# APOL6

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**Apolipoprotein L6** is a [protein](/source/Protein) that in humans is encoded by the *APOL6* [gene](/source/Gene).[1][2][3]

This gene is a member of the [apolipoprotein](/source/Apolipoprotein) L [gene family](/source/Gene_family). The encoded protein is found in the [cytoplasm](/source/Cytoplasm), where it may affect the movement of [lipids](/source/Lipid) or allow the [binding](/source/Molecular_binding) of lipids to [organelles](/source/Organelle).[3]

## References

1. Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (May 2001). "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution". *Genomics*. **74** (1): 71–8. [doi:10.1006/geno.2001.6534](https://doi.org/10.1006/geno.2001.6534). [PMID 11374903](https://pubmed.ncbi.nlm.nih.gov/11374903)

1. Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA (Jan 2005). "Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells". *Mol Cancer Res*. **3** (1): 21–31. [doi:10.1158/1541-7786.21.3.1](https://doi.org/10.1158/1541-7786.21.3.1). [PMID 15671246](https://pubmed.ncbi.nlm.nih.gov/15671246). [S2CID 2545675](https://api.semanticscholar.org/CorpusID:2545675)

1. ["Entrez Gene: APOL6 apolipoprotein L, 6"](https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=80830)

## Further reading

- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". *Genome Res.*. **6** (9): 791–806. [doi:10.1101/gr.6.9.791](https://doi.org/10.1101/gr.6.9.791). [PMID 8889548](https://pubmed.ncbi.nlm.nih.gov/8889548)
- Dominguez O, Ashhab Y, Sabater L (1999). "Cloning of ARE-containing genes by AU-motif-directed display.". *Genomics*. **54** (2): 278–86. [doi:10.1006/geno.1998.5548](https://doi.org/10.1006/geno.1998.5548). [PMID 9828130](https://pubmed.ncbi.nlm.nih.gov/9828130)
- Dunham I, Shimizu N, Roe BA (1999). "The DNA sequence of human chromosome 22.". *Nature*. **402** (6761): 489–95. [Bibcode:1999Natur.402..489D](https://ui.adsabs.harvard.edu/abs/1999Natur.402..489D). [doi:10.1038/990031](https://doi.org/10.1038/990031). [PMID 10591208](https://pubmed.ncbi.nlm.nih.gov/10591208)
- Strausberg RL, Feingold EA, Grouse LH (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". *Proc. Natl. Acad. Sci. U.S.A.*. **99** (26): 16899–903. [Bibcode:2002PNAS...9916899M](https://ui.adsabs.harvard.edu/abs/2002PNAS...9916899M). [doi:10.1073/pnas.242603899](https://doi.org/10.1073/pnas.242603899). [PMC 139241](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241). [PMID 12477932](https://pubmed.ncbi.nlm.nih.gov/12477932)
- Clark HF, Gurney AL, Abaya E (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". *Genome Res.*. **13** (10): 2265–70. [doi:10.1101/gr.1293003](https://doi.org/10.1101/gr.1293003). [PMC 403697](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC403697). [PMID 12975309](https://pubmed.ncbi.nlm.nih.gov/12975309)
- Ota T, Suzuki Y, Nishikawa T (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". *Nat. Genet.*. **36** (1): 40–5. [doi:10.1038/ng1285](https://doi.org/10.1038/ng1285). [PMID 14702039](https://pubmed.ncbi.nlm.nih.gov/14702039)
- Collins JE, Wright CL, Edwards CA (2005). "A genome annotation-driven approach to cloning the human ORFeome". *Genome Biol.*. **5** (10): R84. [doi:10.1186/gb-2004-5-10-r84](https://doi.org/10.1186/gb-2004-5-10-r84). [PMC 545604](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545604). [PMID 15461802](https://pubmed.ncbi.nlm.nih.gov/15461802)
- Gerhard DS, Wagner L, Feingold EA (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". *Genome Res.*. **14** (10B): 2121–7. [doi:10.1101/gr.2596504](https://doi.org/10.1101/gr.2596504). [PMC 528928](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928). [PMID 15489334](https://pubmed.ncbi.nlm.nih.gov/15489334)

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Adapted from the Wikipedia article [APOL6](https://en.wikipedia.org/wiki/APOL6) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/APOL6?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.