# Amphid

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{{short description|Structure in nematode anatomy}}
{{one source|date=March 2026}}
'''Amphids''' ([Greek](/source/Greek_language): ''amphi'', around, double) are innervated invaginations of [cuticle](/source/cuticle) in [nematode](/source/nematode)s. They are usually found in the anterior (head) region of the animal, at the base of the lips. Amphids are the principal [olfactosensory](/source/Sense_of_smell) organs of nematodes. Each amphid in ''[C. elegans](/source/C._elegans)'' is made up of 12 [sensory neuron](/source/sensory_neuron)s  with ciliated [dendrite](/source/dendrite)s.<ref name="o094">{{cite journal | last1=Ekino | first1=Taisuke | last2=Shinya | first2=Ryoji | title=Ultrastructural Description of Amphid Neurons in the Pine Wood Nematode Indicates Concurrent Evolution of the Stylet and Specific Neurons | journal=Journal of Comparative Neurology | volume=533 | issue=11 | date=2025 | issn=0021-9967 | pmid=41221698 | pmc=12606542 | doi=10.1002/cne.70114 | url=https://onlinelibrary.wiley.com/doi/10.1002/cne.70114 | access-date=2026-03-01 | page=}}</ref> The neurons have multiple shapes, such as single cilium, double cilia, wing-like cilia, and dendrites embedded in the sheath-cell with villa.<ref name="o094"/> Other nematodes, such as ''[Bursaphelenchus xylophilus](/source/Bursaphelenchus_xylophilus)'', have different configurations of specific types of neurons, with ''B. xylophilus''’ amphids having 13 neurons rather than 12.<ref name="o094"/>

== References ==
{{Reflist}}

Category:Nematode anatomy
Category:Invertebrate nervous system

{{nematode-stub}}

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Adapted from the Wikipedia article [Amphid](https://en.wikipedia.org/wiki/Amphid) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Amphid?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.
