized Health |last= |first= |date=January 29, 2018 |website=Marketers Media |publisher= |access-date=July 18, 2024 |type=Press release}}</ref><ref>DNA Can Guide the Way: Genome Mapping Offers Look Into Medical Future. ''Corpus Christi Caller - Times'', July 07, 2016. https://www.proquest.com/newspapers/dna-can-guide-way/docview/2581329790/se-2 (accessed July 19, 2024).</ref><ref>{{cite web | title=Sequencing.com launches genetic data platform | website=ProQuest | url=https://www.proquest.com/docview/1847407330 | ref={{sfnref | ProQuest}} | access-date=2024-07-19| id={{ProQuest|1847407330}} }}</ref> A [patent](/source/patent) assigned to sequencing.com was filed in 2014.<ref>{{cite web |url=https://go.gale.com/ps/retrieve.do?tabID=T002&resultListType=RESULT_LIST&searchResultsType=SingleTab&retrievalId=60a35c59-c25a-466b-ad73-5bb90ecea9e5&hitCount=5&searchType=AdvancedSearchForm&currentPosition=4&docId=GALE%7CA470796058&docType=Article&sort=Relevance&contentSegment=ZONE-Exclude-FT&prodId=AONE&pageNum=1&contentSet=GALE%7CA470796058&searchId=R4&userGroupName=wikipedia&inPS=true |title=Researchers Submit Patent Application, "System and Method for Real-Time Personalization Utilizing an Individual'S Genomic Data", for Approval (USPTO 20160321395) |last= |first= |date=November 26, 2016 |website=Gale Academic OneFile |publisher=NewsRX |access-date=July 18, 2024 |quote=}}</ref><ref>{{cite journal | last1=Guerrini | first1=Christi J. | last2=Lewellyn | first2=Meaganne | last3=Majumder | first3=Mary A. | last4=Trejo | first4=Meredith | last5=Canfield | first5=Isabel | last6=McGuire | first6=Amy L. | title=Donors, authors, and owners: how is genomic citizen science addressing interests in research outputs? | journal=BMC Medical Ethics | volume=20 | issue=1 | date=2019 | page=84 | issn=1472-6939 | pmid=31752834 | pmc=6868686 | doi=10.1186/s12910-019-0419-1 | doi-access=free}}</ref>

In 2022, Sequencing raised five million dollars in a round of [venture capital financing](/source/venture_capital_financing).<ref>{{cite web |url=https://vcnewsdaily.com/sequencing.com/venture-capital-funding/scdxdlnzns |title=Sequencing.com Raises $5M In Venture Capital |last= |first= |date=November 9, 2022 |website=VC News Daily |publisher=Massinvestor |access-date=July 18, 2024 |quote=}}</ref><ref>"VC Health Pulse: Expected Gridlock in Washington Shifts Healthcare VCs' Attention to States; Biotech Startup Juvena Therapeutics Grabs $41 Million." Dow Jones Institutional News, November 10, 2022, https://www.proquest.com/wire-feeds/vc-health-pulse-expected-gridlock-washington/docview/2734893339/se-2 (accessed July 19, 2024).</ref> Sequencing has been profiled as a "key company" in ResearchandMarkets.com's [whole genome](/source/Whole_genome_sequencing) and exome [market research](/source/market_research) reports since 2021.<ref>{{cite web |url=https://www.prnewswire.com/news-releases/whole-genome-and-exome-sequencing-market-analysis-2023-2024-and-2027-with-executive-and-consultant-guides-featuring-llumina-ion-pacific-biosystems-roche-solid-oxford-nanopore-among-others-302101528.html |title=Whole Genome and Exome Sequencing Market Analysis 2023-2024 and 2027 with Executive and Consultant Guides Featuring llumina, ION, Pacific Biosystems, Roche, SOLiD, Oxford Nanopore Among Others  |last= |first= |date=March 28, 2024 |website=PR Newswire |publisher= |access-date=July 18, 2024 |type=Press release}}</ref><ref>{{cite web |url=https://www.businesswire.com/news/home/20211005005851/en/Whole-Genome-And-Exome-Sequencing-Markets-Q4-2021-Market-Report---ResearchAndMarkets.com |title=Whole Genome And Exome Sequencing Markets, Q4 2021 Market Report - ResearchAndMarkets.com |last= |first= |date=October 5, 2021 |website=Business Wire |publisher= |access-date=July 18, 2024 |type=Press release}}</ref>

