# Alcohol intoxication

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Behavioural and physical changes due to the consumption of alcohol

"Drunk" redirects here. For other uses, see [Drunk (disambiguation)](/source/Drunk_(disambiguation)).

"Buzzed" redirects here. For the TV episode, see [Buzzed (Entourage)](/source/Buzzed_(Entourage)).

Medical condition

Alcohol intoxication Other names Inebriation, drunkenness, ethanol intoxication, internal damage by alcohol[1][2] The Drunkenness of Noah by Michelangelo, 1509 Specialty Toxicology, psychiatry Symptoms Mild: Mild sedation, decreased coordination[3] Moderate: Slurred speech, trouble walking, vomiting[3] Severe: Decreased effort to breathe, coma[3] Complications Seizures, aspiration pneumonia, injuries, low blood sugar[3][4] Usual onset Over minutes to hours (depends on how much one drinks)[5] Duration Several hours[5] Causes Alcohol (ethanol)[6] Risk factors Social environment, impulsivity, anxiety, alcoholism[5][7] Diagnostic method Typically based on history of events and physical examination[6] Differential diagnosis Hepatic encephalopathy, Wernicke encephalopathy, methanol toxicity, meningitis, traumatic brain injury[6] Treatment Supportive care[6] Frequency Very common Deaths c. 2,200 per year (U.S.)[8]

**Alcohol intoxication**, commonly described in higher doses as **drunkenness** or **inebriation**,[9] and known in [overdose](/source/Overdose) as **alcohol poisoning**,[1] is the behavior and physical effects caused by recent consumption of [alcohol](/source/Alcohol_(drug)).[6][10] The technical term *intoxication* in common speech may suggest that a large amount of alcohol has been consumed, leading to accompanying physical symptoms and deleterious health effects. Mild intoxication is mostly referred to by slang terms such as *tipsy* or *buzzed*. In addition to the [toxicity](/source/Toxicity) of [ethanol](/source/Ethanol), the main [psychoactive](/source/Psychoactive_drug) component of alcoholic beverages, other physiological symptoms may arise from the activity of [acetaldehyde](/source/Acetaldehyde), a [metabolite](/source/Metabolite) of alcohol.[11] These effects may not arise until hours after ingestion and may contribute to a condition colloquially known as a [hangover](/source/Hangover).

Symptoms of [intoxication](/source/Substance_intoxication) at lower doses may include mild [sedation](/source/Sedation) and poor coordination.[3] At higher doses, there may be slurred speech, [trouble walking](/source/Ataxia#Exogenous_substances_(metabolic_ataxia)), impaired vision, mood swings and vomiting.[3] Extreme doses may result in a [respiratory depression](/source/Hypoventilation), coma, or death.[3] Complications may include [seizures](/source/Seizures), [aspiration pneumonia](/source/Aspiration_pneumonia), [low blood sugar](/source/Hypoglycemia), and injuries or self-harm such as [suicide](/source/Suicide).[3][4] Alcohol intoxication can lead to [alcohol-related crime](/source/Alcohol-related_crime), with perpetrators more likely to be intoxicated than victims.[12]

Alcohol intoxication typically begins after two or more [alcoholic drinks](/source/Alcoholic_drink).[5] Alcohol has the potential for abuse. Risk factors include a social situation where heavy drinking is common and a person having an impulsive personality.[5] Diagnosis is usually based on the history of events and physical examination.[6] Verification of events by witnesses may be useful.[6] Legally, alcohol intoxication is often defined as a [blood alcohol concentration](/source/Blood_alcohol_concentration) (BAC) of greater than 5.4–17.4 mmol/L (25–80 mg/dL or 0.025–0.080%).[13][14] This can be measured by blood or [breath testing](/source/Breathalyzer).[5] Alcohol is broken down in the human body at a rate of about 3.3 mmol/L (15 mg/dL) per hour,[6] depending on an individual's [metabolic rate](/source/Metabolic_rate) ([metabolism](/source/Metabolism)).[15] The [DSM-5](/source/DSM-5) defines alcohol intoxication as at least one of the following symptoms that developed during or close after alcohol ingestion: slurred speech, incoordination, unsteady walking/movement, nystagmus (uncontrolled eye movement), attention or memory impairment, or near unconsciousness or coma.[16]

Management of alcohol intoxication involves supportive care.[6] Typically, this includes putting the person in the recovery position, keeping the person warm, and making sure breathing is sufficient.[4] [Gastric lavage](/source/Gastric_lavage) and [activated charcoal](/source/Activated_charcoal) have not been found to be useful.[6] Repeated assessments may be required to rule out other potential causes of a person's symptoms.[6]

Acute intoxication has been documented throughout history, and alcohol remains one of the world's most widespread [recreational drugs](/source/Recreational_drug).[17][18] Some religions, such as Islam, consider alcohol intoxication to be a sin.[5][19]

## Symptoms

See also: [Short-term effects of alcohol consumption](/source/Short-term_effects_of_alcohol_consumption)

- [Vomiting](/source/Vomiting)[10]

- [Slow breathing](/source/Bradypnea) (fewer than eight breaths per minute)[12]

- [Seizures](/source/Seizure)[14]

- [Blue, grey or pale skin](/source/Pallor)[15]

- [Hypothermia](/source/Hypothermia) (Low body temperature)[16]

- [Lethargy](/source/Lethargy) (Trouble staying conscious)[17]

*Wine is a Mocker* by [Jan Steen](/source/Jan_Steen) c. 1663

Alcohol intoxication leads to negative health effects due to the recent drinking of large amount of [ethanol](/source/Ethanol) (alcohol).[6][20] When severe it may become a [medical emergency](/source/Medical_emergency). Some effects of alcohol intoxication, such as euphoria and lowered [social inhibition](/source/Social_inhibition), are central to alcohol's desirability.[21]

As drinking increases, people become sleepy or fall into a [stupor](/source/Stupor). At very high [blood alcohol concentrations](/source/Blood_alcohol_concentration), for example, above 0.3%, the respiratory system becomes depressed and the person may stop breathing.[22] Comatose patients may aspirate their vomit (resulting in vomitus in the lungs, which may cause "drowning" and later [pneumonia](/source/Pneumonia) if survived). CNS depression and impaired motor coordination, along with poor judgment, increase the likelihood of accidental injury occurring. It is estimated that about one-third of alcohol-related deaths are due to accidents, and another 14% are from intentional injury.[23]

In addition to respiratory failure and accidents caused by its effects on the central nervous system, alcohol causes significant metabolic derangements. [Hypoglycaemia](/source/Hypoglycaemia) occurs due to ethanol's inhibition of [gluconeogenesis](/source/Gluconeogenesis), especially in children, and may cause [lactic acidosis](/source/Lactic_acidosis), [ketoacidosis](/source/Ketoacidosis), and [acute kidney injury](/source/Acute_kidney_injury). Metabolic acidosis is compounded by respiratory failure. Patients may also present with hypothermia.

## Pathophysiology

Stage three of the five stages of inebriation, c. 1863–1868, by [Charles Percy Pickering](https://en.wikipedia.org/w/index.php?title=Charles_Percy_Pickering&action=edit&redlink=1)

Main article: [Pharmacology of ethanol](/source/Pharmacology_of_ethanol)

Alcohol is [metabolized](/source/Metabolized) by a normal [liver](/source/Liver) at the rate of about 8 grams of pure [ethanol](/source/Ethanol) per hour. 8 grams or 10 mL (0.34 US fl oz) is one British [standard unit](/source/Unit_of_alcohol). An "abnormal" liver with conditions such as [hepatitis](/source/Hepatitis), [cirrhosis](/source/Cirrhosis), [gall bladder](/source/Gall_bladder) disease, and [cancer](/source/Liver_cancer) is likely to result in a slower rate of metabolism.[24]

## Diagnosis

See also: [Blood alcohol content](/source/Blood_alcohol_content)

Alcohol intoxication is described as a [mental](/source/Mental_disorder) and [behavioural](/source/Abnormal_behaviour) [disorder](/source/Disorder_(medicine)) in the [International Classification of Diseases](/source/International_Classification_of_Diseases).[25] Definitive [diagnosis](/source/Medical_diagnosis) relies on a blood test for alcohol, usually performed as part of a [toxicology](/source/Toxicology) screen. [Law enforcement officers](/source/Law_enforcement_officer) in the United States and other countries often use [breathalyzer](/source/Breathalyzer) units and [field sobriety tests](/source/Field_sobriety_test) as more convenient and rapid alternatives to blood tests.[26] There are also various models of breathalyzer units that are available for consumer use. Because these may have varying reliability and may produce different results than the tests used for law-enforcement purposes, the results from such devices should be conservatively interpreted.

