# Alphanodavirus

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***Alphanodavirus*** is a genus of non-enveloped [positive-strand RNA viruses](/source/Positive-strand_RNA_virus) in the family *[Nodaviridae](/source/Nodaviridae)*.[1] Insects, mammals, and fishes serve as natural hosts. Diseases associated with this genus include: Nodamura virus paralysis in infected wax moth larvae. Member viruses can also provoke paralysis and death to suckling mice and suckling hamsters. There are five species in this genus.[2][3]

## Structure

Viruses in the genus *Alphanodavirus* are [non-enveloped](/source/Viral_envelope), with icosahedral geometries, and T=3 symmetry. The diameter is around 30 nm. Genomes are linear and segmented, bipartite, around 21.4kb in length.[2][3]

## Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the [positive-strand RNA virus](/source/Positive-strand_RNA_virus) replication model. Positive-strand RNA virus transcription, using the internal initiation model of subgenomic RNA transcription is the method of transcription. Member viruses are released by [lysis](/source/Lysis) of the infected host cell. Insects, mammals, and fishes serve as the natural host.[2][3]

## Taxonomy

The genus contains the following species, listed by scientific name and followed by their common names:[4]

- *Alphanodavirus boolarraense*, [Boolarra virus](/source/Boolarra_virus)
- *Alphanodavirus flockense*, [Flock House virus](/source/Flock_House_virus)
- *Alphanodavirus heteronychi*, [Black beetle virus](/source/Black_beetle_virus)
- *Alphanodavirus nodamuraense*, [Nodamura virus](/source/Nodamura_virus)
- *Alphanodavirus pariacotoense*, [Pariacoto virus](/source/Pariacoto_virus)

## References

1. Sahul Hameed, AS; Ninawe, AS; Nakai, T; Chi, SC; Johnson, KL; ICTV Report, Consortium (January 2019). "ICTV Virus Taxonomy Profile: Nodaviridae.". *The Journal of General Virology*. **100** (1): 3–4. [doi:10.1099/jgv.0.001170](https://doi.org/10.1099/jgv.0.001170). [PMC 12662032](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12662032). [PMID 30431412](https://pubmed.ncbi.nlm.nih.gov/30431412)

1. ["ICTV Report Nodaviridae"](http://www.ictv.global/report/nodaviridae)

1. ["Viral Zone"](http://viralzone.expasy.org/all_by_species/611.html). ExPASy. Retrieved 12 June 2015.

1. ["Virus Taxonomy: 2024 Release"](https://ictv.global/taxonomy). International Committee on Taxonomy of Viruses. Retrieved 12 March 2025.

## External links

- [**ICTV Report:** *Nodaviridae*](http://www.ictv.global/report/nodaviridae)
- [**Viralzone**: Alphanodavirus](http://viralzone.expasy.org/all_by_species/611.html)

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Adapted from the Wikipedia article [Alphanodavirus](https://en.wikipedia.org/wiki/Alphanodavirus) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Alphanodavirus?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.