== Publications ==

Colby co-authored "Congenital erythropoietic porphyria: identification and expression of eight novel mutations in the uroporphyrinogen III synthase gene", which appeared in [British Journal of Haematology](/source/British_Journal_of_Haematology) in 2002. In 2010, [Penguin Random House](/source/Penguin_Random_House) published Colby's ''Outsmart Your Genes'' ({{ISBN|9780399536380}}), a book about genetic testing and predictive medicine.<ref>{{cite journal | last1=Shady | first1=Amr A. | last2=Colby | first2=Brandon R. | last3=Cunha | first3=Luis F. | last4=Astrin | first4=Kenneth H. | last5=Bishop | first5=David F. | last6=Desnick | first6=Robert J. | title=Congenital erythropoietic porphyria: identification and expression of eight novel mutations in the uroporphyrinogen III synthase gene | journal=British Journal of Haematology | volume=117 | issue=4 | date=2002 | issn=0007-1048 | doi=10.1046/j.1365-2141.2002.03558.x | pages=980–987| pmid=12060141 }}</ref><ref>Brendan Colby. Outsmart Your Genes: How Understanding Your DNA Will Empower You to Protect Yourself Against Cancer, Alzheimer's, Heart Disease, Obesity, and Many Other Conditions. Penguin, 2010. {{ISBN|0399535578}}</ref><ref>Andrea Hoffmann and Panagiotis A Tsonis. [http://www.humgenomics.com/content/5/5/516 Book Review: Outsmart Your Genes] Human Genomics 2011, 5:516-517</ref>

== Media appearances ==

In April 2011, Colby appeared on the "How to Outsmart Your Genes" episode of the TV show ''[The Doctors](/source/The_Doctors_(2008_TV_series))''. Existence Genetics performed genetic testing on several of the show's guests and Colby discussed the results. The testing focused on male pattern baldness, sexual compatibility, preconception, and disease predisposition.<ref>{{cite web |url=http://www.thedoctorstv.com/main/show_synopsis/741?section=synopsis |archive-url=https://web.archive.org/web/20110426061944/http://www.thedoctorstv.com/main/show_synopsis/741?section=synopsis |url-status=dead |archive-date=2011-04-26 |title=Show Synopsis |publisher=Thedoctorstv.com |date= |access-date=2011-06-01 }}</ref>

Colby has also appeared on ABC's ''Good Morning America'' in April, 2010, and the [Today Show](/source/Today_(American_TV_program)) with [Megyn Kelly](/source/Megyn_Kelly) in 2018.<!--<ref>{{cite web|author=04/14/2010 |url=https://abcnews.go.com/Health/video/outsmart-genes-10375764 |title=Outsmart Your Genes |work=ABC News |date=2010-04-14 |access-date=2011-06-01 |url-status=dead}}</ref>--><ref>Kelly, Megyn. A look at the story of Taylor Muhl. Today (Feb 23, 2018), https://www.proquest.com/other-sources/look-at-story-taylor-muhl/docview/2008176519/se-2 (accessed July 19, 2024).</ref>

== See also ==

* [Anne Wojcicki](/source/Anne_Wojcicki)
* [Helix (genomics company)](/source/Helix_(genomics_company))
* [Gilad Japhet](/source/Gilad_Japhet)

== References ==

{{Reflist}}

== Further reading ==

* {{cite news|last1=Ashford|first1=Molika|title=Sequencing.com Hopes to Shepherd Growing Market of DIY Genomics Tools|url=https://www.genomeweb.com/sequencing/sequencingcom-hopes-shepherd-growing-market-diy-genomics-tools|date=27 September 2016}}
* {{cite web |url=https://www.the-scientist.com/what-your-dna-cant-tell-you-66523 |title=What Your DNA Can't Tell You |last=Kwon |first=Diana |date=October 2, 2019 |website=[The Scientist](/source/The_Scientist_(magazine)) |publisher=LabX Media Group |access-date= |quote= |url-access=registration}}
*  {{cite web |url=https://www.healthcare-brew.com/stories/2023/07/24/direct-to-consumer-genome-sequencing-could-be-key-to-the-future-of-healthcare |title=Direct-to-consumer genome sequencing could be key to the future of healthcare |last=Young |first=Shannon |date=July 24, 2023 |website=Healthcare Brew |publisher=Morning Brew, Inc |access-date= |quote=}}

== External links ==

* [https://sequencing.com/ Sequencing.com]
* [https://www.outsmartyourgenes.com/index.php Outsmart Your Genes official website]
* [https://www.penguinrandomhouse.com/books/304995/outsmart-your-genes-by-brandon-colby/ Outsmart Your Genes] at [Penguin Random House](/source/Penguin_Random_House)
* Preview {{Google books|id=CP6IH8CmO6kC|title=Outsmart Your Genes: How Understanding Your DNA Will Empower You to Protect Yourself Against Cancer, Alzheimer's, Heart Disease, Obesity, and Many Other Conditions}}
* Preview [https://archive.org/details/outsmartyourgene0000colb_x0h0 ''Outsmart Your Genes''] at [Internet Archive](/source/Internet_Archive)

{{authority control}}

{{DEFAULTSORT:Colby, Brandon}}
Category:American chief executives in the health care industry
Category:American geneticists
Category:American businesspeople in the pharmaceutical industry
Category:American businesspeople in the health care industry
Category:American medical writers
Category:American male non-fiction writers
Category:American medical researchers
Category:University of Michigan alumni
Category:Living people
Category:Year of birth missing (living people)
Category:Stanford Graduate School of Business alumni
Category:Icahn School of Medicine at Mount Sinai alumni

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Adapted from the Wikipedia article [Brandon Colby](https://en.wikipedia.org/wiki/Brandon_Colby) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Brandon_Colby?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.