Many informal intoxication tests exist, which, in general, are unreliable and not recommended as deterrents to excessive intoxication or as indicators of the safety of activities such as motor vehicle driving, heavy equipment operation, machine tool use, etc.

For determining whether someone is intoxicated by alcohol by some means other than a blood-alcohol test, it is necessary to rule out other conditions such as [hypoglycemia](/source/Hypoglycemia), stroke, usage of other intoxicants, mental health issues, and so on. It is best if their behavior has been observed while the subject is sober to establish a baseline. Several well-known criteria can be used to establish a probable diagnosis. For a physician in the acute-treatment setting, acute alcohol intoxication can mimic other acute neurological disorders or is frequently combined with other [recreational drugs](/source/Recreational_drug) that complicate diagnosis and treatment.

## Management

Acute alcohol poisoning (an [overdose](/source/Overdose) of the drug) is a [medical emergency](/source/Medical_emergency) due to the risk of death from [respiratory depression](/source/Respiratory_depression) or [aspiration of vomit](/source/Aspiration_pneumonia) if vomiting occurs while the person is unresponsive. Emergency treatment strives to stabilize and maintain an open airway and sufficient breathing while waiting for the alcohol to metabolize. This can be done by removal of any vomit or, if the person is unconscious or has impaired [gag reflex](/source/Pharyngeal_reflex), intubation of the trachea.[27]

Other measures may include

- Administer the vitamin [thiamine](/source/Thiamine) to prevent [Wernicke–Korsakoff syndrome](/source/Wernicke%E2%80%93Korsakoff_syndrome), which can cause a [seizure](/source/Seizure) (more usually a treatment for chronic alcoholism, but in the acute context usually co-administered to ensure maximal benefit).

- [Hemodialysis](/source/Hemodialysis) if the blood concentration is very high at >130 mmol/L (>600 mg/dL)[28]

- Provide oxygen therapy as needed via nasal cannula or non-rebreather mask.

- Administration of intravenous fluids in cases involving [hypoglycemia](/source/Hypoglycemia) and [electrolyte imbalance](/source/Electrolyte_imbalance).[29]

- While the medication [metadoxine](/source/Metadoxine) may speed the breakdown of alcohol, use in alcohol intoxication requires further study as of 2017.[6][30] It is approved in a number of countries in Europe, as well as India and Brazil.[30]

Additional medication may be indicated for treatment of [nausea](/source/Nausea), [tremor](/source/Tremor), and [anxiety](/source/Anxiety).

## Clinical findings

### Hospital admissions

Alcohol intoxication was found to be prevalent in clinical populations within the United States involving people treated for[31] trauma[32] and in the age group of people aged within their 18th–24th years (in a study of a group for the years 1999–2004).[33] In the United States during the years 2010–2012, acute intoxication was found to be the direct cause of an average of 2,221 deaths, in the sample group of those aged within their 15th year or older.[8] The same mortality route is thought to cause indirectly more than 30,000 deaths per year.[5]

### Prognosis

Acute confusional state caused by [alcohol withdrawal](/source/Alcohol_withdrawal_syndrome), otherwise known as *[delirium tremens](/source/Delirium_tremens)*

A normal liver detoxifies the blood of alcohol over a period of time that depends on the initial level and the patient's overall physical condition. An abnormal liver will take longer but still succeeds, provided the alcohol does not cause [liver failure](/source/Liver_failure).[34]

People who have drunk heavily for several days or weeks may have [withdrawal](/source/Alcohol_withdrawal_syndrome) symptoms after the acute intoxication has subsided.[35]

A person consuming a dangerous amount of alcohol persistently can develop memory blackouts and idiosyncratic intoxication or pathological drunkenness symptoms.[36] [Long-term persistent consumption of excessive amounts of alcohol](/source/Long-term_effects_of_alcohol) can cause liver damage and have other deleterious health effects.

## Society and culture

See also: [List of deaths through alcohol](/source/List_of_deaths_through_alcohol)

A 1936 anti-drinking poster by [Aart van Dobbenburgh](/source/Aart_van_Dobbenburgh)

Alcohol intoxication is a [risk factor](/source/Risk_factor_(epidemiology)) in some cases of [catastrophic injury](/source/Catastrophic_injury), in particular for unsupervised [recreational](/source/Recreation) activity. A study in the [province](/source/Provinces_and_territories_of_Canada) of [Ontario](/source/Ontario) based on [epidemiological](/source/Epidemiology) data from 1986, 1989, 1992, and 1995 states that 79.2% of the 2,154 catastrophic injuries recorded for the study were preventable, of which 346 (17%) involved alcohol consumption.[37] The activities most commonly associated with alcohol-related catastrophic injury were [snowmobiling](/source/Snowmobiling) (124), fishing (41), [diving](/source/Underwater_diving) (40), [boating](/source/Boating) (31) and [canoeing](/source/Canoeing) (7), swimming (31), riding an [all-terrain vehicle](/source/All-terrain_vehicle) (24), and cycling (23).[37] These events are often associated with unsupervised young males, often inexperienced in the activity, and may result in [drowning](/source/Drowning).[37] [Alcohol and sex](/source/Alcohol_and_sex) are associated with [unsafe sex](/source/Safe_sex) and [drug-facilitated sexual assaults](/source/Drug-facilitated_sexual_assault). The ability for [sexual consent due to alcohol consumption](/source/Drugs_and_sexual_consent#Alcohol) might be difficult to determine and might require an [expert witness](/source/Expert_witness).[38]

### Legal issues

A drunk-driving simulator in [Montreal](/source/Montreal)

Laws on drunkenness vary. In the United States, it is a criminal offense for a person to be [drunk while driving a motorized vehicle](/source/Driving_under_the_influence), except in [Wisconsin](/source/Alcohol_laws_of_Wisconsin), where it is only a [fine](/source/Civil_infraction) for the first offense.[39] It is also a criminal offense to fly an aircraft or (in some [American states](/source/U.S._state)) to assemble or operate an [amusement park](/source/Amusement_park) ride while drunk.[40] Similar laws also exist in most other countries.

In some jurisdictions, it is also an offense to serve alcohol to an already-intoxicated person,[41] and, often, alcohol can only be sold by persons qualified to serve responsibly through [alcohol server training](/source/Alcohol_server_training).

The [blood alcohol content](/source/Blood_alcohol_content#Limits_by_country_(BAC:_Blood_Alcohol_Content)) (BAC) for legal operation of a vehicle is typically measured as a percentage of a unit volume of blood. This percentage ranges from 0.00% in Romania and the United Arab Emirates; to 0.05% in Australia, South Africa, Germany, Scotland, and New Zealand (0.00% for underage individuals); to 0.08% in [England and Wales](/source/England_and_Wales), the United States and Canada.[42]

The United States [Federal Aviation Administration](/source/Federal_Aviation_Administration) prohibits [crew members](/source/Aircrew) from performing their duties within eight hours of consuming an alcoholic beverage, while under the influence of alcohol, or with a BAC greater than 0.04%.[43][44]

In the United States, the United Kingdom, and Australia, [public intoxication](/source/Public_intoxication) is a crime (also known as "being drunk and disorderly" or "being drunk and incapable").[45]

In some countries, there are special facilities, sometimes known as "[drunk tanks](/source/Drunk_tanks)", for the temporary detention of persons found to be drunk.

### Religious views

Some religious groups permit the consumption of alcohol; some permit consumption but prohibit intoxication; others prohibit any amount of alcohol consumption altogether.

#### Christianity

*[Drunkenness of Noah](/source/Drunkenness_of_Noah)* by [Giovanni Bellini](/source/Giovanni_Bellini)

*[Lot and his daughters](/source/Lot_and_his_daughters)* by [Hendrick Goltzius](/source/Hendrick_Goltzius)

Some [denominations](/source/Christian_denomination) of Christianity, such as [Catholicism](/source/Catholic_Church), [Orthodoxy](/source/Orthodoxy) and [Lutheranism](/source/Lutheranism), use wine as a part of the [Eucharist](/source/Eucharist) (Holy Communion) and permit its consumption, but consider it sinful to become intoxicated.[46]

[Romans 13:13–14](/source/Romans_13#The_day_is_at_hand_(verses_11–14)),[47] [1 Corinthians 6](/source/1_Corinthians_6):9–11, [Galatians 5](/source/Galatians_5):19–21[48] and [Ephesians 5:18](/source/Ephesians_5#Verse_18)[49] are among a number of other Bible passages that speak against intoxication.

Some [Protestant Christian](/source/Protestantism) denominations prohibit the consumption of alcohol[50] based upon biblical passages that condemn drunkenness,[51] but others allow a [moderate](/source/Moderationism) rate of consumption.[52]

In the [Church of Jesus Christ of Latter-day Saints](/source/The_Church_of_Jesus_Christ_of_Latter-day_Saints), consumption is forbidden,[53] and [teetotalism](/source/Teetotalism) has become a distinguishing feature of its members. [Jehovah's Witnesses](/source/Jehovah's_Witnesses) allow moderate alcohol consumption among its members.

#### Islam

In the [Quran](/source/Quran),[54][55][56] there is a prohibition on the consumption of grape-based alcoholic beverages, and intoxication is considered an abomination in the [hadith](/source/Hadith) of [Muhammad](/source/Muhammad). The [schools of thought](/source/Madhhab) of [Islamic jurisprudence](/source/Fiqh) have interpreted this as a strict prohibition of the consumption of all types of alcohol and declared it to be *[haram](/source/Haram)* (lit. 'forbidden [in [Islam](/source/Islam)]'), although other uses may be permitted.[57]

#### Buddhism

Drunken [Immortal](/source/Xian_(Taoism)) supported and escorted by a demon, by Guo Xu, [Ming dynasty](/source/Ming_dynasty) China.

In [Buddhism](/source/Buddhism), in general, the consumption of intoxicants is discouraged for both monastics and lay followers. Many Buddhists observe a basic code of ethics known as the [five precepts](/source/Five_precepts), of which the fifth precept is an undertaking to refrain from the consumption of intoxicating substances[58] (except [for medical reasons](/source/Alcohols_(medicine))).[59] In the [*bodhisattva* vows](/source/Bodhisattva_vow) of the *[Brahmajala Sutra](/source/Brahmaj%C4%81la_S%C5%ABtra)*, observed by [Mahayana Buddhist](/source/Mahayana) communities, distribution of intoxicants is likewise discouraged, as well as consumption.[60]

#### Hinduism

In the [Gaudiya Vaishnavism](/source/Gaudiya_Vaishnavism) branch of [Hinduism](/source/Hinduism), one of the four regulative principles forbids the taking of intoxicants, including alcohol.

#### Judaism

Drunken [Lot](/source/Lot_(biblical_person)) and his daughters, from an illustrated Torah

In the Bible, the [Book of Proverbs](/source/Book_of_Proverbs) contains several chapters related to the negative effects of drunkenness and warns to stay away from [intoxicating beverages](/source/Alcoholic_drink). The [Book of Genesis](/source/Book_of_Genesis) refers to the use of wine by [Lot's daughters](/source/Lot's_daughters) to rape him. The story of [Samson](/source/Samson) in the [Book of Judges](/source/Book_of_Judges) tells of a monk from the [Israelite tribe of Dan](/source/Tribe_of_Dan) who, as a [Nazirite](/source/Nazirite), is prohibited from cutting his hair and drinking wine. [Proverbs 31:4](/source/Proverbs_31#The_words_of_Lemuel_(31:1–9)) warns against kings and other rulers drinking wine and similar alcoholic beverages, Proverbs 31:6–7 promotes giving such beverages to the perishing and wine to those whose lives are bitter as a coping mechanism against the likes of poverty and other troubles.[61]

In Judaism, in accordance with the biblical stance against drinking,[51] drinking wine is restricted for priests.[62] The biblical command to sanctify the [Sabbath](/source/Sabbath) and other holidays has been interpreted as having three ceremonial meals with wine or [grape juice](/source/Grape_juice), known as *[Kiddush](/source/Kiddush)*.[63][64] A number of [Jewish marriage ceremonies](/source/Jewish_views_on_marriage) end with the bride and groom drinking a shared cup of wine after reciting [seven blessings](/source/Sheva_Brachot); this occurs after a fasting day in some [Ashkenazi](/source/Ashkenazi_Jews) traditions. It has been customary and in many cases even mandated to drink moderately so as to stay [sober](/source/Sobriety), and only after the prayers are over.[65]

During the [Seder](/source/Passover_Seder) on [Passover](/source/Passover), there is an obligation to drink four ceremonial cups of wine while reciting the [Haggadah](/source/Haggadah). It has been assumed to be the source of the wine-drinking ritual at communion in some Christian groups.[66] During [Purim](/source/Purim), there is an obligation to become intoxicated; however, as with many other decrees, this has been avoided in many communities by allowing sleep during the day as a replacement.[67]

During the [U.S. Prohibition era](/source/Prohibition_in_the_United_States) in the 1920s, a [rabbi](/source/Rabbi) from the [Reform Judaism](/source/Reform_Judaism) movement proposed using grape juice for the ritual instead of wine. Although refuted at first, the practice became widely accepted by [orthodox Jews](/source/Orthodox_Judaism) as well.[68]

## Other animals

In the 1974 film *[Animals Are Beautiful People](/source/Animals_Are_Beautiful_People)*, an entire section was dedicated to showing many different animals, including monkeys, elephants, hogs, giraffes, and ostriches, eating over-ripe [marula](/source/Sclerocarya_birrea) tree fruit, causing them to sway and lose their footing in a manner similar to human drunkenness. Birds may become intoxicated with fermented berries, and some die colliding with hard objects when flying under the influence.[69][70]

In elephant warfare, practiced by the Greeks during the [Maccabean revolt](/source/Maccabean_revolt) and by [Hannibal](/source/Hannibal) during the [Punic Wars](/source/Punic_Wars), it has been recorded that the elephants would be given wine before the attack, and only then would they charge forward after being agitated by their driver.[71]

It is a regular practice to give small amounts of beer to race horses in Ireland. Ruminant farm animals have natural fermentation occurring in their stomach, and adding small quantities of alcoholic beverages to their water is generally harmless and will not cause them to become drunk.

Alcoholic beverages are extremely harmful to dogs,[72] and often for reasons of additives such as [xylitol](/source/Xylitol), an artificial sweetener in some mixers. Dogs can absorb ethyl alcohol in dangerous amounts through their skin as well as through drinking the liquid or consuming it in foods. Even fermenting bread dough can be dangerous to dogs.[73] In 1999, one of the royal footmen for Britain's Queen [Elizabeth II](/source/Elizabeth_II) was demoted from [Buckingham Palace](/source/Buckingham_Palace) due to his "party trick" of [spiking the meals and drinks](/source/Mickey_Finn_(drugs)) of the [Queen's pet corgi dogs](/source/Royal_corgis) with alcohol which in turn would lead the dogs to run around drunk.[74]

## See also

- [Beer portal](https://en.wikipedia.org/wiki/Portal:Beer)
- [Drink portal](https://en.wikipedia.org/wiki/Portal:Drink)
- [Medicine portal](https://en.wikipedia.org/wiki/Portal:Medicine)

- *[A Night of Serious Drinking](/source/A_Night_of_Serious_Drinking)*

- [Alcohol enema](/source/Alcohol_enema)

- [Alcohol flush reaction](/source/Alcohol_flush_reaction)

- [Disulfiram-alcohol reaction](/source/Disulfiram-alcohol_reaction)

- [Driving under the influence](/source/Driving_under_the_influence)

- *[In vino veritas](/source/In_vino_veritas)*

- [Long-term effects of alcohol consumption](/source/Long-term_effects_of_alcohol_consumption)

- [Low alcoholic drinks](/source/Non-alcoholic_drink#Low-alcoholic_drink)

- [Short-term effects of alcohol consumption](/source/Short-term_effects_of_alcohol_consumption)

## References

1. ^ [***a***](#cite_ref-Gar2007_1-0) [***b***](#cite_ref-Gar2007_1-1) Garfunkel, Lynn C.; Kaczorowski, Jeffrey; Christy, Cynthia (2007). [*Pediatric Clinical Advisor E-Book: Instant Diagnosis and Treatment*](https://books.google.com/books?id=pwajBQAAQBAJ&pg=PA13). Elsevier Health Sciences. p. 13. [ISBN](/source/ISBN_(identifier)) [978-0-323-07058-4](https://en.wikipedia.org/wiki/Special:BookSources/978-0-323-07058-4).

1. **[^](#cite_ref-Gup2016_2-0)** Gupta, P. K. (2016). [*Fundamentals of Toxicology: Essential Concepts and Applications*](https://books.google.com/books?id=u3mLCwAAQBAJ&pg=PA226). Academic Press. [ISBN](/source/ISBN_(identifier)) [978-0-12-805403-1](https://en.wikipedia.org/wiki/Special:BookSources/978-0-12-805403-1). Alcohol poisoning presents in two forms, acute and chronic. However, these are most often referred to as alcohol intoxication and alcohol addiction respectively.

1. ^ [***a***](#cite_ref-Mer2018_3-0) [***b***](#cite_ref-Mer2018_3-1) [***c***](#cite_ref-Mer2018_3-2) [***d***](#cite_ref-Mer2018_3-3) [***e***](#cite_ref-Mer2018_3-4) [***f***](#cite_ref-Mer2018_3-5) [***g***](#cite_ref-Mer2018_3-6) [***h***](#cite_ref-Mer2018_3-7) ["Alcohol Toxicity and Withdrawal"](https://www.merckmanuals.com/professional/special-subjects/recreational-drugs-and-intoxicants/alcohol-toxicity-and-withdrawal). *Merck Manuals Professional Edition*. Retrieved 24 May 2018.

1. ^ [***a***](#cite_ref-NHS2018_4-0) [***b***](#cite_ref-NHS2018_4-1) [***c***](#cite_ref-NHS2018_4-2) ["Alcohol poisoning"](https://www.nhs.uk/conditions/alcohol-poisoning/). *nhs.uk*. 17 October 2017. Retrieved 24 May 2018.

1. ^ [***a***](#cite_ref-DSM5_5-0) [***b***](#cite_ref-DSM5_5-1) [***c***](#cite_ref-DSM5_5-2) [***d***](#cite_ref-DSM5_5-3) [***e***](#cite_ref-DSM5_5-4) [***f***](#cite_ref-DSM5_5-5) [***g***](#cite_ref-DSM5_5-6) [***h***](#cite_ref-DSM5_5-7) [*Diagnostic and Statistical Manual of Mental Disorders (5th ed.)*](https://archive.org/details/diagnosticstatis0005unse/page/497), Arlington: American Psychiatric Publishing, 2013, pp. [497–499](https://archive.org/details/diagnosticstatis0005unse/page/497), [ISBN](/source/ISBN_(identifier)) [978-0-89042-555-8](https://en.wikipedia.org/wiki/Special:BookSources/978-0-89042-555-8)

1. ^ [***a***](#cite_ref-Jun2014_6-0) [***b***](#cite_ref-Jun2014_6-1) [***c***](#cite_ref-Jun2014_6-2) [***d***](#cite_ref-Jun2014_6-3) [***e***](#cite_ref-Jun2014_6-4) [***f***](#cite_ref-Jun2014_6-5) [***g***](#cite_ref-Jun2014_6-6) [***h***](#cite_ref-Jun2014_6-7) [***i***](#cite_ref-Jun2014_6-8) [***j***](#cite_ref-Jun2014_6-9) [***k***](#cite_ref-Jun2014_6-10) [***l***](#cite_ref-Jun2014_6-11) [***m***](#cite_ref-Jun2014_6-12) Jung, YC; Namkoong, K (2014). "Alcohol". *Alcohol and the Nervous System*. Handbook of Clinical Neurology. Vol. 125. pp. 115–21. [doi](/source/Doi_(identifier)):[10.1016/B978-0-444-62619-6.00007-0](https://doi.org/10.1016%2FB978-0-444-62619-6.00007-0). [ISBN](/source/ISBN_(identifier)) [978-0-444-62619-6](https://en.wikipedia.org/wiki/Special:BookSources/978-0-444-62619-6). [PMID](/source/PMID_(identifier)) [25307571](https://pubmed.ncbi.nlm.nih.gov/25307571).

1. **[^](#cite_ref-Mayo2019_7-0)** ["Alcohol use disorder – Symptoms and causes"](https://www.mayoclinic.org/diseases-conditions/alcohol-use-disorder/symptoms-causes/syc-20369243). *Mayo Clinic*. Retrieved 26 November 2019.

1. ^ [***a***](#cite_ref-Kan2015_8-0) [***b***](#cite_ref-Kan2015_8-1) Kanny, D; Brewer, RD; Mesnick, JB; Paulozzi, LJ; Naimi, TS; Lu, H (9 January 2015). ["Vital signs: alcohol poisoning deaths – United States, 2010–2012"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646044). *[Morbidity and Mortality Weekly Report](/source/Morbidity_and_Mortality_Weekly_Report)*. **63** (53): 1238–42. [PMC](/source/PMC_(identifier)) [4646044](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646044). [PMID](/source/PMID_(identifier)) [25577989](https://pubmed.ncbi.nlm.nih.gov/25577989).

1. **[^](#cite_ref-9)** ["Meaning of inebriation in English"](https://dictionary.cambridge.org/dictionary/english/inebriation). *dictionary.cambridge.org [Cambridge University Press](/source/Cambridge_University_Press)*. Retrieved 24 June 2021.{{[cite web](https://en.wikipedia.org/wiki/Template:Cite_web)}}: CS1 maint: deprecated archival service ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_deprecated_archival_service))

1. ^ [***a***](#cite_ref-:0_10-0) [***b***](#cite_ref-:0_10-1) ["Acute intoxication"](https://web.archive.org/web/20040704055527/http://www.who.int/substance_abuse/terminology/acute_intox/en/). World Health Organization. Archived from [the original](https://www.who.int/substance_abuse/terminology/acute_intox/en/) on 4 July 2004. Retrieved 24 May 2018.

1. **[^](#cite_ref-11)** Zakhari, Samir (2006). ["Overview: how is alcohol metabolized by the body?"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527027). *Alcohol Research & Health*. **29** (4): 245–254. [ISSN](/source/ISSN_(identifier)) [1535-7414](https://search.worldcat.org/issn/1535-7414). [PMC](/source/PMC_(identifier)) [6527027](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527027). [PMID](/source/PMID_(identifier)) [17718403](https://pubmed.ncbi.nlm.nih.gov/17718403).

1. ^ [***a***](#cite_ref-:1_12-0) [***b***](#cite_ref-:1_12-1) Sung, Hung-En (2016), "Alcohol and Crime", *Alcohol and Crime*, *The Blackwell Encyclopedia of Sociology*, Wiley, pp. 1–2, [doi](/source/Doi_(identifier)):[10.1002/9781405165518.wbeosa039.pub2](https://doi.org/10.1002%2F9781405165518.wbeosa039.pub2), [ISBN](/source/ISBN_(identifier)) [978-1-4051-6551-8](https://en.wikipedia.org/wiki/Special:BookSources/978-1-4051-6551-8){{[citation](https://en.wikipedia.org/wiki/Template:Citation)}}: CS1 maint: work parameter with ISBN ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_work_parameter_with_ISBN))

1. **[^](#cite_ref-13)** ["Ethanol Level: Reference Range, Interpretation, Collection and Panels"](https://emedicine.medscape.com/article/2090019-overview?pa=tZlaRqU6qrJZktQC5WWvdZUn3AyA7274pd4Hf2zSCvNL1t86c9tryKJmi8Xcaw5t8SIvl8zjYv73GUyW5rsbWA%3D%3D). *Medscape*. 22 April 2018. Retrieved 24 May 2018.

1. ^ [***a***](#cite_ref-:2_14-0) [***b***](#cite_ref-:2_14-1) Canfield, DV; Dubowski, KM; Cowan, M; Harding, PM (January 2014). "Alcohol Limits and Public Safety". *Forensic Science Review*. **26** (1): 9–22. [PMID](/source/PMID_(identifier)) [26226968](https://pubmed.ncbi.nlm.nih.gov/26226968).

1. ^ [***a***](#cite_ref-:3_15-0) [***b***](#cite_ref-:3_15-1) ["Alcohol Alert"](https://web.archive.org/web/20210228215303/https://pubs.niaaa.nih.gov/publications/AA72/AA72.htm). *pubs.niaaa.nih.gov*. Archived from [the original](https://pubs.niaaa.nih.gov/publications/AA72/AA72.htm) on 28 February 2021. Retrieved 24 June 2021.

1. ^ [***a***](#cite_ref-:4_16-0) [***b***](#cite_ref-:4_16-1) American Psychiatric Association (22 May 2013). [*Diagnostic and Statistical Manual of Mental Disorders*](https://psychiatryonline.org/doi/book/10.1176/appi.books.9780890425596) (5th ed.). American Psychiatric Association. [doi](/source/Doi_(identifier)):[10.1176/appi.books.9780890425596](https://doi.org/10.1176%2Fappi.books.9780890425596). [ISBN](/source/ISBN_(identifier)) [978-0-89042-555-8](https://en.wikipedia.org/wiki/Special:BookSources/978-0-89042-555-8).

1. ^ [***a***](#cite_ref-:5_17-0) [***b***](#cite_ref-:5_17-1) Belenko, Steven; Spohn, Cassia (2014). [*Drugs, Crime, and Justice*](https://books.google.com/books?id=w3pZDwAAQBAJ&pg=PT21). SAGE Publications. p. PT21. [ISBN](/source/ISBN_(identifier)) [978-1-4833-5542-9](https://en.wikipedia.org/wiki/Special:BookSources/978-1-4833-5542-9).

1. **[^](#cite_ref-18)** Martin, Scott C. (2014). [*The SAGE Encyclopedia of Alcohol: Social, Cultural, and Historical Perspectives*](https://books.google.com/books?id=R9i5BgAAQBAJ&pg=PT1382). SAGE Publications. p. PT1382. [ISBN](/source/ISBN_(identifier)) [978-1-4833-7438-3](https://en.wikipedia.org/wiki/Special:BookSources/978-1-4833-7438-3).

1. **[^](#cite_ref-19)** Kolig, Erich (2012). [*Conservative Islam: A Cultural Anthropology*](https://books.google.com/books?id=c3iEBiWQOBwC&pg=PA101). Lexington Books. p. 101. [ISBN](/source/ISBN_(identifier)) [978-0-7391-7425-8](https://en.wikipedia.org/wiki/Special:BookSources/978-0-7391-7425-8).

1. **[^](#cite_ref-20)** Latham, Katherine (11 December 2022). ["'Alcohol affects every organ': hangovers and how to survive them"](https://www.theguardian.com/society/2022/dec/11/alcohol-affects-every-organ-hangovers-and-how-to-survive-them). *The Guardian*. Retrieved 5 January 2023.

1. **[^](#cite_ref-21)** Dudley, Robert (May 2014). *The drunken monkey: why we drink and abuse alcohol*. Berkeley. [ISBN](/source/ISBN_(identifier)) [978-0-520-95817-3](https://en.wikipedia.org/wiki/Special:BookSources/978-0-520-95817-3). [OCLC](/source/OCLC_(identifier)) [869457130](https://search.worldcat.org/oclc/869457130).{{[cite book](https://en.wikipedia.org/wiki/Template:Cite_book)}}: CS1 maint: location missing publisher ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_location_missing_publisher))

1. **[^](#cite_ref-22)** ["Students > Alcohol Effects"](https://web.archive.org/web/20070505032342/http://www.alcohol.vt.edu/Students/alcoholEffects/index.htm). *Virginia Tech*. 5 May 2007. Archived from [the original](http://www.alcohol.vt.edu/Students/alcoholEffects/index.htm) on 5 May 2007.

1. **[^](#cite_ref-23)** The World Health Organization (2007) Alcohol and Injury in Emergency Departments

1. **[^](#cite_ref-24)** ["How long does alcohol stay in your blood?"](https://web.archive.org/web/20171231134001/https://www.nhs.uk/chq/pages/853.aspx). NHS Choices. 26 June 2018. Archived from [the original](https://www.nhs.uk/chq/Pages/853.aspx) on 31 December 2017. Retrieved 21 October 2017.

1. **[^](#cite_ref-25)** Drs; [Sartorius, Norman](/source/Norman_Sartorius); Henderson, A.S.; Strotzka, H.; Lipowski, Z.; Yu-cun, Shen; You-xin, Xu; Strömgren, E.; Glatzel, J.; Kühne, G.-E.; Misès, R.; Soldatos, C.R.; Pull, C.B.; Giel, R.; Jegede, R.; Malt, U.; Nadzharov, R.A.; Smulevitch, A.B.; Hagberg, B.; Perris, C.; Scharfetter, C.; Clare, A.; Cooper, J.E.; Corbett, J.A.; Griffith Edwards, J.; Gelder, M.; Goldberg, D.; Gossop, M.; Graham, P.; Kendell, R.E.; Marks, I.; Russell, G.; Rutter, M.; Shepherd, M.; West, D.J.; Wing, J.; Wing, L.; Neki, J.S.; Benson, F.; Cantwell, D.; Guze, S.; Helzer, J.; Holzman, P.; Kleinman, A.; Kupfer, D.J.; Mezzich, J.; Spitzer, R.; Lokar, J. ["The ICD-10 Classification of Mental and Behavioural Disorders Clinical descriptions and diagnostic guidelines"](https://www.who.int/classifications/icd/en/bluebook.pdf) (PDF). [World Health Organization](/source/World_Health_Organization). bluebook.doc. p. 65. [Archived](https://web.archive.org/web/20041017011412/http://www.who.int/classifications/icd/en/bluebook.pdf) (PDF) from the original on 17 October 2004. Retrieved 23 June 2021.

1. **[^](#cite_ref-26)** ["Random breath testing – Data by country"](http://apps.who.int/gho/data/view.main.54620). World Health Organization. Retrieved 25 June 2018.

1. **[^](#cite_ref-27)** Devi, G.; Castro, V. J.; Huitink, J.; Buitelaar, D.; Kosten, T.; O'Connor, P. (2003). "Management of Drug and Alcohol Withdrawal". *NEJM*. **349** (4): 405–407. [doi](/source/Doi_(identifier)):[10.1056/NEJM200307243490420](https://doi.org/10.1056%2FNEJM200307243490420). [PMID](/source/PMID_(identifier)) [12878752](https://pubmed.ncbi.nlm.nih.gov/12878752).

1. **[^](#cite_ref-28)** Adinoff, B.; Bone, G. H.; Linnoila, M. (May 1988). "Acute ethanol poisoning and the ethanol withdrawal syndrome". *Medical Toxicology*. **3** (3): 172–196. [doi](/source/Doi_(identifier)):[10.1007/BF03259881](https://doi.org/10.1007%2FBF03259881). [PMID](/source/PMID_(identifier)) [3041244](https://pubmed.ncbi.nlm.nih.gov/3041244). [S2CID](/source/S2CID_(identifier)) [35315540](https://api.semanticscholar.org/CorpusID:35315540).

1. **[^](#cite_ref-29)** Piccioni, A.; Tarli, C.; Cardone, S.; Brigida, M.; D'Addio, S.; Covino, M.; Zanza, C.; Merra, G.; Ojetti, V.; Gasbarrini, A.; Addolorato, G.; Franceschi, F. (24 September 2020). "Role of first aid in the management of acute alcohol intoxication: a narrative review". *European Review for Medical and Pharmacological Sciences*. **24** (17): 9121–9128. [doi](/source/Doi_(identifier)):[10.26355/eurrev_202009_22859](https://doi.org/10.26355%2Feurrev_202009_22859). [ISSN](/source/ISSN_(identifier)) [2284-0729](https://search.worldcat.org/issn/2284-0729). [PMID](/source/PMID_(identifier)) [32965003](https://pubmed.ncbi.nlm.nih.gov/32965003). [S2CID](/source/S2CID_(identifier)) [221862046](https://api.semanticscholar.org/CorpusID:221862046). In case of severe intoxication (blood alcohol concentration >1 g/L), it is necessary to prevent and to treat the potentially lethal metabolic effects of alcohol libation (in particular in adolescents) and to accelerate alcohol elimination from blood. It is necessary to support with intravenous fluids, treat hypoglycemia, hypotension, hypothermia and electrolyte imbalance, administer complex B and C vitamins, and support ventilation when necessary. To accelerate the elimination of ethanol from blood (assisting a faster recovery of the patient), two possible strategies can be applied: to perform a gastric lavage within two hours after drinking a considerable amount of alcohol or to administer metadoxine (pyridoxol L-2-pyrrolidone-5-carboxylate) that may be capable of decreasing ethanol blood levels by accelerating the urinary elimination of ethanol and acetaldehyde. Hypoglycemia is fasting-related and develops more frequently in young people (because of a lower reserve of liver glycogen); it is necessary to administer intravenous 5% glucose solution or, if possible, to invite the patient to eat fructose-rich foods and complex carbohydrates. Other metabolic effects could be electrolyte imbalance such as hypokalemia, hypomagnesaemia, hypocalcemia which must be appropriately and individually treated and replaced.

1. ^ [***a***](#cite_ref-Goh2017_30-0) [***b***](#cite_ref-Goh2017_30-1) Goh, ET; Morgan, MY (April 2017). ["Review article: pharmacotherapy for alcohol dependence – the why, the what and the wherefore"](http://discovery.ucl.ac.uk/1542523/3/Morgan_MYM%20accepted%20for%20deposit%20Pharmacotherapy%20for%20Alcohol%20Dependence%20Jan%202017%20for%20APT.pdf) (PDF). *Alimentary Pharmacology & Therapeutics*. **45** (7): 865–882. [doi](/source/Doi_(identifier)):[10.1111/apt.13965](https://doi.org/10.1111%2Fapt.13965). [PMID](/source/PMID_(identifier)) [28220511](https://pubmed.ncbi.nlm.nih.gov/28220511). [S2CID](/source/S2CID_(identifier)) [5431337](https://api.semanticscholar.org/CorpusID:5431337). [Archived](https://web.archive.org/web/20180719014723/http://discovery.ucl.ac.uk/1542523/3/Morgan_MYM%20accepted%20for%20deposit%20Pharmacotherapy%20for%20Alcohol%20Dependence%20Jan%202017%20for%20APT.pdf) (PDF) from the original on 19 July 2018.

1. **[^](#cite_ref-Von2008_31-0)** Vonghia, L; Leggio, L; Ferrulli, A; Bertini, M; Gasbarrini, G; Addolorato, G; Alcoholism Treatment Study, Group. (December 2008). "Acute alcohol intoxication". *European Journal of Internal Medicine*. **19** (8): 561–7. [doi](/source/Doi_(identifier)):[10.1016/j.ejim.2007.06.033](https://doi.org/10.1016%2Fj.ejim.2007.06.033). [PMID](/source/PMID_(identifier)) [19046719](https://pubmed.ncbi.nlm.nih.gov/19046719).

1. **[^](#cite_ref-32)** Almli, Lynn M.; Lori, Adriana; Meyers, Jacquelyn L.; Shin, Jaemin; Fani, Negar; Maihofer, Adam X.; Nievergelt, Caroline M.; Smith, Alicia K.; Mercer, Kristina B.; Kerley, Kimberly; Leveille, Jennifer M.; Feng, Hao; Abu-Amara, Duna; Flory, Janine D.; Yehuda, Rachel (September 2018). ["Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584945). *Addiction Biology*. **23** (5): 1145–1159. [doi](/source/Doi_(identifier)):[10.1111/adb.12569](https://doi.org/10.1111%2Fadb.12569). [ISSN](/source/ISSN_(identifier)) [1369-1600](https://search.worldcat.org/issn/1369-1600). [PMC](/source/PMC_(identifier)) [6584945](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584945). [PMID](/source/PMID_(identifier)) [29082582](https://pubmed.ncbi.nlm.nih.gov/29082582).

1. **[^](#cite_ref-33)** White, Aaron M.; Hingson, Ralph W.; Pan, I.-Jen; Yi, Hsiao-Ye (September 2011). ["Hospitalizations for alcohol and drug overdoses in young adults ages 18–24 in the United States, 1999–2008: results from the Nationwide Inpatient Sample"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357438). *Journal of Studies on Alcohol and Drugs*. **72** (5): 774–786. [doi](/source/Doi_(identifier)):[10.15288/jsad.2011.72.774](https://doi.org/10.15288%2Fjsad.2011.72.774). [ISSN](/source/ISSN_(identifier)) [1938-4114](https://search.worldcat.org/issn/1938-4114). [PMC](/source/PMC_(identifier)) [3357438](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357438). [PMID](/source/PMID_(identifier)) [21906505](https://pubmed.ncbi.nlm.nih.gov/21906505).

1. **[^](#cite_ref-34)** Morgan, TR (2003). ["Management of alcoholic hepatitis"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099359). *Drug and Therapeutics Bulletin*. **41** (2): 49–52. [doi](/source/Doi_(identifier)):[10.1136/dtb.2003.41749](https://doi.org/10.1136%2Fdtb.2003.41749). [PMC](/source/PMC_(identifier)) [3099359](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099359). [PMID](/source/PMID_(identifier)) [21960817](https://pubmed.ncbi.nlm.nih.gov/21960817).

1. **[^](#cite_ref-35)** DeBellis, R.; Smith, B. S.; Choi, S.; Malloy, M. (2005). "Management of Delirium Tremens". *J Intensive Care Med*. **20** (3): 164–173. [doi](/source/Doi_(identifier)):[10.1177/0885066605275353](https://doi.org/10.1177%2F0885066605275353). [PMID](/source/PMID_(identifier)) [15888905](https://pubmed.ncbi.nlm.nih.gov/15888905). [S2CID](/source/S2CID_(identifier)) [31848749](https://api.semanticscholar.org/CorpusID:31848749).

1. **[^](#cite_ref-36)** Gelder, M., Mayou, R. and Geddes, J. 2005. *Psychiatry*. 3rd ed. New York: Oxford. pp. 186.

1. ^ [***a***](#cite_ref-Tator_37-0) [***b***](#cite_ref-Tator_37-1) [***c***](#cite_ref-Tator_37-2) Tator, Charles H., ed. (2008). *Catastrophic Injuries in Sports and Recreation: Causes and Prevention: A Canadian Study* (2 ed.). [University of Toronto Press](/source/University_of_Toronto_Press). [ISBN](/source/ISBN_(identifier)) [978-0-8020-8967-0](https://en.wikipedia.org/wiki/Special:BookSources/978-0-8020-8967-0).

1. **[^](#cite_ref-q919_38-0)** Cornelius, Tara L.; Jozkowski, Kristen N.; Ross, Jody M.; Reidy, Dennis E.; Wehle, Shaun M.J.; Temple, Jeff R.; Drouin, Michelle (2024). ["Recent research involving consent, alcohol intoxication, and memory: Implications for expert testimony in sexual assault cases"](https://linkinghub.elsevier.com/retrieve/pii/S0160252724000839). *International Journal of Law and Psychiatry*. **97** 102034. [doi](/source/Doi_(identifier)):[10.1016/j.ijlp.2024.102034](https://doi.org/10.1016%2Fj.ijlp.2024.102034). Retrieved 24 April 2026.

1. **[^](#cite_ref-39)** ["Wisconsin Legislature: Chapter 346"](http://docs.legis.wisconsin.gov/statutes/statutes/346). *wisconsin.gov*.

1. **[^](#cite_ref-40)** ["Texas Penal Code § 49.065"](https://web.archive.org/web/20110926124717/http://law.onecle.com/texas/penal/49.065.00.html). Archived from [the original](http://law.onecle.com/texas/penal/49.065.00.html) on 26 September 2011.

1. **[^](#cite_ref-41)** ["Camden Council: Booze license suspended after selling alcohol to drunk customers"](https://web.archive.org/web/20090111052754/http://www.camden.gov.uk/ccm/content/press/2007/february/booze-license-suspended-after-selling-alcohol-to-drunk-customers.en). *camden.gov.uk*. Archived from [the original](http://www.camden.gov.uk/ccm/content/press/2007/february/booze-license-suspended-after-selling-alcohol-to-drunk-customers.en) on 11 January 2009. Retrieved 8 January 2009.

1. **[^](#cite_ref-42)** ["Drinking and Driving"](https://web.archive.org/web/20080702135901/http://www.icap.org/PolicyIssues/DrinkingandDriving/BACTable/tabid/199/Default.aspx). *icap.org*. Archived from [the original](http://www.icap.org/PolicyIssues/DrinkingandDriving/BACTable/tabid/199/Default.aspx) on 2 July 2008.

1. **[^](#cite_ref-43)** ["Federal Aviation Regulation Sec. 1.1 – General definitions"](http://www.risingup.com/fars/info/part1-1-FAR.shtml). *risingup.com*.

1. **[^](#cite_ref-44)** ["FAR Part 91 Sec. 91.17 effective as of 07/21/2006"](https://web.archive.org/web/20210227005600/https://rgl.faa.gov/Regulatory_and_Guidance_Library/rgFAR.nsf/0/28757d8ae4d7d671862571960066be86%21OpenDocument%26Click%3D). *faa.gov*. Archived from [the original](http://rgl.faa.gov/Regulatory_and_Guidance_Library/rgFAR.nsf/0/28757d8ae4d7d671862571960066be86%21OpenDocument%26Click%3D) on 27 February 2021. Retrieved 3 July 2008.

1. **[^](#cite_ref-45)** ["Licensing Act 1872"](http://www.statutelaw.gov.uk/content.aspx?activeTextDocId=1052305). *Acts of the United Kingdom Parliament*. Vol. 1872. 10 August 1872. Retrieved 8 May 2010.{{[cite news](https://en.wikipedia.org/wiki/Template:Cite_news)}}: CS1 maint: deprecated archival service ([link](https://en.wikipedia.org/wiki/Category:CS1_maint:_deprecated_archival_service))

1. **[^](#cite_ref-46)** [Bellarmine, Robert](/source/Robert_Bellarmine) (1902). ["Sermon 57: The Vice of Drunkenness."](https://en.wikisource.org/wiki/Sermons_from_the_Latins/Sermon_57). *Sermons from the Latins*. Benziger Brothers.

1. **[^](#cite_ref-47)** ["Bible Gateway passage: Romans 13:13-14 – New International Version"](https://www.biblegateway.com/passage/?search=Romans%2013%3A13-14&version=NIV). *Bible Gateway*.

1. **[^](#cite_ref-48)** ["Bible Gateway passage: Galatians 5:19-21 – New International Version"](https://www.biblegateway.com/passage/?search=Galatians%205%3A19-21&version=NIV). *Bible Gateway*.

1. **[^](#cite_ref-49)** ["Bible Gateway passage: Ephesians 5:18 – New International Version"](https://www.biblegateway.com/passage/?search=Ephesians%205%3A18&version=NIV). *Bible Gateway*.

1. **[^](#cite_ref-50)** ["On Alcohol Use in America"](https://web.archive.org/web/20131105012154/http://www.sbc.net/resolutions/amResolution.asp?ID=1156). *SBC Resolutions*. [Southern Baptist Convention](/source/Southern_Baptist_Convention). June 2006. Archived from [the original](http://www.sbc.net/resolutions/amResolution.asp?ID=1156) on 5 November 2013. Retrieved 7 June 2013.

1. ^ [***a***](#cite_ref-biblical_51-0) [***b***](#cite_ref-biblical_51-1) ["Matthew 1"](https://netbible.org/). *netbible.org*. Retrieved 31 December 2022.

1. **[^](#cite_ref-52)** ["Frequently Asked Questions: Alcohol"](http://www.lcms.org/Document.fdoc?src=lcm&id=576). *LCMS Views – Contemporary Issues*. [Lutheran Church–Missouri Synod](/source/Lutheran_Church%E2%80%93Missouri_Synod). p. 3. Retrieved 7 June 2013.

1. **[^](#cite_ref-53)** ["Doctrine and Covenants 89"](https://www.churchofjesuschrist.org/study/scriptures/dc-testament/dc/89?lang=eng). *churchofjesuschrist.org*.

1. **[^](#cite_ref-54)** ["Qur'an: 4:43"](https://web.archive.org/web/20101204153931/http://www.usc.edu/schools/college/crcc/engagement/resources/texts/muslim/quran/004.qmt.html#004.043). Usc.edu. Archived from [the original](http://www.usc.edu/schools/college/crcc/engagement/resources/texts/muslim/quran/004.qmt.html#004.043) on 4 December 2010. Retrieved 4 December 2010.

1. **[^](#cite_ref-55)** ["Qur'an: 2:19"](https://web.archive.org/web/20101204153812/http://www.usc.edu/schools/college/crcc/engagement/resources/texts/muslim/quran/002.qmt.html#002.219). Usc.edu. Archived from [the original](http://www.usc.edu/schools/college/crcc/engagement/resources/texts/muslim/quran/002.qmt.html#002.219) on 4 December 2010. Retrieved 4 December 2010.

1. **[^](#cite_ref-56)** ["Cmje"](https://web.archive.org/web/20101204173049/http://www.usc.edu/schools/college/crcc/engagement/resources/texts/muslim/quran/005.qmt.html#005.090). *usc.edu*. Archived from [the original](http://www.usc.edu/schools/college/crcc/engagement/resources/texts/muslim/quran/005.qmt.html#005.090) on 4 December 2010. Retrieved 4 December 2010.

1. **[^](#cite_ref-57)** Yilmaz, Ihsan (2004) [2005-01-31]. ["Post-Modern Muslim Legality and its Consequences"](https://books.google.com/books?id=4OrGYg31fi0C&q=Madhhab+alcohol&pg=PA158). *Muslim Laws, Politics And Society in Modern Nation States: Dynamic Legal Pluralisms in England, Turkey And Pakistan*. [Ashgate Publishing](/source/Ashgate_Publishing). p. 158. [ISBN](/source/ISBN_(identifier)) [978-0-7546-4389-0](https://en.wikipedia.org/wiki/Special:BookSources/978-0-7546-4389-0).

1. **[^](#cite_ref-58)** Gwynne, Paul (2017). ["The Buddhist Pancasila"](https://books.google.com/books?id=o08nDwAAQBAJ). *World Religions in Practice: A Comparative Introduction*. [John Wiley & Sons](/source/John_Wiley_%26_Sons). [ISBN](/source/ISBN_(identifier)) [978-1-118-97227-4](https://en.wikipedia.org/wiki/Special:BookSources/978-1-118-97227-4).

1. **[^](#cite_ref-59)** [Gombrich, Richard F.](/source/Richard_Gombrich) (1995). [*Buddhist Precept and Practice: Traditional Buddhism in the Rural Highlands of Ceylon*](https://books.google.com/books?id=V3Z-dHpBsBsC). [Kegan Paul, Trench and Company](/source/Kegan_Paul%2C_Trench_and_Company). p. 298. [ISBN](/source/ISBN_(identifier)) [978-0-7103-0444-5](https://en.wikipedia.org/wiki/Special:BookSources/978-0-7103-0444-5).

1. **[^](#cite_ref-60)** Benn, James A. (2005). ["Buddhism, Alcohol, and Tea in Medieval China"](https://books.google.com/books?id=XWPHAAAAQBAJ). In Sterckx, R. (ed.). *Of Tripod and Palate: Food, Politics, and Religion in Traditional China*. [Springer Nature](/source/Springer_Nature). p. 226. [ISBN](/source/ISBN_(identifier)) [978-1-4039-7927-8](https://en.wikipedia.org/wiki/Special:BookSources/978-1-4039-7927-8).

1. **[^](#cite_ref-61)** ["Proverbs 31: 4–7 NASB—It is not for kings, O Lemuel, It is"](http://www.biblegateway.com/passage/?search=Proverbs+31%3A+4-7&version=NASB). *Bible Gateway*.

1. **[^](#cite_ref-62)** The Talmudic decree set a schedule according to which the priests would take turns staying sober. The practice of becoming a 'biblical' monk, is discussed in a full tractate of the [Mishna](/source/Mishna) and Talmud. The Talmud tells of a family 'the sons of Reichab' who never drank wine, although it is not clear if this is considered good or bad.

1. **[^](#cite_ref-63)** ["תעלומת הקידוש השלישי | רותי פויכטונגר"](https://web.archive.org/web/20230206160541/https://musaf-shabbat.com/2016/08/21/%D7%AA%D7%A2%D7%9C%D7%95%D7%9E%D7%AA-%D7%94%D7%A7%D7%99%D7%93%D7%95%D7%A9-%D7%94%D7%A9%D7%9C%D7%99%D7%A9%D7%99-%D7%A8%D7%95%D7%AA%D7%99-%D7%A4%D7%95%D7%99%D7%9B%D7%98%D7%95%D7%A0%D7%92/). *מוסף "שבת" – לתורה, הגות ספרות ואמנות* (in Hebrew). 21 August 2016. Archived from [the original](https://musaf-shabbat.com/2016/08/21/%25d7%25aa%25d7%25a2%25d7%259c%25d7%2595%25d7%259e%25d7%25aa-%25d7%2594%25d7%25a7%25d7%2599%25d7%2593%25d7%2595%25d7%25a9-%25d7%2594%25d7%25a9%25d7%259c%25d7%2599%25d7%25a9%25d7%2599-%25d7%25a8%25d7%2595%25d7%25aa%25d7%2599-%25d7%25a4%25d7%2595%25d7%2599%25d7%259b%25d7%2598%25d7%2595%25d7%25a0%25d7%2592/) on 6 February 2023. Retrieved 31 December 2022.

1. **[^](#cite_ref-64)** The [Pharisees](/source/Pharisees), avoiding the [Zadokites](/source/Zadokites)' temple-based rituals, had installed many ceremonies which in a way change or contradict the literal meaning of the biblical protocol. These include the ceremony of lighting candles that stay lit during the Sabbath day, eating hot food from a fire lit previously, starting the Sabbath rituals on the night before, and drinking wine with the [Sabbath](/source/Sabbath) meal. See [Qimron Sabbath Laws](http://www.verednoam.com/articles/NoamQimronSabbathLaws.pdf) [Archived](https://web.archive.org/web/20210308005232/http://www.verednoam.com/articles/NoamQimronSabbathLaws.pdf) 8 March 2021 at the [Wayback Machine](/source/Wayback_Machine) Vered Noam, Department of Hebrew Culture Studies, [Tel Aviv University](/source/Tel_Aviv_University) ([Dead Sea Discoveries](http://www.brill.com/dead-sea-discoveries) [Archived](https://web.archive.org/web/20170131190805/http://www.brill.com/dead-sea-discoveries) 31 January 2017 at the [Wayback Machine](/source/Wayback_Machine), Brill Institute)

1. **[^](#cite_ref-65)** Posner, Menachem. ["What is Judaism's take on alcohol consumption?"](http://www.chabad.org/library/article_cdo/aid/581082/jewish/What-is-Judaisms-take-on-alcohol-consumption.htm). *Chabad.org*.

1. **[^](#cite_ref-66)** ["Was Jesus' Last Supper a Seder?"](https://www.biblicalarchaeology.org/daily/people-cultures-in-the-bible/jesus-historical-jesus/was-jesus-last-supper-a-seder/). *Biblical Archaeology Society*. 15 November 2022. Retrieved 31 December 2022.

1. **[^](#cite_ref-67)** The [Babylonian Talmud](/source/Babylonian_Talmud) says in Megillah 7b that "[Rava](/source/Rava_(amora)) said: A person is obligated to become intoxicated on [Purim](/source/Purim) until he is unaware of the difference between 'Cursed be [Haman](/source/Haman_(Bible))' and 'Blessed be [Mordechai](/source/Mordechai).'" This is taken to mean that on the Jewish festival of Purim, one is commanded to drink alcohol to the point of intoxication. See [Yanki Tauber](/source/Yanki_Tauber): [Are Jews actually supposed to get drunk on Purim?](http://www.chabad.org/global/popup/default_cdo/aid/2814/jewish/The-Purim-Drunk.htm) Chabad.org (referring to the Talmudic tractate Megillah (7b)).

1. **[^](#cite_ref-68)** ["Using grape juice for Kiddush"](https://web.archive.org/web/20210116114745/http://www.torahlab.org/doitright/using_grape_juice_for_kiddush/). *Torahlab website*. Archived from [the original](http://www.torahlab.org/doitright/using_grape_juice_for_kiddush/) on 16 January 2021.

1. **[^](#cite_ref-69)** Katz, Brigit (4 October 2018). ["Birds Are Acting Erratically in Minnesota. Blame It on the Alcohol"](https://www.smithsonianmag.com/smart-news/birds-are-acting-erratically-minnesota-blame-it-alcohol-180970468/). *[Smithsonian](/source/Smithsonian_(magazine))*. Retrieved 5 October 2018.

1. **[^](#cite_ref-70)** Kinde, Hailu; et al. (July 2012). "Strong circumstantial evidence for ethanol toxicosis in Cedar Waxwings (Bombycilla cedrorum)". *Journal of Ornithology*. **153** (3): 995–998. [Bibcode](/source/Bibcode_(identifier)):[2012JOrni.153..995K](https://ui.adsabs.harvard.edu/abs/2012JOrni.153..995K). [doi](/source/Doi_(identifier)):[10.1007/s10336-012-0858-7](https://doi.org/10.1007%2Fs10336-012-0858-7). [S2CID](/source/S2CID_(identifier)) [15546534](https://api.semanticscholar.org/CorpusID:15546534).

1. **[^](#cite_ref-71)** Lundin, Elizabeth (21 December 2021). ["Hannibal's Superweapon: The War Elephant"](https://historythings.com/hannibals-superweapon-the-war-elephant/). *History Things*. Retrieved 31 December 2022.

1. **[^](#cite_ref-72)** Klein, Dr Jerry (24 September 2019). ["How Harmful Is Alcohol To Dogs? What To Do if Your Dog Drinks Alcohol"](https://www.akc.org/expert-advice/vets-corner/is-alcohol-dangerous-for-dogs/). *akc.org*.

1. **[^](#cite_ref-73)** Means, Charlotte (28 February 2003). ["Bread dough toxicosis in dogs"](https://onlinelibrary.wiley.com/doi/10.1046/j.1435-6935.2003.00068.x). *Journal of Veterinary Emergency and Critical Care*. **13**: 39–41. [doi](/source/Doi_(identifier)):[10.1046/j.1435-6935.2003.00068.x](https://doi.org/10.1046%2Fj.1435-6935.2003.00068.x). Retrieved 19 April 2024.

1. **[^](#cite_ref-74)** ["News Lite"](https://web.archive.org/web/20150402161717/http://nl.newsbank.com/nl-search/we/Archives?p_product=LA&p_theme=la&p_action=search&p_maxdocs=200&p_topdoc=1&p_text_direct-0=0EF80EB2A69CA15E&p_field_direct-0=document_id&p_perpage=10&p_sort=YMD_date:D&s_trackval=GooglePM). *[Daily News of Los Angeles](/source/Daily_News_of_Los_Angeles)*. 23 July 1999. Archived from [the original](http://nl.newsbank.com/nl-search/we/Archives?p_product=LA&p_theme=la&p_action=search&p_maxdocs=200&p_topdoc=1&p_text_direct-0=0EF80EB2A69CA15E&p_field_direct-0=document_id&p_perpage=10&p_sort=YMD_date:D&s_trackval=GooglePM) on 2 April 2015. Retrieved 19 October 2022.

## Bibliography

- Bales, Robert F. "Attitudes toward Drinking in the Irish Culture". In: Pittman, David J. and Snyder, Charles R. (Eds.) *Society, Culture and Drinking Patterns*. New York: Wiley, 1962, pp. 157–187.

- Gentry, Kenneth L. Jr., *God Gave Wine: What the Bible Says about Alcohol*. Lincoln, Calif.: Oakdown, 2001.

- Rorabaugh, W.J. "The Alcoholic Republic," Chapter 2 & 5, [Oxford University Press](/source/Oxford_University_Press).

- Sigmund, Paul. *St. Thomas Aquinas on Politics and Ethics*. W.W. Norton & Company, Inc, 1988, p. 77.

- Walton, Stuart. *Out of It. A Cultural History of Intoxication*. [Penguin Books](/source/Penguin_Books), 2002. [ISBN](/source/ISBN_(identifier)) [0-14-027977-6](https://en.wikipedia.org/wiki/Special:BookSources/0-14-027977-6).

- Slingerland, Edward. *[Drunk: How We Sipped, Danced, and Stumbled Our Way to Civilization](/source/Drunk_(book))*. [Little, Brown Spark](/source/Little%2C_Brown_Spark), 2021.

## External links

[Wikisource](/source/Wikisource) has the text of the [1911 *Encyclopædia Britannica*](/source/Encyclop%C3%A6dia_Britannica_Eleventh_Edition) article "[Drunkenness](https://en.wikisource.org/wiki/1911_Encyclop%C3%A6dia_Britannica/Drunkenness)".

- [Alcohol overdose](https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/understanding-dangers-of-alcohol-overdose): [NIAAA](/source/NIAAA)

- [Alcohol poisoning](http://www.nhs.uk/conditions/alcohol-poisoning/Pages/Introduction.aspx) [Archived](https://web.archive.org/web/20171011032049/http://www.nhs.uk/Conditions/alcohol-poisoning/Pages/Introduction.aspx) 11 October 2017 at the [Wayback Machine](/source/Wayback_Machine): NHS Choices

Classification D ICD-11: 6C40, NE61 ICD-10: F10, T51 ICD-9-CM: 305.0, 980 MeSH: D000435 External resources MedlinePlus: 002644

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Adapted from the Wikipedia article [Alcohol intoxication](https://en.wikipedia.org/wiki/Alcohol_intoxication) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Alcohol_intoxication?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.